Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/41716
Title: A healthy diet for your heart and your brain
Authors: Sanchez-Villegas, Almudena 
Martinez-Lapiscina, Elena H.
UNESCO Clasification: 3206 Ciencias de la nutrición
320105 Psicología clínica
Keywords: Mediterranean diet
Cognitive decline
Dementia
Alzheimer’s disease
Depression
Mental health
Inflammation
Endothelium
Issue Date: 2018
Journal: The Prevention Of Cardiovascular Disease Through The Mediterranean Diet
Abstract: Considering the increased rate of incidence and the lack of curative treatments on the horizon, dementia has become a priority for public health. Since the etiology of Alzheimer’s and vascular degenerative diseases are far to be completely understood, dementia may not be curable yet. On the other hand, unipolar depression affects more than 151 million people worldwide and it is projected to be the leading cause of disability-adjusted life years lost in 2030. Consequently, depressive disorders pose heavy health and economic burdens and thus their prevention is a global public health priority. Oxidative stress, inflammation, and vascular comorbidities play a key role in the progression of the pathogenic changes that are ultimately responsible for the appearance of dementia. Likewise, metabolic processes such as reduced insulin sensitivity or elevations in plasma homocysteine levels and, perhaps more importantly, increased production of proinflammatory cytokines and endothelial dysfunction, seem to be also the major factors responsible for the link between depression and cardio-metabolic disorders. The antioxidative and antiinflammatory properties of the Mediterranean Diet as well the benefit in vascular profile of this dietary pattern supports the approach of recommending this dietary pattern as a feasible nonpharmacological strategy to combat the increased rate of dementia worldwide. Some evidences have also pointed out its beneficial role against depression.
URI: http://hdl.handle.net/10553/41716
ISBN: 9780128112595
DOI: 10.1016/B978-0-12-811259-5.00011-1
Source: Prevention of cardiovascular disease through the mediterranean diet / Almudena Sánchez-Villegas y Ana Sánchez-Tainta (Eds). Elsevier. Academic Press. 240 p.
Appears in Collections:Capítulo de libro
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