Please use this identifier to cite or link to this item: https://accedacris.ulpgc.es/handle/10553/143224
Title: Effectiveness of combined arthrocentesis with platelet-rich plasma, platelet rich-fibrin, hyaluronic acid, corticosteroids and non-steroidal anti-inflammatory drugs in temporomandibular joint osteoarthritis: a systematic review and meta-analysis of randomized clinical trials
Authors: Betancor Pérez, Marilia 
Loro Ferrer, Juan Francisco 
Martín Hernán, Fátima
Velázquez Cayón, Rocío Trinidad
UNESCO Clasification: 32 Ciencias médicas
3201 Ciencias clínicas
3213 Cirugía
3209 Farmacología
Issue Date: 2025
Journal: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 
Abstract: Objective: To stablish whether combined arthrocentesis with platelet-rich plasma, fibrin-rich plasma, hyaluronic acid, corticosteroids and non-steroidal anti-inflammatory drugs is more effective than exclusive arthrocentesis in patients with temporomandibular joint osteoarthritis. Study Design: A bibliographic search was conducted in Pubmed, Web of Science, Embase and Scopus in July 2024. RCTs were included. The PRISMA checklist was followed. The study is registered with PROSPERO, number CRD42024542631. Results: Six RCTs were included with a total of 179 patients. For the variable of maximum oral opening, a better response was observed in the combined arthrocentesis group than in the arthrocentesis group at 6 months (P = .011) and at 12 months (P < .001). For the pain variable, there were no significant differences between the groups at 6 months (P = .300) while at 12 months a better response was observed for the experimental group (P < .001). Conclusion: Combined arthrocentesis techniques show significant improvements in maximum mouth opening at six and twelve months and in pain at twelve months pos-treatment. However, the lack of protocol development and the scarcity of similar studies highlight the heterogeneity of the results.
URI: https://accedacris.ulpgc.es/handle/10553/143224
ISSN: 2212-4403
DOI: 10.1016/j.oooo.2025.06.003
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology [ISSN 2212-4403], (2025)
Appears in Collections:Artículos
Adobe PDF (1,03 MB)
Show full item record

Google ScholarTM

Check

Altmetric


Share



Export metadata



Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.