Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/41618
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dc.contributor.authorCabrera-Benítez, Nuria E.en_US
dc.contributor.authorValladares, Franciscoen_US
dc.contributor.authorGarcía-Hernández, Soniaen_US
dc.contributor.authorRamos-Nuez, Ángelaen_US
dc.contributor.authorMartín Barrasa, José Luisen_US
dc.contributor.authorMartínez-Saavedra, María-Teresaen_US
dc.contributor.authorRodríguez-Gallego, Carlosen_US
dc.contributor.authorMuros, Mercedesen_US
dc.contributor.authorFlores, Carlosen_US
dc.contributor.authorLiu, Mingyaoen_US
dc.contributor.authorSlutsky, Arthur S.en_US
dc.contributor.authorVillar, Jesúsen_US
dc.date.accessioned2018-07-20T07:53:56Z-
dc.date.available2018-07-20T07:53:56Z-
dc.date.issued2015en_US
dc.identifier.issn1530-0293en_US
dc.identifier.urihttp://hdl.handle.net/10553/41618-
dc.description.abstractPulmonary endothelial cell injury is central to the pathophysiology of acute lung injury. Mechanical ventilation can cause endothelial disruption and injury, even in the absence of preexisting inflammation. Platelet-endothelial cell adhesion molecule-1 is a transmembrane protein connecting adjacent endothelial cells. We hypothesized that injurious mechanical ventilation will increase circulating lung endothelial-derived microparticles, defined as microparticles positive for platelet-endothelial cell adhesion molecule-1, which could serve as potential biomarkers and mediators of ventilator-induced lung injury.en_US
dc.languageengen_US
dc.relation.ispartofCritical Care Medicineen_US
dc.sourceCritical Care Medicine [ISSN 1530-0293], v. 43 (12), e551-559. Erratum in: Crit Care Med. 2016 Mar;44(3):e180en_US
dc.subject320508 Enfermedades pulmonaresen_US
dc.titleAltered profile of circulating endothelial-derived microparticles in ventilator-induced lung injuryen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticlees
dc.identifier.doi10.1097/CCM.0000000000001280en_US
dc.identifier.pmid26308427-
dc.identifier.scopus2-s2.0-84947210564-
dc.identifier.isi000365481800002-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/84947210564-
dc.identifier.eissn1530-0293-
dc.description.lastpagee559-
dc.identifier.issue12-
dc.description.firstpagee551-
dc.relation.volume43-
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.ulpgces
dc.description.sjr3,917
dc.description.jcr7,422
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR IUSA-ONE HEALTH 2 - Sanidad Animal de la Acuicultura y Especies Silvestres, Enfermedades Infecciosas y Seguridad Alimentaria-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.deptGIR IUIBS: Farmacología Molecular y Traslacional-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0002-3280-9838-
crisitem.author.orcid0000-0002-4344-8644-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameMartín Barrasa, José Luis-
crisitem.author.fullNameRodríguez Gallego, José Carlos-
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