Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/35427
|Title:||Benign bilateral Adenomyoepithelioma of the mammary gland in a ring-tailed lemur (Lemur catta)||Authors:||Suárez-Bonnet, A.
Rodríguez Grau-Bassas, J. Enrique
Herráez Thomas, Pedro
Priestnall, S. L.
Espinosa de los Monteros, A.
|UNESCO Clasification:||3109 Ciencias veterinarias
240111 Patología animal
|Issue Date:||2017||Journal:||Journal of Comparative Pathology||Abstract:||Naturally occurring mammary tumours are uncommon in prosimians. A 20-year-old female ring-tailed lemur (Lemur catta) developed bilateral enlargement of the mammary glands. Surgical removal revealed that both masses were comprised of multiple nodules and cystic areas that entirely replaced the normal glands. Histologically, a benign neoplastic biphasic cellular proliferation, composed of luminal epithelial and basal myoepithelial components, was identified. Immunohistochemical analysis for expression of cytokeratin (CK) AE1 /AE3, CK7, CK5 + 8, CK14, vimentin, p63 and 14-3-3 sigma highlighted the biphasic nature of the neoplasm. A low mitotic count, low Ki67 labelling index, expression of oestrogen receptor-alpha, lack of expression of human epidermal growth factor receptor and a 3-year disease-free period without recurrence supported the benign nature of the tumour. Macroscopically, histologically and immunohistochemically this neoplasm resembled benign adenomyoepithelioma of the breast in women. This is the first complete report of a naturally occurring mammary tumour in a ring-tailed lemur.||URI:||http://hdl.handle.net/10553/35427||ISSN:||0021-9975||DOI:||10.1016/j.jcpa.2017.06.009||Source:||Journal of Comparative Pathology [ISSN 0021-9975], v. 157 (2-3), p. 85-89|
|Appears in Collections:||Artículos|
checked on Apr 4, 2020
Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.