Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/112681
Title: High Fruit and Vegetable Consumption and Moderate Fat Intake Are Associated with Higher Carotenoid Concentration in Human Plasma
Authors: Marhuenda-Munoz, M
de Alvarenga, JFR
Hernaez, A
Tresserra-Rimbau, A
Martinez-Gonzalez, MA
Salas-Salvado, J
Corella, D
Malcampo, M
Martinez, JA
Alonso-Gomez, AM
Warnberg, J
Vioque, J
Romaguera, D
Lopez-Miranda, J
Estruch, R
Tinahones, FJ
Lapetra, J
Serra-Majem, Ll 
Bueno-Cavanillas, A
Tur, JA
Sanchez, VM
Pinto, X
Delgado-Rodriguez, M
Matia-Martin, P
Vidal, J
Vázquez. C.
Daimiel, L
Ros, E
Serra-Mir, M
Vazquez-Ruiz, Z
Nishi, SK
Sorli, JV
Zomeno, MD
Zulet, MA
Vaquero-Luna, J
Carabano-Moral, R
Notario-Barandiaran, L
Morey, M
Garcia-Rios, A
Gomez-Perez, AM
Santos-Lozano, JM
Buil-Cosiales, P
Basora, J
Portoles, O
Schroder, H
Abete, I
Salaverria-Lete, I
Toledo, E
Babio, N
Fito, M
Martinez-Huelamo, M
Lamuela-Raventos, RM
UNESCO Clasification: 32 Ciencias médicas
3206 Ciencias de la nutrición
Keywords: Bioactive compounds
Phytochemicals
Dietary fats
Mediterranean diet
PREDIMED-Plus study, et al
Issue Date: 2021
Project: Efecto de Una Pérdida de Peso Con Dieta Mediterránea Hipocalórica y Promoción de la Actividad Física en la Prevención Primaria Cardiovascular 
Efecto de la dieta mediterránea hopocalórica y promoción de la actividad física en prevención primaria cardiovascular.Estudio piloto sobre marcadores intermedios. 
Journal: Antioxidants 
Abstract: Carotenoids are pigments contained mainly in fruit and vegetables (F&V) that have bene-ficial effects on cardiometabolic health. Due to their lipophilic nature, co-ingestion of fat appears to increase their bioavailability via facilitating transfer to the aqueous micellar phase during diges-tion. However, the extent to which high fat intake may contribute to increased carotenoid plasma concentrations is still unclear. The objective was to examine the degree to which the consumption of different amounts of both carotenoid-rich foods and fats is associated with plasma carotenoid concentrations within a Mediterranean lifestyle context (subsample from the PREDIMED-Plus study baseline) where consumption of F&V and fat is high. The study population was catego-rized into four groups according to their self-reported consumption of F&V and fat. Carotenoids were extracted from plasma samples and analyzed by HPLC-UV-VIS-QqQ-MS/MS. Carotenoid systemic concentrations were greater in high consumers of F&V than in low consumers of these foods (+3.04 µmol/L (95% CI: 0.90, 5.17), p-value = 0.005), but circulating concentrations seemed to decrease when total fat intake was very high (−2.69 µmol/L (−5.54; 0.16), p-value = 0.064). High consumption of F&V is associated with greater systemic levels of total carotenoids, in particular when fat intake is low-to-moderate rather than very high.
URI: http://hdl.handle.net/10553/112681
ISSN: 2076-3921
DOI: 10.3390/antiox10030473
Source: Antioxidants [ISSN 2076-3921], v. 10(3), 473
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