Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/133236
Title: Caprine Paratuberculosis Seroprevalence and Immune Response to Anti-Mycobacterium avium Subspecies paratuberculosis Vaccination on the Canary Islands, Spain
Authors: Stefanova, Elena Plamenova 
Paz Sanchez,Yania 
Quesada Canales, Ildefonso Óscar 
Quintana Montesdeoca, María Del Pino 
Espinosa De Los Monteros Y Zayas, Antonio 
Ramírez Corbera, Ana Sofía 
Fernández Rodríguez, Antonio Jesús 
Andrada Borzollino, Marisa Ana 
UNESCO Clasification: 310905 Microbiología
241404 Bacteriología
310407 Ovinos
230227 Proteínas
Keywords: ELISA
Johne’s disease
goat
antibody
serological test, et al
Issue Date: 2024
Project: La Paratuberculosis (PTB) Caprina, principal amenaza para la ¿joya de la ganadería canaria¿: Necesidad de avances en diagnóstico, control y prevención en las Islas Canarias 
La Paratuberculosis (PTB} Caprina, principal amenaza para la ''joya de la ganadería canaria": Necesidad de avances en diagnóstico, control y prevención en las Islas Canarias 
Journal: Veterinary Sciences 
Abstract: Paratuberculosis (PTB), caused by Mycobacterium avium subspecies paratuberculosis (MAP), is a chronic disease with economic impact on ruminant farming worldwide. The Canary Islands count with the fourth largest goat population in Spain and are “officially free” of bovine tuberculosis. Twelve farms were included with 2774 serum samples tested by an enzyme-linked immunosorbent assay (ELISA) for detection of anti-MAP antibodies in two sessions. In the first session, an overall apparent prevalence of 18.4% (2.5% up to 61.1%) was obtained. Farms with prevalences (0–10%], (10–20%] and >20% were identified, with differences in seroconversion in the same prevalence group between farms and age ranges. Non-vaccinated (nV) and vaccinated (V) animals were included in the second sampling session. Higher levels of antibodies were detected in V animals older than 12 months, with considerable variations between age ranges and farms. Our results describe the current PTB status of the Canary Islands’ goat farming. Furthermore, new insights on the effect of the farm prevalence on seroconversion in V animals are provided, although further studies are needed to evaluate the multiple factors affecting the immune response to anti-MAP vaccination.
URI: http://hdl.handle.net/10553/133236
ISSN: 2306-7381
DOI: 10.3390/vetsci11090388
Source: Veterinary Sciences[ISSN2306-7381], v.11(9)
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