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Title: Transfer entropy to characterize brain-heart topology in sleep apnea patients treated with continuous positive airway pressure
Authors: Cerquera, A.
Orjuela-Cañón, A.
Roa-Huertas, J.
Freund, J.A.
Juliá Serdá, José Gabriel
Ravelo-García, Antonio 
UNESCO Clasification: 3314 Tecnología médica
Keywords: Brain-heart network
Continuous positive airway pressure (CPAP)
Obstructive sleep apnea (OSA)
Transfer entropy
Issue Date: 2017
Journal: Proceedings of SPIE - The International Society for Optical Engineering 
Conference: 12th International Symposium on Medical Information Processing and Analysis (SIPAIM) 
12th International Symposium on Medical Information Processing and Analysis, SIPAIM 2016 
Abstract: Transfer entropy (TE) is a nonlinear metric employed recently in polysomnography (PSG) recordings to quantify the topological characteristics of the brain-heart physiological network. The present study applies the TE to eva-luate its usefulness to identify quantitative differences in PSG registers of patients diagnosed with oclusive sleep apnea (OSA), before and after a continuous positive air pressure (CPAP) therapy. PSG recordings corresponding to 19 OSA patients were analysed under the rationale that the set of EEG subbands represents the sympathetic activity of the autonomic nervous system (ANS), and the high frequency component of the heart rate variability (HRV) represents the parasympathetic activity. The TE was computed based on a binning estimation and the results were analyzed via effect size calculation. The results showed that the sympathetic activity is increased in the presence of OSA, which is represented by the increased flow of information among brain subsystems and dropping to values close to zero during CPAP therapy. In contrast, the parasympathetic activity showed to be reduced in the presence of OSA and augmented during the CPAP therapy.
ISBN: 9781510607781
ISSN: 0277-786X
DOI: 10.1117/12.2256836
Source: Proceedings of SPIE - The International Society for Optical Engineering[ISSN 0277-786X],v. 10160 (1016003)
Appears in Collections:Actas de congresos
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