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Title: Field trial of two dual vaccines against Mycoplasma agalactiae and Mycoplasma mycoides subsp. mycoides (large colony type) in goats
Authors: de la Fe, Christian
Assunção, Patricia
Saavedra, Pedro 
Tola, Sebastiana
Poveda Turrado, Carlos Guillermo 
Poveda Guerrero, José Bismarck 
UNESCO Clasification: 310905 Microbiología
310907 Patología
Keywords: Mycoplasma agalactiae
Mycoplasma mycoides
Issue Date: 2007
Publisher: 0264-410X
Journal: Vaccine 
Abstract: Two vaccines against Mycoplasma agalactiae and Mycoplasma mycoides subsp. mycoides (LC type) were developed using inactivated strains selected in previous characterization studies. The vaccines differed in terms of the adjuvants used: aluminium hydroxide (vaccine A) or aluminium hydroxide plus purified saponin (vaccine B). These vaccines were tested on 60 pregnant goats and 60 seronegative kids that were challenged by placing in a herd with a history of caprine contagious agalactia (CCA). Our findings indicate the effectiveness of the vaccines in preventing the appearance of new clinical signs such as mastitis, abortion, pneumonia and polyarthritis in CCA affected herds.
ISSN: 0264-410X
DOI: 10.1016/j.vaccine.2006.11.050
Source: Vaccine[ISSN 0264-410X],v. 25, p. 2340-2345
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