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http://hdl.handle.net/10553/41709
Título: | Locus coeruleus complex of the family Delphinidae | Autores/as: | Sacchini, Simona Arbelo, Manuel Bombardi, Cristiano Fernandez, Antonio Cozzi, Bruno Bernaldo de Quiros, Yara Herráez, Pedro |
Clasificación UNESCO: | 240111 Patología animal | Palabras clave: | Human Substantia-Nigra Tyrosine-Hydroxylase Immunohistochemistry Catecholamine-Containing Neurons Dolphin Tursiops-Truncatus Alzheimers-Disease, et al. |
Fecha de publicación: | 2018 | Proyectos: | Bioindicadores Del Sindrome de Estres Post Varamiento en Cetaceos Patología Embolico "Gaseosa/Grasa" en Cetáceos Patologia Embolica (Gaseosa/Grasa) en Cetaceos (Pegcet-3) |
Publicación seriada: | Scientific Reports | Resumen: | The locus coeruleus (LC) is the largest catecholaminergic nucleus and extensively projects to widespread areas of the brain and spinal cord. The LC is the largest source of noradrenaline in the brain. To date, the only examined Delphinidae species for the LC has been a bottlenose dolphin (Tursiops truncatus). In our experimental series including different Delphinidae species, the LC was composed of five subdivisions: A6d, A6v, A7, A5, and A4. The examined animals had the A4 subdivision, which had not been previously described in the only Delphinidae in which this nucleus was investigated. Moreover, the neurons had a large amount of neuromelanin in the interior of their perikarya, making this nucleus highly similar to that of humans and non-human primates. This report also presents the first description of neuromelanin in the cetaceans' LC complex, as well as in the cetaceans' brain. | URI: | http://hdl.handle.net/10553/41709 | ISSN: | 2045-2322 | DOI: | 10.1038/s41598-018-23827-z | Fuente: | Scientific Reports [ISSN 2045-2322], v. 8 (5486) |
Colección: | Artículos |
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