Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/130682
Title: Trophic Nutrition in ICU Patients Undergoing High-Flow Oxygen Therapy and/or Noninvasive Mechanical Ventilation: The Nutri-Trophic Study
Authors: Reta Pérez, Olivia 
Colmenero-Ruiz, Manuel
Hernández Socorro, Carmen Rosa 
Saavedra Santana, Pedro 
Maichle, Silmary F.
Portugal, Esther
Cerezo-Arias, Mariola
Sanchez Ales, Laura
Martinez-Carmona, Juan F.
Mateu-Campos, Lidon
Lorencio-Cardenas, Carol
Garcia-Miguelez, Ana
Sosa Durr, Maria
San Martin Bragado, Maria
Ruiz Santana, Sergio 
UNESCO Clasification: 32 Ciencias médicas
3206 Ciencias de la nutrición
Keywords: Critically-Ill Patients
Parenteral-Nutrition
Enteral Nutrition
Energy-Balance
Nasal Cannula, et al
Issue Date: 2024
Journal: Nutrients 
Abstract: Enteral nutrition (EN) therapy in ICU patients requiring oxygen therapy with high-flow nasal cannula (HFNC) and/or noninvasive mechanical ventilation (NIMV) is controversial. A prospective, cohort, observational, and multicenter study was conducted in 10 ICUs in Spain to analyze the 90-day mortality, tolerance, side effects, and infectious complications of trophic EN in patients requiring HFNC therapy and/or NIVM. A total of 149 patients were enrolled. The mean age, severity scores, tracheobronchitis, bacteremia, and antimicrobial therapy were significantly higher in deceased than in living patients (p < 0.05), and the mortality rate was 14.8%. A total of 110 patients received oral trophic feedings, 36 patients received nasogastric tube feedings (NGFs), and 3 received mixed feedings. Trophic EN was discontinued in only ten (14.9%) patients because of feeding-related complications. The variables selected for the multivariate logistic regression on feeding discontinuation were SOFA upon admission (OR per unit = 1.461) and urea (OR per mg/dL = 1.029). There were no significant differences in the development of new infections according to the route of EN administration. Early trophic feeding administered to patients with acute respiratory failure requiring noninvasive ventilation is safe and feasible, and is associated with few dietary and infectious complications in a mortality, setting comparable to similar studies.
URI: http://hdl.handle.net/10553/130682
ISSN: 2072-6643
DOI: 10.3390/nu16091366
Source: Nutrients[EISSN 2072-6643],v. 16 (9), (Abril 2024)
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