Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/40354
Título: Early and intermediate age-related macular degeneration: update and clinical review
Autores/as: García-Layana, A.
Cabrera López, Francisco Antonio 
Garcia-Arumi, Jose
Arias-Barquet, Lluis
Ruiz-Moreno, Jose M.
Clasificación UNESCO: 320109 Oftalmología
Palabras clave: Age-related macular degeneration
Early AMD
Risk factors
Classification
Prevention, et al.
Fecha de publicación: 2017
Publicación seriada: Clinical interventions in aging 
Resumen: Age-related macular degeneration (AMD) is the leading cause of irreversible central vision loss in developed countries. With the aging of population, AMD will become globally an increasingly important and prevalent disease worldwide. It is a complex disease whose etiology is associated with both genetic and environmental risk factors. An extensive decline in the quality of life and progressive need of daily living assistance resulting from AMD among those most severely affected highlights the essential role of preventive strategies, particularly advising patients to quit smoking. In addition, maintaining a healthy diet, controlling other risk factors (such as hypertension, obesity, and atherosclerosis), and the use of nutritional supplements (antioxidants) are recommendable. Genetic testing may be especially important in patients with a family history of AMD. Recently, unifying criteria for the clinical classification of AMD, defining no apparent aging changes; normal aging changes; and early, intermediate, and late AMD stages, are of value in predicting AMD risk of progression and in establishing recommendations for the diagnosis, therapeutic approach, and follow-up of patients. The present review is focused on early and intermediate AMD and presents a description of the clinical characteristics and ophthalmological findings for these stages, together with algorithms for the diagnosis and management of patients, which are easily applicable in daily clinical practice.
URI: http://hdl.handle.net/10553/40354
ISSN: 1178-1998
DOI: 10.2147/CIA.S142685
Fuente: Clinical Interventions in Aging [ISSN 1178-1998], v. 12, p. 1579-1587
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