Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/127023
Campo DC Valoridioma
dc.contributor.authorNavarro Santana, Beatriz Fátimaen_US
dc.contributor.authorGarcia Torralba, Esmeraldaen_US
dc.contributor.authorViveros Carreño, Daviden_US
dc.contributor.authorRodriguez, Julianaen_US
dc.contributor.authorPareja, Reneen_US
dc.contributor.authorMartín Martínez, Aliciaen_US
dc.contributor.authorForte, Saraen_US
dc.contributor.authorKrause, Kate J.en_US
dc.contributor.authorGonzález-Martín, J. M.en_US
dc.contributor.authorRamirez, Pedro T.en_US
dc.date.accessioned2023-10-02T12:13:28Z-
dc.date.available2023-10-02T12:13:28Z-
dc.date.issued2023en_US
dc.identifier.issn1048-891Xen_US
dc.identifier.otherScopus-
dc.identifier.urihttp://hdl.handle.net/10553/127023-
dc.description.abstractObjective: Cytoreductive surgery in conjunction with hyperthermic intraperitoneal chemotherapy (HIPEC) is being explored in the upfront, interval, and recurrent setting in patients with ovarian cancer. The objective of this systematic review was to assess the rate of complications associated with HIPEC in epithelial ovarian cancer surgery over two time periods. Methods: This study was registered in PROSPERO (CRD42022328928). A systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist. Ovid/Medline, Ovid/Embase, Web of Science, Scopus, and Cochrane Central Register of Controlled Trials were searched from January 2004 to April 2022. We included studies reporting on patients with advanced primary or recurrent epithelial ovarian cancer who underwent cytoreductive surgery and HIPEC. We evaluated two different time periods: 2004-2013 and 2014-2022. A random-effects meta-analysis was used to produce an overall summary. Subgroup analyses were planned according to recruited period for each specific complication type. Heterogeneity was assessed using the I2 statistic. Results: A total of 4928 patients were included from 69 studies for this systematic review; 19 published from 2004-2013, and 50 published from 2014-2022. No significant differences were found between the two time periods in terms of blood transfusions (33% vs 51%; p=0.46; I2=95%) overall gastrointestinal complications (15% vs 21%; p=0.36; I2=98%), infectious diseases (16% vs 13%; p=0.62; I2=93%), overall respiratory complications (12% vs 12%; p=0.88; I2=91%), overall urinary complications (6% vs 12%; p=0.06; I2=94%), or thromboembolic events (5% vs 3%; p=0.25; I2=63%). Also, no differences were found in intensive care unit (ICU) admissions (89% vs 28%; p=0.06; I2=99%), reoperations (8% vs 7%; p=0.50; I2=37%), or deaths (3% vs 3%; p=0.77; I2=57%). Conclusions: Our review showed that overall complications have not changed over time for patients undergoing HIPEC in the setting of primary or recurrent ovarian cancer. There was no decrease in the rates of ICU admissions, reoperations, or deaths.en_US
dc.languageengen_US
dc.relation.ispartofInternational Journal of Gynecological Canceren_US
dc.sourceInternational Journal of Gynecological Cancer [ISSN 1048-891X], (Enero 2023)en_US
dc.subject320101 Oncologíaen_US
dc.subject320108 Ginecologíaen_US
dc.subject3213 Cirugíaen_US
dc.subject.otherOvarian Neoplasmsen_US
dc.subject.otherPostoperative Complicationsen_US
dc.titleComplications of HIPEC for ovarian cancer surgery: Evaluation over two time periodsen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1136/ijgc-2023-004658en_US
dc.identifier.scopus85171757918-
dc.contributor.orcid0000-0002-5572-7843-
dc.contributor.orcidNO DATA-
dc.contributor.orcid0000-0001-9395-0627-
dc.contributor.orcid0000-0002-5472-4093-
dc.contributor.orcid0000-0003-0093-0438-
dc.contributor.orcidNO DATA-
dc.contributor.orcid0000-0002-0499-8299-
dc.contributor.orcidNO DATA-
dc.contributor.orcidNO DATA-
dc.contributor.orcid0000-0002-6370-8052-
dc.contributor.authorscopusid57008312000-
dc.contributor.authorscopusid57211856820-
dc.contributor.authorscopusid56191578300-
dc.contributor.authorscopusid57202920099-
dc.contributor.authorscopusid24923187800-
dc.contributor.authorscopusid58418023700-
dc.contributor.authorscopusid57203635689-
dc.contributor.authorscopusid57195385733-
dc.contributor.authorscopusid57203435427-
dc.contributor.authorscopusid7103197264-
dc.identifier.eissn1525-1438-
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.utils.revisionen_US
dc.date.coverdateEnero 2023en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr1,107
dc.description.jcr4,8
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
dc.description.miaricds11,0
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcidhttps://orcid.org/0000-0002-5572-7843-
crisitem.author.orcid0000-0002-4237-6378-
crisitem.author.fullNameNavarro Santana, Beatriz Fátima-
crisitem.author.fullNameMartín Martínez, Alicia-
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