Please use this identifier to cite or link to this item:
Title: Budd-Chiari-like pathology in dolphins
Authors: Fernández Rodríguez, Antonio Jesús 
Jepson, Paul D.
Diaz Delgado, Josue 
Bernaldo De Quirós Miranda, Yara 
Sierra Pulpillo, Eva María 
Mompeó Corredera, Blanca Rosa 
Vela, Ana Isabel
Di Guardo, Giovanni 
Suarez Santana, Cristian Manuel 
Espinosa De Los Monteros Y Zayas, Antonio 
Herráez Thomas, Pedro Manuel 
Andrada Borzollino, Marisa Ana 
Caballero Cansino, María José 
Rivero Santana, Miguel Antonio 
Consoli ,Francesco Mª Achille 
Castro Alonso, Ayoze 
Quesada Canales, Ildefonso Óscar 
Arbelo Hernández, Manuel Antonio 
UNESCO Clasification: 310907 Patología
Issue Date: 2022
Project: Patologia Embolica " Gaseosa / Grasa " en Cetaceos 
Journal: Scientific Reports 
Abstract: Nearly two decades ago, pathologic examination results suggested that acoustic factors, such as mid-frequency active naval military sonar (MFAS) could be the cause of acute decompression-like sickness in stranded beaked whales. Acute systemic gas embolism in these whales was reported together with enigmatic cystic liver lesions (CLL), characterized by intrahepatic encapsulated gas-filled cysts, tentatively interpreted as “gas-bubble” lesions in various other cetacean species. Here we provide a pathologic reinterpretation of CLL in odontocetes. Among 1,200 cetaceans necropsied, CLL were only observed in four striped dolphins (Stenella coeruleoalba), with a low prevalence (2%, N = 179). Together, our data strongly suggest that CLL are the result of the combination of a pre-existing or concomitant hepatic vascular disorder superimposed and exacerbated by gas bubbles, and clearly differ from acute systemic gas embolism in stranded beaked whales that is linked to MFAS. Budd-Chiari-like syndrome in dolphins is hypothesized based on the present pathologic findings. Nonetheless, further researched is warranted to determine precise etiopathogenesis(es) and contributing factors for CLL in cetaceans.
ISSN: 2045-2322
DOI: 10.1038/s41598-022-16947-0
Source: Scientific Reports [ISSN 2045-2322], v. 12, 12635, (2022)
Appears in Collections:Artículos
Adobe PDF (2,61 MB)
Show full item record

Google ScholarTM




Export metadata

Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.