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Title: Effects of Menadione Sodium Bisulphite (Vitamin K3) Supplementation of the Diets Based on Plant Feed Ingredients on Growth and Bone Health of Gilthead Seabream (Sparus aurata) Fingerlings
Authors: Domínguez Montesdeoca, David 
Castro Alonso, Pedro Luis 
Lall, Santosh
Montero Vítores, Daniel 
Zamorano Serrano, María Jesús 
Fontanillas, Ramon
Izquierdo López, María Soledad 
Editors: Dawood, Mahmoud
UNESCO Clasification: 310502 Piscicultura
310406 Nutrición
Issue Date: 2022
Project: Consumer driven Production: Integrating Innovative Approaches for Competitive and Sustainable Performance across the Mediterranean Aquaculture Value Chain 
Journal: Aquaculture Nutrition 
Abstract: The nutritional profile of aquaculture feeds can be altered with substitution of fish-based ingredients, including the vitamin contents, ultimately affecting the vitamin supply to fish. Requirements for several vitamins have been described for early life stages of species including some as salmonids and carps, but optimum levels for gilthead seabream fingerlings have not been described for most vitamins. In order to evaluate the essentiality of vitamin K in gilthead seabream fingerlings, a basal diet with low levels of marine ingredients (FM 10% and FO 6%) designed to contain five supplementation levels of vitamin K3 (0.1, 2.8, 6.3, 12.0, and 23.0 mg kg-1) was tested for 70 days. Growth and productive parameters were monitored along the trial and samples for X-ray analyses, and bone and liver molecular markers, histology, and proximal composition were taken. At the end of the experiment, growth, grp expression, and the reduced prevalence of skeletal disorders suggested that dietary vitamin K3 levels for gilthead seabream fingerlings should be above 12 mg kg-1 in diets containing a larger proportion of plant protein and vegetable oils.
ISSN: 1365-2095
DOI: 10.1155/2022/1613030
Source: Aquaculture Research [ISSN 1355-557X], v. 2022, 1613030, (2022)
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