Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/118738
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dc.contributor.authorFanjul Rodríguez, Luisa Fernandaen_US
dc.contributor.authorGonzalez, J.en_US
dc.contributor.authorSaavedra Santana, Pedroen_US
dc.contributor.authorEstévez Rosas, Francisco Jesúsen_US
dc.contributor.authorQuintana, J.en_US
dc.contributor.authorRuiz De Galarreta Hernandez,C. Manuelen_US
dc.contributor.otherEstevez, Francisco-
dc.contributor.otherQuintana, Jose-
dc.date.accessioned2018-11-24T17:11:04Z-
dc.date.accessioned2022-10-03T13:48:25Z-
dc.date.available2018-11-24T17:11:04Z-
dc.date.available2022-10-03T13:48:25Z-
dc.date.issued1992en_US
dc.identifier.issn0034-9402en_US
dc.description.abstractProgesterone biosynthesis and metabolization to 20alpha-hydroxyprogesterone was stimulated in granulosa cells cultured in the presence of 20 ng/ml of follicle stimulating hormone (FSH) or increasing concentrations of PGE2 (10(-9)-10(-7) M). Concurrent treatment with the synthetic progestin R5020 (10(-6) M) enhanced the FSH or PGE2 stimulated progesterone and 20alpha-hydroxyprogesterone accumulation in culture media, as well as DELTA5-3beta-hydroxysteroid dehydrogenase activity in granulosa cell homogenates. These findings may represent another example of an autocrine control mechanism in which the steroidogenic product of the granulosa cell exerts an ultra-short loop regulation of its own production.en_US
dc.languageengen_US
dc.relation.ispartofRevista Espanola de Fisiologiaen_US
dc.sourceRevista Espanola De Fisiologia[ISSN 0034-9402],v. 48 (3), p. 167-170 (Diciembre 1992)en_US
dc.subject32 Ciencias médicasen_US
dc.subject320102 Genética clínicaen_US
dc.subject.otherSteroidogenesisen_US
dc.subject.otherGranulosa cellsen_US
dc.subject.otherRaten_US
dc.subject.otherHuman Chorionic-Gonadotropinen_US
dc.subject.otherProgesterone Productionen_US
dc.subject.otherPreovulatory Folliclesen_US
dc.subject.otherPlasminogen-Activatoren_US
dc.subject.otherLuteinizing-Hormoneen_US
dc.subject.otherPerfused Invitroen_US
dc.subject.otherOvulationen_US
dc.subject.otherProstaglandinen_US
dc.subject.otherInhibitoren_US
dc.titleR5020 enhances PGE2 stimulated steroidogenesis in cultured rat granulosa cellsen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.pmid1301631-
dc.identifier.scopus2-s2.0-0027008738-
dc.identifier.isiA1992KP57300004-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dcterms.isPartOfRevista Espanola De Fisiologia-
dcterms.sourceRevista Espanola De Fisiologia[ISSN 0034-9402],v. 48 (3), p. 167-170-
dc.contributor.authorscopusid7004158812-
dc.contributor.authorscopusid57198495832-
dc.contributor.authorscopusid7003526778-
dc.contributor.authorscopusid7003810011-
dc.contributor.authorscopusid8681043500-
dc.contributor.authorscopusid7003806034-
dc.description.lastpage170en_US
dc.identifier.issue3-
dc.description.firstpage167en_US
dc.relation.volume48en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.wosWOS:A1992KP57300004-
dc.contributor.daisngid1127140-
dc.contributor.daisngid16700767-
dc.contributor.daisngid32482890-
dc.contributor.daisngid329218-
dc.contributor.daisngid30844495-
dc.contributor.daisngid384944-
dc.contributor.daisngid128315-
dc.contributor.daisngid1664323-
dc.identifier.investigatorRIDK-5125-2014-
dc.identifier.investigatorRIDK-5709-2014-
dc.description.numberofpages4en_US
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:FANJUL, LF-
dc.contributor.wosstandardWOS:GONZALEZ, J-
dc.contributor.wosstandardWOS:SANTANA, P-
dc.contributor.wosstandardWOS:ESTEVEZ, F-
dc.contributor.wosstandardWOS:QUINTANA, J-
dc.contributor.wosstandardWOS:DEGALARRETA, CMR-
dc.date.coverdateDiciembre 1992en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptDepartamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología-
crisitem.author.deptGIR Estadística-
crisitem.author.deptDepartamento de Matemáticas-
crisitem.author.deptGIR IUIBS: Bioquímica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología-
crisitem.author.orcid0009-0000-1982-055X-
crisitem.author.orcid0000-0003-1681-7165-
crisitem.author.orcid0000-0002-9728-2774-
crisitem.author.parentorgDepartamento de Matemáticas-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameFanjul Rodríguez, Luisa Fernanda-
crisitem.author.fullNameSaavedra Santana, Pedro-
crisitem.author.fullNameEstévez Rosas, Francisco Jesús-
crisitem.author.fullNameRuiz De Galarreta Hernandez,C. Manuel-
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