Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/118738
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Fanjul Rodríguez, Luisa Fernanda | en_US |
dc.contributor.author | Gonzalez, J. | en_US |
dc.contributor.author | Saavedra Santana, Pedro | en_US |
dc.contributor.author | Estévez Rosas, Francisco Jesús | en_US |
dc.contributor.author | Quintana, J. | en_US |
dc.contributor.author | Ruiz De Galarreta Hernandez,C. Manuel | en_US |
dc.contributor.other | Estevez, Francisco | - |
dc.contributor.other | Quintana, Jose | - |
dc.date.accessioned | 2018-11-24T17:11:04Z | - |
dc.date.accessioned | 2022-10-03T13:48:25Z | - |
dc.date.available | 2018-11-24T17:11:04Z | - |
dc.date.available | 2022-10-03T13:48:25Z | - |
dc.date.issued | 1992 | en_US |
dc.identifier.issn | 0034-9402 | en_US |
dc.description.abstract | Progesterone biosynthesis and metabolization to 20alpha-hydroxyprogesterone was stimulated in granulosa cells cultured in the presence of 20 ng/ml of follicle stimulating hormone (FSH) or increasing concentrations of PGE2 (10(-9)-10(-7) M). Concurrent treatment with the synthetic progestin R5020 (10(-6) M) enhanced the FSH or PGE2 stimulated progesterone and 20alpha-hydroxyprogesterone accumulation in culture media, as well as DELTA5-3beta-hydroxysteroid dehydrogenase activity in granulosa cell homogenates. These findings may represent another example of an autocrine control mechanism in which the steroidogenic product of the granulosa cell exerts an ultra-short loop regulation of its own production. | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | Revista Espanola de Fisiologia | en_US |
dc.source | Revista Espanola De Fisiologia[ISSN 0034-9402],v. 48 (3), p. 167-170 (Diciembre 1992) | en_US |
dc.subject | 32 Ciencias médicas | en_US |
dc.subject | 320102 Genética clínica | en_US |
dc.subject.other | Steroidogenesis | en_US |
dc.subject.other | Granulosa cells | en_US |
dc.subject.other | Rat | en_US |
dc.subject.other | Human Chorionic-Gonadotropin | en_US |
dc.subject.other | Progesterone Production | en_US |
dc.subject.other | Preovulatory Follicles | en_US |
dc.subject.other | Plasminogen-Activator | en_US |
dc.subject.other | Luteinizing-Hormone | en_US |
dc.subject.other | Perfused Invitro | en_US |
dc.subject.other | Ovulation | en_US |
dc.subject.other | Prostaglandin | en_US |
dc.subject.other | Inhibitor | en_US |
dc.title | R5020 enhances PGE2 stimulated steroidogenesis in cultured rat granulosa cells | en_US |
dc.type | info:eu-repo/semantics/article | en_US |
dc.type | Article | en_US |
dc.identifier.pmid | 1301631 | - |
dc.identifier.scopus | 2-s2.0-0027008738 | - |
dc.identifier.isi | A1992KP57300004 | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dcterms.isPartOf | Revista Espanola De Fisiologia | - |
dcterms.source | Revista Espanola De Fisiologia[ISSN 0034-9402],v. 48 (3), p. 167-170 | - |
dc.contributor.authorscopusid | 7004158812 | - |
dc.contributor.authorscopusid | 57198495832 | - |
dc.contributor.authorscopusid | 7003526778 | - |
dc.contributor.authorscopusid | 7003810011 | - |
dc.contributor.authorscopusid | 8681043500 | - |
dc.contributor.authorscopusid | 7003806034 | - |
dc.description.lastpage | 170 | en_US |
dc.identifier.issue | 3 | - |
dc.description.firstpage | 167 | en_US |
dc.relation.volume | 48 | en_US |
dc.investigacion | Ciencias de la Salud | en_US |
dc.type2 | Artículo | en_US |
dc.identifier.wos | WOS:A1992KP57300004 | - |
dc.contributor.daisngid | 1127140 | - |
dc.contributor.daisngid | 16700767 | - |
dc.contributor.daisngid | 32482890 | - |
dc.contributor.daisngid | 329218 | - |
dc.contributor.daisngid | 30844495 | - |
dc.contributor.daisngid | 384944 | - |
dc.contributor.daisngid | 128315 | - |
dc.contributor.daisngid | 1664323 | - |
dc.identifier.investigatorRID | K-5125-2014 | - |
dc.identifier.investigatorRID | K-5709-2014 | - |
dc.description.numberofpages | 4 | en_US |
dc.utils.revision | Sí | en_US |
dc.contributor.wosstandard | WOS:FANJUL, LF | - |
dc.contributor.wosstandard | WOS:GONZALEZ, J | - |
dc.contributor.wosstandard | WOS:SANTANA, P | - |
dc.contributor.wosstandard | WOS:ESTEVEZ, F | - |
dc.contributor.wosstandard | WOS:QUINTANA, J | - |
dc.contributor.wosstandard | WOS:DEGALARRETA, CMR | - |
dc.date.coverdate | Diciembre 1992 | en_US |
dc.identifier.ulpgc | Sí | en_US |
dc.contributor.buulpgc | BU-MED | en_US |
item.grantfulltext | none | - |
item.fulltext | Sin texto completo | - |
crisitem.author.dept | Departamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología | - |
crisitem.author.dept | GIR Estadística | - |
crisitem.author.dept | Departamento de Matemáticas | - |
crisitem.author.dept | GIR IUIBS: Bioquímica | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología | - |
crisitem.author.orcid | 0009-0000-1982-055X | - |
crisitem.author.orcid | 0000-0003-1681-7165 | - |
crisitem.author.orcid | 0000-0002-9728-2774 | - |
crisitem.author.parentorg | Departamento de Matemáticas | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.fullName | Fanjul Rodríguez, Luisa Fernanda | - |
crisitem.author.fullName | Saavedra Santana, Pedro | - |
crisitem.author.fullName | Estévez Rosas, Francisco Jesús | - |
crisitem.author.fullName | Ruiz De Galarreta Hernandez,C. Manuel | - |
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