Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/119526
Title: | Genetics and Nutrition Drive the Gut Microbiota Succession and Host-Transcriptome Interactions through the Gilthead Sea Bream (Sparus aurata) Production Cycle | Authors: | Naya-Catalá, Fernando Piazzon, Carla Torrecillas Burriel,Silvia Toxqui-rodriguez, Socorro Calduch-Giner, Josep A. Fontanillas, Ramon Sitjà-Bobadilla, Ariadna Montero Vítores, Daniel Pérez-Sánchez, Jaume |
UNESCO Clasification: | 310502 Piscicultura 240991 Genética del desarrollo 310406 Nutrición |
Keywords: | Sea bream Selective breeding Nutrition Gut microbiota Host transcriptomics, et al |
Issue Date: | 2022 | Project: | Genomic and nutritional innovations for genetically superior farmed fish to improve efficiency in European aquaculture | Journal: | Biology | Abstract: | Fish genetically selected for growth (GS) and reference (REF) fish were fed with CTRL (15% FM, 5–7% FO) or FUTURE (7.5% FM, 10% poultry meal, 2.2% poultry oil + 2.5% DHA-algae oil) diets during a 12-months production cycle. Samples from initial (t0; November 2019), intermediate (t1; July 2020) and final (t2; November 2020) sampling points were used for Illumina 16S rRNA gene amplicon sequencing of the adherent microbiota of anterior intestine (AI). Samples from the same individuals (t1) were also used for the gene expression profiling of AI by RNA-seq, and subsequent correlation analyses with microbiota abundances. Discriminant analyses indicated the gut bacterial succession along the production cycle with the proliferation of some valuable taxa for facing seasonality and different developmental stages. An effect of genetic background was evidenced along time, decreasing through the progression of the trial, namely the gut microbiota of GS fish was less influenced by changes in diet composition. At the same time, these fish showed wider transcriptomic landmarks in the AI to cope with these changes. Our results highlighted an enhanced intestinal sphingolipid and phospholipid metabolism, epithelial turnover and intestinal motility in GS fish, which would favour their improved performance despite the lack of association with changes in gut microbiota composition. Furthermore, in GS fish, correlation analyses supported the involvement of different taxa with the down-regulated expression of pro-inflammatory markers and the boosting of markers of extracellular remodelling and response to bacterium. Altogether, these findings support the combined action of the gut microbiome and host transcriptionally mediated effects to preserve and improve gut health and function in a scenario of different growth performance and potentiality. | URI: | http://hdl.handle.net/10553/119526 | ISSN: | 2079-7737 | DOI: | 10.3390/biology11121744 | Source: | Biology [ISSN 2079-7737], v. 11 (12) |
Appears in Collections: | Artículos |
WEB OF SCIENCETM
Citations
14
checked on Dec 8, 2024
Page view(s)
92
checked on Oct 6, 2024
Download(s)
64
checked on Oct 6, 2024
Google ScholarTM
Check
Altmetric
Share
Export metadata
Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.