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Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/128720
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dc.contributor.authorMeersch, Melanieen_US
dc.contributor.authorWeiss, Raphaelen_US
dc.contributor.authorStrauß, Christianen_US
dc.contributor.authorAlbert, Felixen_US
dc.contributor.authorBooke, Hendriken_US
dc.contributor.authorForni, Luien_US
dc.contributor.authorPittet, Jean-Francoisen_US
dc.contributor.authorKellum, John A.en_US
dc.contributor.authorRosner, Mitchellen_US
dc.contributor.authorMehta, Ravindraen_US
dc.contributor.authorBellomo, Rinaldoen_US
dc.contributor.authorRosenberger, Peteren_US
dc.contributor.authorZarbock, Alexanderen_US
dc.contributor.authorMakhloufi, Hichemen_US
dc.contributor.authorSakhraoui, Rachidaen_US
dc.contributor.authorOuyahia, Amelen_US
dc.contributor.authorRais, Mouniraen_US
dc.contributor.authorKouicem, Aya Tinhinaneen_US
dc.contributor.authorDerwish, Khawlaen_US
dc.contributor.authorAbdoun, Meriemen_US
dc.contributor.authorOuahab, Ilhemen_US
dc.contributor.authorBouaoud, Souaden_US
dc.contributor.authorTidjane, Anisseen_US
dc.contributor.authorRivera, Carlos Jose Pérezen_US
dc.contributor.authorGarcía, Juan Pabloen_US
dc.contributor.authorPeng, Keen_US
dc.contributor.authorJi, Fu-haien_US
dc.contributor.authorMa, Zheng-minen_US
dc.contributor.authorElbahnasawy, Mohamed Gamalen_US
dc.contributor.authorElsalhawy, Shadyen_US
dc.contributor.authorNafea, Ahmed Mahmouden_US
dc.contributor.authorOsman, Nermin A.en_US
dc.contributor.authorEmara, Moataz Maheren_US
dc.contributor.authorBonna, Mohamed Mamdouhen_US
dc.contributor.authorAbdehaleem, Ibrahim Abdelmonaemen_US
dc.contributor.authorAbbas, Ahmed Mohameden_US
dc.contributor.authorAbbas, Mostafa Samyen_US
dc.contributor.authorEsmaeil, Hany Mostafaen_US
dc.contributor.authorJoannes-Boyau, Oliveren_US
dc.contributor.authorLegros, Vincenten_US
dc.contributor.authorFloch, Thierryen_US
dc.contributor.authorMuccio, Salvatoreen_US
dc.contributor.authorMenage-Innocenti, Lisonen_US
dc.contributor.authorBrochet, Benjaminen_US
dc.contributor.authorLeclercq-Rouget, Marionen_US
dc.contributor.authorGeneve, Claireen_US
dc.contributor.authorMocarquer, Bernardita Valenzuelaen_US
dc.contributor.authorAveline, Christopheen_US
dc.contributor.authorVautier, Pierreen_US
dc.contributor.authorNadaud, Julienen_US
dc.contributor.authorRimmelé, Thomasen_US
dc.contributor.authorCerro, Valérieen_US
dc.contributor.authorSuria, Stéphanieen_US
dc.contributor.authorElmawieh, Jamieen_US
dc.contributor.authorEl-Jawiche, Ritaen_US
dc.contributor.authorCirenei, Cédricen_US
dc.contributor.authorLebuffe, Gillesen_US
dc.contributor.authorPonsonnard, Sébastienen_US
dc.contributor.authorEgreteau, Pierre-Yvesen_US
dc.contributor.authorIchai, Caroleen_US
dc.contributor.authorJean-Michel, Vanessaen_US
dc.contributor.authorLéger, Maximeen_US
dc.contributor.authorLasocki, Sigismonden_US
dc.contributor.authorMasson, Charlineen_US
dc.contributor.authorRineau, Emmanuelen_US
dc.contributor.authorCassisa, Vivianeen_US
dc.contributor.authorVerrier, Pierreen_US
dc.contributor.authorAtchade, Enoraen_US
dc.contributor.authorRochon, Charles-Edouarden_US
dc.contributor.authorQuentin, Vidalen_US
dc.contributor.authorQueixalos, Ninaen_US
dc.contributor.authorBraun, Thierryen_US
dc.contributor.authorGrand, Huberten_US
dc.contributor.authorMayeur, Nicolasen_US
dc.contributor.authorPasquie, Marieen_US
dc.contributor.authorGarçon, Pierreen_US
dc.contributor.authorBruckert, Vincenten_US
dc.contributor.authorPradel, Gaëlen_US
dc.contributor.authorRamorasata, Andersenen_US
dc.contributor.authorRavry, Célineen_US
dc.contributor.authorMottard, Nicolasen_US
dc.contributor.authorZarbock, Alexanderen_US
dc.contributor.authorMeersch, Melanieen_US
dc.contributor.authorWeiss, Raphaelen_US
dc.contributor.authorvon Groote, Thiloen_US
dc.contributor.authorDörr, Christianen_US
dc.contributor.authorKüllmar, Miraen_US
dc.contributor.authorMassoth, Christinaen_US
dc.contributor.authorMotekallemi, Arashen_US
dc.contributor.authorSaadat-Gilani, Khaschayaren_US
dc.contributor.authorAlbert, Felixen_US
dc.contributor.authorKerschke, Lauraen_US
dc.contributor.authorStorck, Michaelen_US
dc.contributor.authorVarghese, Julianen_US
dc.contributor.authorWempe, Carolaen_US
dc.contributor.authorGrüßer, Lindaen_US
dc.contributor.authorKowark, Anaen_US
dc.contributor.authorBrandenburger, Timoen_US
dc.contributor.authorHohn, Andreasen_US
dc.contributor.authorRosenberger, Peteren_US
dc.contributor.authorHäberle, Heleneen_US
dc.contributor.authorHofmann, Pascalen_US
dc.contributor.authorKuhle, Jonathanen_US
dc.contributor.authorCalov, Stefanieen_US
dc.contributor.authorBernard, Alice Marieen_US
dc.contributor.authorMirakaj, Valbonaen_US
dc.contributor.authorWeber, Kathrinen_US
dc.contributor.authorPfister, Kathrinen_US
dc.contributor.authorStetz, Lenaen_US
dc.contributor.authorMüller, Sarah Dorotheaen_US
dc.contributor.authorKlaus, Stephanen_US
dc.contributor.authorSadlo, Marcoen_US
dc.contributor.authorSengelhoff, Christianen_US
dc.contributor.authorStenger, Carina-Kristinen_US
dc.contributor.authorGöbel, Ulrichen_US
dc.contributor.authorHeringlake, Matthiasen_US
dc.contributor.authorArnaoutoglou, Elenien_US
dc.contributor.authorStratigopoulou, Panagiotaen_US
dc.contributor.authorDanai, Pantazien_US
dc.contributor.authorDimakopoulou, Antoniaen_US
dc.contributor.authorMenis, Apostolos-Alkiviadisen_US
dc.contributor.authorIoannidis, Orestisen_US
dc.contributor.authorJalaawiy, Humamen_US
dc.contributor.authorAnwar, Aeshahen_US
dc.contributor.authorHashim, Hashim Taliben_US
dc.contributor.authorAldawoody, Hogir Imad Rasheeden_US
dc.contributor.authorCortegiani, Andreaen_US
dc.contributor.authorIppolito, Mariachiaraen_US
dc.contributor.authorMarino, Claudiaen_US
dc.contributor.authorPresti, Gabrieleen_US
dc.contributor.authorFricano, Dario Calogeroen_US
dc.contributor.authorDe Rosa, Silviaen_US
dc.contributor.authorBianchin, Andreaen_US
dc.contributor.authorPaternoster, Gianlucaen_US
dc.contributor.authorFasciano, Umbertoen_US
dc.contributor.authorCutuli, Salvatore Lucioen_US
dc.contributor.authorSavino, Spadaroen_US
dc.contributor.authorEnrico, Bussolatien_US
dc.contributor.authorMarco, Palmierien_US
dc.contributor.authorAlberto, Volta Carloen_US
dc.contributor.authorTripodi, Vincenzo Francescoen_US
dc.contributor.authorFiume, Diegoen_US
dc.contributor.authorIuorio, Angelaen_US
dc.contributor.authorSantorsola, Clementeen_US
dc.contributor.authorAbu-Hussein, Bilalen_US
dc.contributor.authorHasanein, Khaleden_US
dc.contributor.authorShin, Seokyungen_US
dc.contributor.authorBaek, Jongyoonen_US
dc.contributor.authorKim, Sehuien_US
dc.contributor.authorElhadi, Muhammeden_US
dc.contributor.authorAldressi, Wafaen_US
dc.contributor.authorAbuzeid, Issa A.en_US
dc.contributor.authorAlbaraesi, Mohammed N.en_US
dc.contributor.authorMoftah, Mohamed Azizen_US
dc.contributor.authorAldressi, Sarahen_US
dc.contributor.authorKhalel, Wegdanen_US
dc.contributor.authorAbdulwahed, Emanen_US
dc.contributor.authorAlshareea, Entisar Ahmed Alien_US
dc.contributor.authorAbujrad, Akram Abdulhamid Ashuren_US
dc.contributor.authorGhmagh, Reemen_US
dc.contributor.authorBiala, Marwa Isaen_US
dc.contributor.authorDerwish, Khawlaen_US
dc.contributor.authorAl Islam Benjouira, Rayeten_US
dc.contributor.authorAliwa, Mohameden_US
dc.contributor.authorMsherghi, Ahmeden_US
dc.contributor.authorTuwaib, Ahmeden_US
dc.contributor.authorMustafa, Tahanien_US
dc.contributor.authorZriba, Haifaen_US
dc.contributor.authorAgilla, Hamza Mahmouden_US
dc.contributor.authorHamida, Bahaeddin Taher Sadek Benen_US
dc.contributor.authorOtman, Rema Hassan Mohameden_US
dc.contributor.authorMijovska, Maja Mojsovaen_US
dc.contributor.authorPodesta, Anne Marie Camillerien_US
dc.contributor.authorLópez, Gilberto Adrián Gascaen_US
dc.contributor.authorAmro, Sarahen_US
dc.contributor.authorde Freitas Regufe, Ritaen_US
dc.contributor.authorGrigoryev, Evgenyen_US
dc.contributor.authorIvkin, Artemen_US
dc.contributor.authorBalakhnin, Dmitriyen_US
dc.contributor.authorShukevich, Dmitriyen_US
dc.contributor.authorYaroustovsky, Michaelen_US
dc.contributor.authorBarmou, Abdulnaseren_US
dc.contributor.authorKaserer, Alexanderen_US
dc.contributor.authorCastellucci, Claraen_US
dc.contributor.authorAkbas, Samiraen_US
dc.contributor.authorPetrun, Andreja Mölleren_US
dc.contributor.authorGregorcic, Irenaen_US
dc.contributor.authorSok, Vesnaen_US
dc.contributor.authorLinks, Andreen_US
dc.contributor.authorBarreto, Elizabeth Bárcenaen_US
dc.contributor.authorMelchor, Javier Ripollésen_US
dc.contributor.authorBecerra Bolaños, Ángelen_US
dc.contributor.authorRodríguez Pérez, Aurelio Eduardoen_US
dc.contributor.authorEstévez, Javier Mataen_US
dc.contributor.authorMatas, Juan Muleten_US
dc.contributor.authorPalao, Sara Pérezen_US
dc.contributor.authorÁlvarez, Mercedes Garcíaen_US
dc.contributor.authorAlbadalejo, Albert Bainacen_US
dc.contributor.authorGonzález, Astrid Batallaen_US
dc.contributor.authorCaro, Ana María Gómezen_US
dc.contributor.authorBlanco, Ignacio Hinojalen_US
dc.contributor.authorFernandez, Diego Toralen_US
dc.contributor.authorPerez, Gracia Herranzen_US
dc.contributor.authorEjea, Margarita Logroñoen_US
dc.contributor.authorde la Rosa Ruiz, Noeliaen_US
dc.contributor.authorAbasolo, María Gastacaen_US
dc.contributor.authorFerreira, Lourdesen_US
dc.contributor.authorLobato, Félixen_US
dc.contributor.authorSevilla, Marta Aguadoen_US
dc.contributor.authorErazo, Andresen_US
dc.contributor.authorPaulis, Berta Castellanoen_US
dc.contributor.authorde la Calle Gil, Isabelen_US
dc.contributor.authorAdamove, Peteren_US
dc.contributor.authorBlasco Blasco, Francho Miguelen_US
dc.contributor.authorGarcía-Sánchez, Jose Ignacioen_US
dc.contributor.authorZamorano, Sara Garcíaen_US
dc.contributor.authorHerreros, Natalia Gijónen_US
dc.contributor.authorCallejas, Raquelen_US
dc.contributor.authorGómez, Mercedes Estaireen_US
dc.contributor.authorCandela-Toha, Angel M.en_US
dc.contributor.authorClaros-Llamas, Elisabethen_US
dc.contributor.authorCobeta-Orduña, Pilaren_US
dc.contributor.authorCrespo-Aliseda, Pascualen_US
dc.contributor.authorDorado-Díaz, Trinidaden_US
dc.contributor.authorGómez-Rojo, Maríaen_US
dc.contributor.authorMané-Ruiz, M. Nuriaen_US
dc.contributor.authorMartín-González, M. Carmenen_US
dc.contributor.authorMartínez-Pérez, Adolfoen_US
dc.contributor.authorTiscar, Carlosen_US
dc.contributor.authorMenéndez, Patricia Galánen_US
dc.contributor.authorCalvo, Verónica Estepaen_US
dc.contributor.authorEspí, Laura Llinaresen_US
dc.contributor.authorAldeán, Yuri Santiago Loaizaen_US
dc.contributor.authorAriza, Víctor Moralesen_US
dc.contributor.authorVila, Laura Villarinoen_US
dc.contributor.authorGarcía-Miguel, Francisco Javieren_US
dc.contributor.authorSuliman, Elfayadh S. M.en_US
dc.contributor.authorIbrahim, Ahmed Mohameden_US
dc.contributor.authorFadlalmola, Hammad Ali.en_US
dc.contributor.authorSwed, Saryaen_US
dc.contributor.authorWu, Vin-Centen_US
dc.contributor.authorOrhan-Sungur, Mukadderen_US
dc.contributor.authorAltun, Demeten_US
dc.contributor.authorCanbolat, Nuren_US
dc.contributor.authorDinçer, Müşerref Berilen_US
dc.contributor.authorYildirim, Serap Aktasen_US
dc.contributor.authorIyigun, Muzeyyenen_US
dc.contributor.authorYapıcı, Davuden_US
dc.contributor.authorÖzdemir, Leventen_US
dc.contributor.authorSagün, Aslınuren_US
dc.contributor.authorBoztug, Nevalen_US
dc.contributor.authorGündüz, Emelen_US
dc.contributor.authorLafli-Tunay, Demeten_US
dc.contributor.authorKarakaya, Denizen_US
dc.contributor.authorDost, Burhanen_US
dc.contributor.authorKomurcu, Ozguren_US
dc.contributor.authorDilmen, Ozlem Korkmazen_US
dc.contributor.authorAkcil, Eren Fatmaen_US
dc.contributor.authorTunali, Yusufen_US
dc.contributor.authorOk, Gulayen_US
dc.contributor.authorTok-Alsina, Edaen_US
dc.contributor.authorPolat, Cengizen_US
dc.contributor.authorKızılcık, Nurcanen_US
dc.contributor.authorŞen, Öznuren_US
dc.contributor.authorDarçın, Kamilen_US
dc.contributor.authorUğur, Semraen_US
dc.contributor.authorGürkan, Yavuzen_US
dc.contributor.authorSaracoglu, Kemal Tolgaen_US
dc.contributor.authorYıldız-Koyuncu, Özgeen_US
dc.contributor.authorDemir, Z. Aslıen_US
dc.contributor.authorPostacı, N. Aysunen_US
dc.contributor.authorÖzgök, Ayşegülen_US
dc.contributor.authorKaradeniz, Ümiten_US
dc.contributor.authorÖzay, Hülya Yiğiten_US
dc.contributor.authorBalcı, Edaen_US
dc.contributor.authorSalman, Nevriyeen_US
dc.contributor.authorGirgin, Behiçen_US
dc.contributor.authorSagir, Ozlemen_US
dc.contributor.authorDemir, Hafize Fisunen_US
dc.contributor.authorUgun, Fatihen_US
dc.contributor.authorToprak, Hüseyin İlksenen_US
dc.contributor.authorÖzcan, Mustafa Soneren_US
dc.contributor.authorAlkaya-Solmaz, Filizen_US
dc.contributor.authorYilmaz, Mehmeten_US
dc.contributor.authorKaraca, Umranen_US
dc.contributor.authorŞahin, Sevtap Hekimogluen_US
dc.contributor.authorErkoç, Süheyla Karadağen_US
dc.contributor.authorAlkış, Neslihanen_US
dc.contributor.authorBaytaş, Volkanen_US
dc.contributor.authorErturk, Enginen_US
dc.contributor.authorSaylan, Sedaten_US
dc.contributor.authorAkdogan, Alien_US
dc.contributor.authorYeşil, Beyza Büyükgebizen_US
dc.contributor.authorBoran, Omer Faruken_US
dc.contributor.authorOrak, Yavuzen_US
dc.contributor.authorÇalişir, Feyzaen_US
dc.contributor.authorBüyükçoban, Sibelen_US
dc.contributor.authorKuvaki, Baharen_US
dc.contributor.authorCansabuncu, Sedaen_US
dc.contributor.authorAkesen, Selcanen_US
dc.contributor.authorGören, Sunaen_US
dc.contributor.authorYeniocak, Tugceen_US
dc.contributor.authorOrman, Osmanen_US
dc.contributor.authorKarka, Özlem Ersoyen_US
dc.contributor.authorSahin, Tulayen_US
dc.contributor.authorMomot, Nataliaen_US
dc.contributor.authorPanchenko, Annaen_US
dc.contributor.authorPittet, Jean-Francoisen_US
dc.contributor.authorRutledge, Kristenen_US
dc.date.accessioned2024-01-29T20:03:40Z-
dc.date.available2024-01-29T20:03:40Z-
dc.date.issued2024en_US
dc.identifier.issn0342-4642en_US
dc.identifier.urihttp://hdl.handle.net/10553/128720-
dc.description.abstractPurpose Acute kidney disease (AKD) is a significant health care burden worldwide. However, little is known about this complication after major surgery. Methods We conducted an international prospective, observational, multi-center study among patients undergoing major surgery. The primary study endpoint was the incidence of AKD (defined as new onset of estimated glomerular filtration rate (eCFR) < 60 ml/min/1.73 m2 present on day 7 or later) among survivors. Secondary endpoints included the relationship between early postoperative acute kidney injury (AKI) (within 72 h after major surgery) and subsequent AKD, the identification of risk factors for AKD, and the rate of chronic kidney disease (CKD) progression in patients with pre-existing CKD. Results We studied 9510 patients without pre-existing CKD. Of these, 940 (9.9%) developed AKD after 7 days of whom 34.1% experiencing an episode of early postoperative-AKI. Rates of AKD after 7 days significantly increased with the severity (19.1% Kidney Disease Improving Global Outcomes [KDIGO] 1, 24.5% KDIGO2, 34.3% KDIGO3; P < 0.001) and duration (15.5% transient vs 38.3% persistent AKI; P < 0.001) of early postoperative-AKI. Independent risk factors for AKD included early postoperative-AKI, exposure to perioperative nephrotoxic agents, and postoperative pneumonia. Early postoperative-AKI carried an independent odds ratio for AKD of 2.64 (95% confidence interval [CI] 2.21–3.15). Of 663 patients with pre-existing CKD, 42 (6.3%) had worsening CKD at day 90. In patients with CKD and an episode of early AKI, CKD progression occurred in 11.6%. Conclusion One in ten major surgery patients developed AKD beyond 7 days after surgery, in most cases without an episode of early postoperative-AKI. However, early postoperative-AKI severity and duration were associated with an increased rate of AKD and early postoperative-AKI was strongly associated with AKD independent of all other potential risk factors.en_US
dc.languageengen_US
dc.relation.ispartofIntensive Care Medicineen_US
dc.sourceIntensive Care Medicine [0342-4642] (Enero 2024)en_US
dc.subject32 Ciencias médicasen_US
dc.subject320506 Nefrologíaen_US
dc.subject3213 Cirugíaen_US
dc.subject.otherAcute kidney diseaseen_US
dc.subject.otherAcute kidney injuryen_US
dc.subject.otherChronic kidney diseaseen_US
dc.subject.otherSurgeryen_US
dc.subject.otherPostoperativeen_US
dc.titleAcute kidney disease beyond day 7 after major surgery: a secondary analysis of the EPIS-AKI trialen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1007/s00134-023-07314-2en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.description.numberofpages11en_US
dc.utils.revisionSíen_US
dc.date.coverdateEnero 2024en_US
dc.identifier.ulpgcSíen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr6,232
dc.description.jcr29,6
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
dc.description.miaricds11,0
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.deptGIR IUSA-ONEHEALTH 5: Reproducción Animal, Oncología y Anestesiología Comparadas-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0002-2817-3144-
crisitem.author.orcid0000-0003-0947-263X-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.fullNameBecerra Bolaños, Ángel-
crisitem.author.fullNameRodríguez Pérez, Aurelio Eduardo-
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