Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/35736
Title: Identification of some main Streptococcus iniae associated proteins: relationship
Authors: El Aamri, Fatima
Guillén, José Ángel 
Padilla, Daniel 
Acosta, Félix 
Real Valcárcel, Fernando 
UNESCO Clasification: 3109 Ciencias veterinarias
Keywords: Bacteria
Proteins
Genome
Shaving
Streptococcus iniae
Surfacome
Issue Date: 2017
Journal: Veterinary Research Communications 
Abstract: The surface-associated proteins play a key role in bacterial physiology and pathogenesis, and are the major targets in the development of new vaccines. These proteins contribute to the adaptation of bacteria to different hosts and environments. To study differences at the genomic level, we first sequenced the whole genome of Streptococcus iniae from fish (IUSA-1 strain) and compared it to Streptococcus iniae from human (9117 strain), revealing a high similitude between both strains. To gain further insights into host- and environment-specific differences, we then studied proteins in silico and by High Performance Liquid Chromatography. This approach successfully identified 54 secreted and surface proteins, including several proteins involved in cell wall synthesis and transport of solutes, as well as proteins with yet unknown function. These proteins highlight as interesting targets for further investigation in the interaction between Streptococcus iniae and its environment. Results reported in this study have shown a first analysis about the predicted and experimental associated proteins of Streptococcus iniae isolated from two different hosts: human and fish.
URI: http://hdl.handle.net/10553/35736
ISSN: 0165-7380
DOI: 10.1007/s11259-017-9675-z
Source: Veterinary Research Communications[ISSN 0165-7380],v. 41, p. 85-95
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