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http://hdl.handle.net/10553/129183
Title: | 2-Hydroxyethyl methacrylate (2-HEMA) sensitization, a global epidemic at its peak in Spain? | Authors: | Gatica-Ortega, Maria Elena Pastor-Nieto, Maria Antonia Giménez-Arnau, Ana María Mercader-García, Pedro Sanz-Sánchez, Tatiana Carrascosa-Carrillo, José Manuel Córdoba-Guijarro, Susana Sánchez Pérez, Javier Silvestre, Juan Francisco Frutos, Francisco Javier Ortiz de Tous-Romero, Fátima Fernández-Redondo, Virginia Serra-Baldrich, Esther Ruíz-González, Inmaculada González Pérez, Ricardo Miquel-Miquel, Javier Guillén, Paloma Sánchez Pedreño Hervella-García, Marcos Heras-Mendaza, Felipe Gómez-de-la-Fuente, Enrique Zaragoza-Ninet, Violeta Gilo, Araceli Sánchez Rodríguez-Serna, Mercedes Melé-Ninot, Gemma Descalzo, Miguel Ángel de-Vega, Marina García-Doval, Ignacio Borrego Hernando, Leopoldo |
UNESCO Clasification: | 32 Ciencias médicas 320106 Dermatología |
Keywords: | (Meth)Acrylates 2-Hydroxyethyl Methacrylate Acrylates Acrylic Nails Allergic Contact Dermatitis, et al |
Issue Date: | 2024 | Journal: | Contact Dermatitis | Abstract: | Background: A global epidemic of allergic contact dermatitis to (meth)acrylates has been described in relation to the widespread use of manicure products. Objectives: To evaluate the frequency of sensitization to 2-hydroxyethyl methacrylate (2-HEMA) among consecutively patch tested patients with eczema in Spain; the percentage of current relevance; the MOAHLFA index; and, the potential sources of exposure to (meth)acrylates. Methods: From January 2019 to December 2022, 2-HEMA 2% pet. was prospectively patch tested in 24 REIDAC (Spanish Allergic Contact Dermatitis Registry) centres. Results: Six thousand one hundred thirty-four patients were consecutively patch tested with 2-HEMA 2% pet. 265/6134 (4.3%) were positive. Positive reactions of current relevance were identified to involve 184/265 (69%). The efficiency (number of patch tests needed to detect relevant positive patch test reactions) was 34 (6134/184). The variable ‘occupational’ was found to be significantly associated with a higher risk for relevant positive reactions to 2-HEMA (OR: 10.9; 95% CI: 8.1–14.9). Conclusion: (Meth)acrylate sensitization is a prevalent health issue in Spain. 2-HEMA 2% pet. has been identified to be a highly effective (meth)acrylate allergy marker in the GEIDAC baseline series. The responsible authorities should implement policies guaranteeing accurate labelling of industrial, medical, and consumer materials while ensuring the enforcement of said labelling through appropriate legal means. | URI: | http://hdl.handle.net/10553/129183 | ISSN: | 0105-1873 | DOI: | 10.1111/cod.14520 | Source: | Contact Dermatitis[ISSN 0105-1873],p. 1-7 (Febrero 2024) |
Appears in Collections: | Artículos |
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