Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/42692
Title: Mesenteric venous thrombosis. Associated systemic disorders and hypercoagulability status of 21 surgical patients
Authors: Acosta-Merida, M. A.Asuncion 
Marchena-Gomez, J. 
Hemmersbach-Miller, M.
Conde-Martel, A. 
Hernandez-Romero, J. M.
UNESCO Clasification: 32 Ciencias médicas
Issue Date: 2007
Publisher: 0172-6390
Journal: Hepato-Gastroenterology 
Abstract: BACKGROUND/AIMS: Mesenteric venous thrombosis (MVT) is a rare condition with a challenging diagnosis. The aim of this study was to evaluate its association with systemic diseases and coagulation disorders. METHODOLOGY: Out of 132 patients operated on because of mesenteric ischemia between 1988 and 2002, all patients with a documented MVT were retrospectively recorded. Epidemiological and clinical data, complications and perioperative mortality were analyzed. RESULTS: Twenty-one patients, 10 male and 11 female, had MVT. Mean age was 63.8 years (SD: +/- 20.9). Arterial hypertension (57.1%) was the most prevalent associated condition. Other associated disorders were neoplasms (3 cases), liver cirrhosis (1 case), recurrent pulmonary thromboembolism (1 case), and one or more coagulation disorders (7 cases): lupus anticoagulant (2 cases); factor V Leiden (2 cases); protein S deficiency (3 cases); antithrombin III deficiency (1 case) and disseminated intravascular coagulation (1 case). Perioperative mortality was 33.3% (7 patients). Mean survival at the end of the study was 65.73 months (EE: 13.82). Patients with a coagulation disorder had a higher survival rate than those presenting without it (p = 0.02). CONCLUSIONS: MVT is still a lethal condition with a high morbidity that could be associated to systemic disorders and hypercoagulability syndromes in more than 50% of the cases.
URI: http://hdl.handle.net/10553/42692
ISSN: 0172-6390
Source: Hepato-Gastroenterology [ISSN 0172-6390], v. 54, p. 1080-1084
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