Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/42306
Campo DC Valoridioma
dc.contributor.authorLópez-Laguna, Nievesen_US
dc.contributor.authorMartínez-González, Miguel A.en_US
dc.contributor.authorToledo, Estefaniaen_US
dc.contributor.authorBabio, Nancyen_US
dc.contributor.authorSorlí, José, V.en_US
dc.contributor.authorRos, Emilioen_US
dc.contributor.authorMuñoz, Miguel Angelen_US
dc.contributor.authorEstruch, Ramonen_US
dc.contributor.authorLapetra, Joséen_US
dc.contributor.authorMuñoz-Bravo, Carlosen_US
dc.contributor.authorFiol, Miguelen_US
dc.contributor.authorSerra-Majem, Lluísen_US
dc.contributor.authorPinto, Xavieren_US
dc.contributor.authorGonzález, José, I.en_US
dc.contributor.authorFito, Montseen_US
dc.contributor.authorBasora, Josepen_US
dc.contributor.authorArós, Fernandoen_US
dc.contributor.authorRuiz-Canela, Miguelen_US
dc.date.accessioned2018-10-29T09:51:10Z-
dc.date.available2018-10-29T09:51:10Z-
dc.date.issued2018en_US
dc.identifier.issn0021-9150en_US
dc.identifier.urihttp://hdl.handle.net/10553/42306-
dc.description.abstractBackground and aims The PREDIMED (PREvención con DIeta MEDiterránea) is a multicentre trial analyzed as a prospective cohort study. A total of 7122 participants (aged 55–80 years) at high risk of cardiovascular disease in the PREDIMED trial were recruited in 11 centres in Spain. The prevalence of subjects with type 2 diabetes was 50%. Our objective was to determine the contribution of lifestyle factors to the development of peripheral artery disease (PAD). Methods Incident clinical PAD in relation to a healthy lifestyle 5-point score defined as adherence to a Mediterranean diet (MedDiet), moderate alcohol intake, regular physical activity, normal weight (BMI<25) and non-smoking was measured. Results Eighty-seven incident PAD cases were diagnosed during a median follow-up of 4.8 years. Compared with participants with 0 or 1 healthy lifestyle factor, the multivariable hazard ratio for PAD was 0.65 (95% confidence interval (CI) 0.37 to 1.14) for 2 factors, and 0.40 (0.22–0.72) for 3 or more. Moderate alcohol consumption, non-smoking, physical activity and following a MedDiet were significantly inversely associated with PAD whereas no association was found for normal weight (BMI<25 kg/m2). PAD risk monotonically decreased with an increasing number of lifestyle factors, and the greatest reduction was found for a score combining moderate alcohol consumption, MedDiet and physical activity or non-smoking. The multivariable-adjusted population attributable risk percent for the combination of these 4 factors was 80.5% (95% CI: 21.3%–95.1%). Conclusions Our results demonstrate that a simple healthy lifestyle score is associated with a substantially reduced risk of PAD in a high cardiovascular risk population with a high prevalence (50%) of subjects with type 2 diabetes.en_US
dc.languageengen_US
dc.publisher0021-9150
dc.relation.ispartofAtherosclerosisen_US
dc.sourceAtherosclerosis [ISSN 0021-9150], v. 275, p. 133-140en_US
dc.subject3206 Ciencias de la nutriciónen_US
dc.subject.otherPeripheral artery diseaseen_US
dc.subject.otherHealthy lifestyleen_US
dc.subject.otherMediterranean dieten_US
dc.subject.otherPhysical activityen_US
dc.subject.otherAlcohol consumptionen_US
dc.subject.otherSmokingen_US
dc.titleRisk of peripheral artery disease according to a healthy lifestyle score: The PREDIMED studyen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.atherosclerosis.2018.05.049en_US
dc.identifier.scopus85048242440-
dc.identifier.isi000442512600840-
dc.contributor.authorscopusid57202402068-
dc.contributor.authorscopusid7004290629-
dc.contributor.authorscopusid7003562288-
dc.contributor.authorscopusid24279242400-
dc.contributor.authorscopusid7004605575-
dc.contributor.authorscopusid57202569537-
dc.contributor.authorscopusid57207272093-
dc.contributor.authorscopusid7005989830-
dc.contributor.authorscopusid6507771144-
dc.contributor.authorscopusid35201757300-
dc.contributor.authorscopusid7005315313-
dc.contributor.authorscopusid57202560799-
dc.contributor.authorscopusid7004430064-
dc.contributor.authorscopusid57192590236-
dc.contributor.authorscopusid6602891390-
dc.contributor.authorscopusid23017786300-
dc.contributor.authorscopusid7004158382-
dc.contributor.authorscopusid6603417884-
dc.description.lastpage140en_US
dc.description.firstpage133en_US
dc.relation.volume275en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.contributor.daisngid27897358-
dc.contributor.daisngid17754-
dc.contributor.daisngid140645-
dc.contributor.daisngid691402-
dc.contributor.daisngid495748-
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dc.contributor.daisngid9921613-
dc.contributor.daisngid19357-
dc.contributor.daisngid34937322-
dc.contributor.daisngid4082099-
dc.contributor.daisngid78038-
dc.contributor.daisngid28836-
dc.contributor.daisngid115192-
dc.contributor.daisngid1865872-
dc.contributor.daisngid74443-
dc.contributor.daisngid348215-
dc.contributor.daisngid106289-
dc.contributor.daisngid31761100-
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Lopez-Laguna, N-
dc.contributor.wosstandardWOS:Martinez-Gonzalez, MA-
dc.contributor.wosstandardWOS:Toledo, E-
dc.contributor.wosstandardWOS:Babio, N-
dc.contributor.wosstandardWOS:Sorli, JV-
dc.contributor.wosstandardWOS:Ros, E-
dc.contributor.wosstandardWOS:Munoz, MA-
dc.contributor.wosstandardWOS:Estruch, R-
dc.contributor.wosstandardWOS:Lapetra, J-
dc.contributor.wosstandardWOS:Munoz-Bravo, C-
dc.contributor.wosstandardWOS:Fiol, M-
dc.contributor.wosstandardWOS:Serra-Majem, L-
dc.contributor.wosstandardWOS:Pinto, X-
dc.contributor.wosstandardWOS:Gonzalez, JI-
dc.contributor.wosstandardWOS:Fito, M-
dc.contributor.wosstandardWOS:Basora, J-
dc.contributor.wosstandardWOS:Aros, F-
dc.contributor.wosstandardWOS:Ruiz-Canela, M-
dc.date.coverdateAgosto 2018en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr1,748
dc.description.jcr4,255
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR IUIBS: Nutrición-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.orcid0000-0002-9658-9061-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameSerra Majem, Luis-
Colección:Artículos
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