Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/41628
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dc.contributor.authorVillar, Jesúsen_US
dc.contributor.authorCabrera-Benítez, Nuria E.en_US
dc.contributor.authorValladares, Franciscoen_US
dc.contributor.authorGarcía-Hernández, Soniaen_US
dc.contributor.authorRamos-Nuez, Ángelaen_US
dc.contributor.authorMartín Barrasa, José Luisen_US
dc.contributor.authorMuros, Mercedesen_US
dc.contributor.authorKacmarek, Robert M.en_US
dc.contributor.authorSlutsky, Arthur S.en_US
dc.date.accessioned2018-07-23T10:30:28Z-
dc.date.available2018-07-23T10:30:28Z-
dc.date.issued2015en_US
dc.identifier.issn1466-609Xen_US
dc.identifier.urihttp://hdl.handle.net/10553/41628-
dc.description.abstractMost patients with sepsis and acute lung injury require mechanical ventilation to improve oxygenation and facilitate organ repair. Mast cells are important in response to infection and resolution of tissue injury. Since tryptase secreted from mast cells has been associated with tissue fibrosis, we hypothesized that tryptase would be involved in the early development of ventilator-induced pulmonary fibrosis in a clinically relevant model of sepsis-induced lung injury.en_US
dc.languageengen_US
dc.relation.ispartofCritical Careen_US
dc.sourceCritical Care [ISSN 1466-609X], v. 19 (1), p. 138en_US
dc.subject3109 Ciencias veterinariasen_US
dc.subject320508 Enfermedades pulmonaresen_US
dc.subject.otherLung injuryen_US
dc.subject.otherAcute lung injuryen_US
dc.subject.otherAcute respiratory distress syndromeen_US
dc.subject.otherTryptaseen_US
dc.subject.otherAcute respiratory distress syndrome patienten_US
dc.titleTryptase is involved in the development of early ventilator-induced pulmonary fibrosis in sepsis-induced lung injuryen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticlees
dc.identifier.doi10.1186/s13054-015-0878-9en_US
dc.identifier.pmid25871971-
dc.identifier.scopus2-s2.0-84926666978-
dc.identifier.isi000352354600001-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/84926666978-
dc.identifier.eissn1466-609X-
dc.identifier.issue1-
dc.description.firstpage138-
dc.relation.volume19-
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.ulpgces
dc.description.jcr4,95
dc.description.jcrqQ1
dc.description.scieSCIE
item.fulltextCon texto completo-
item.grantfulltextopen-
crisitem.author.deptGIR IUSA-ONE HEALTH 2 - Sanidad Animal de la Acuicultura y Especies Silvestres, Enfermedades Infecciosas y Seguridad Alimentaria-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.orcid0000-0002-3280-9838-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.fullNameMartín Barrasa, José Luis-
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