Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/112105
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ramos-Vivas, José | en_US |
dc.contributor.author | Superio, Joshua | en_US |
dc.contributor.author | Galindo-Villegas, Jorge | en_US |
dc.contributor.author | Acosta Arbelo, Félix Antonio | en_US |
dc.date.accessioned | 2021-10-05T10:56:37Z | - |
dc.date.available | 2021-10-05T10:56:37Z | - |
dc.date.issued | 2021 | en_US |
dc.identifier.issn | 1422-0067 | en_US |
dc.identifier.uri | http://hdl.handle.net/10553/112105 | - |
dc.description.abstract | Therapeutic bacteriophages, commonly called as phages, are a promising potential alternative to antibiotics in the management of bacterial infections of a wide range of organisms including cultured fish. Their natural immunogenicity often induces the modulation of a variated collection of immune responses within several types of immunocytes while promoting specific mechanisms of bacterial clearance. However, to achieve standardized treatments at the practical level and avoid possible side effects in cultivated fish, several improvements in the understanding of their biology and the associated genomes are required. Interestingly, a particular feature with therapeutic potential among all phages is the production of lytic enzymes. The use of such enzymes against human and livestock pathogens has already provided in vitro and in vivo promissory results. So far, the best-understood phages utilized to fight against either Gram-negative or Gram-positive bacterial species in fish culture are mainly restricted to the Myoviridae and Podoviridae, and the Siphoviridae, respectively. However, the current functional use of phages against bacterial pathogens of cultured fish is still in its infancy. Based on the available data, in this review, we summarize the current knowledge about phage, identify gaps, and provide insights into the possible bacterial control strategies they might represent for managing aquaculture-related bacterial diseases. | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | International Journal of Molecular Sciences | en_US |
dc.source | International Journal of Molecular Sciences [ISSN 1422-0067], v. 22(19), 10436 | en_US |
dc.subject | 310502 Piscicultura | en_US |
dc.subject | 310907 Patología | en_US |
dc.subject | 310903 Inmunología | en_US |
dc.subject.other | Aquaculture | en_US |
dc.subject.other | Bacteriophages | en_US |
dc.subject.other | Disease management | en_US |
dc.subject.other | Fish | en_US |
dc.subject.other | Immunology | en_US |
dc.subject.other | Lytic enzymes | en_US |
dc.subject.other | Pathogens | en_US |
dc.title | Phage Therapy as a Focused Management Strategy in Aquaculture | en_US |
dc.type | info:eu-repo/semantics/Article | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.3390/ijms221910436 | en_US |
dc.identifier.issue | 19 | - |
dc.investigacion | Ciencias de la Salud | en_US |
dc.type2 | Artículo | en_US |
dc.utils.revision | Sí | en_US |
dc.identifier.ulpgc | Sí | en_US |
dc.contributor.buulpgc | BU-VET | en_US |
dc.description.sjr | 1,176 | |
dc.description.jcr | 6,208 | |
dc.description.sjrq | Q1 | |
dc.description.jcrq | Q1 | |
dc.description.scie | SCIE | |
dc.description.miaricds | 10,8 | |
item.fulltext | Con texto completo | - |
item.grantfulltext | open | - |
crisitem.author.dept | GIR Grupo de Investigación en Acuicultura | - |
crisitem.author.dept | IU de Investigación en Acuicultura Sostenible y Ec | - |
crisitem.author.dept | Departamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos | - |
crisitem.author.orcid | 0000-0002-1098-7529 | - |
crisitem.author.parentorg | IU de Investigación en Acuicultura Sostenible y Ec | - |
crisitem.author.fullName | Ramos Vivas, José | - |
crisitem.author.fullName | Acosta Arbelo, Félix Antonio | - |
Appears in Collections: | Artículos |
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