Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/123256
Title: Morphological Assessment of Concomitant Lesions Detected in Goat Herds Naturally Infected with Paratuberculosis (Johne’s Disease)
Authors: Stefanova, Elena Plamenova 
Quesada Canales, Ildefonso Óscar 
Paz Sanchez,Yania 
Caballero Cansino, María José 
Quintana Montesdeoca, María Del Pino 
Espinosa De Los Monteros Y Zayas, Antonio 
Rivero Santana, Miguel Antonio 
Castro Alonso, Ayoze 
Pérez, Valentín
Andrada Borzollino, Marisa Ana 
UNESCO Clasification: 3109 Ciencias veterinarias
310907 Patología
Keywords: Concomitant Pathologies
Goat Pathology
Histopathology
Lesions
Mycobacterium Avium Subspecies Paratuberculosis, et al
Issue Date: 2023
Journal: Animal 
Abstract: Paratuberculosis (PTB), caused by Mycobacterium avium subspecies paratuberculosis (MAP), causes significant financial losses in the ruminant industry. The aim of this study is to describe the concomitant pathological findings as well as PTB-induced lesions in 39 naturally infected goats (15 vaccinated and 24 non-vaccinated). All animals exhibited MAP-induced microscopic lesions affecting target organs, although only 62% of those were detected grossly. Mainly concomitant inflammatory pathologies were recognized affecting the hemolymphatic, respiratory and gastrointestinal systems. Non-vaccinated animals exhibited both moderate and marked granulomatous enteritis in contrast with vaccinated ones which presented mild intestinal affection. Our results demonstrate that non-vaccinated animals presented pneumonia in all age groups studied (from 12 up to >48 months old). A significantly higher prevalence of ileocecal valve PTB lesions was detected in non-vaccinated animals with pneumonic lesions (p = 0.027). Furthermore, a reduction of gastrointestinal non-PTB processes was described in vaccinated goats. In conclusion, a PTB infected goat herd can be affected by a wide range of concomitant pathologies, mostly inflammatory in origin. Anatomic pathology is of crucial importance for correct herd diagnosis and histopathology is an indispensable tool for lesion detection. Additionally, anti-MAP vaccination could have a beneficial effect on the reduction of respiratory and gastrointestinal non-PTB diseases.
URI: http://hdl.handle.net/10553/123256
ISSN: 2076-2615
DOI: 10.3390/ani13101693
Source: Animals[EISSN 2076-2615],v. 13 (10):1693, (Mayo 2023)
Appears in Collections:Artículos
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