Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/106863
Título: Spanish Pediatric Inflammatory Bowel Disease Diagnostic Delay Registry: SPIDER Study From Sociedad Española de Gastroenterología, Hepatología y Nutrición Pediátrica
Autores/as: Jiménez Treviño, Santiago
Pujol Muncunill, Gemma
Martín-Masot, Rafael
Rodríguez Martínez, Alejandro
Segarra Cantón, Oscar
Peña Quintana, Luis 
Armas Ramos, Honorio
Eizaguirre Arocena, Francisco Javier
Barrio Torres, Josefa
García Burriel, José Ignacio
Ortigosa Castillo, Luis
Donat Aliaga, Ester
Crujeiras Martínez, Vanesa
Barros García, Patricia
Botija Arcos, Gonzalo
Bartolomé Porro, Juan Manuel
Juste Ruiz, Mercedes
Ochoa Sangrador, Carlos
García Casales, Zuriñe
Galicia Poblet, Gonzalo
Oliver Goicolea, Pablo
Lorenzo Garrido, Helena
García Romero, Ruth
La Orden Izquierdo, Enrique
Pérez Solis, David
Navas-López, Víctor Manuel
Díaz Martin, Juan José
Martín de Carpi, Javier
Clasificación UNESCO: 32 Ciencias médicas
320503 Gastroenterología
320110 Pediatría
Palabras clave: Crohn's disease
Children
Diagnostic delay
Inflammatory bowel disease
Time to diagnosis, et al.
Fecha de publicación: 2020
Publicación seriada: Frontiers in Pediatrics 
Resumen: Background and Aims: Diagnostic delay (DD) is especially relevant in children with inflammatory bowel disease, leading to potential complications. We examined the intervals and factors for DD in the pediatric population of Spain. Methods: We conducted a multicentric prospective study, including 149 pediatric inflammatory bowel disease patients, obtaining clinical, anthropometric, and biochemical data. Time to diagnosis (TD) was divided into several intervals to identify those where the DD was longer and find the variables that prolonged those intervals. Missed opportunities for diagnosis (MODs) were also identified. Results: Overall TD was 4.4 months (interquartile range [IQR] 2.6–10.4), being significantly higher in Crohn's disease (CD) than in ulcerative colitis (UC) (6.3 [IQR 3.3–12.3] vs. 3 [IQR 1.6–5.6] months, p = 0.0001). Time from the visit to the first physician until referral to a pediatric gastroenterologist was the main contributor to TD (2.4 months [IQR 1.03–7.17] in CD vs. 0.83 months [IQR 0.30–2.50] in UC, p = 0.0001). One hundred and ten patients (78.3%) visited more than one physician (29.9% to 4 or more), and 16.3% visited the same physician more than six times before being assessed by the pediatric gastroenterologist. The number of MODs was significantly higher in CD than that in UC patients: 4 MODs (IQR 2–7) vs. 2 MODs ([IQR 1–5], p = 0.003). Referral by pediatricians from hospital care allowed earlier IBD diagnosis (odds ratio 3.2 [95% confidence interval 1.1–8.9], p = 0.025). Conclusions: TD and DD were significantly higher in CD than those in UC. IBD patients (especially those with CD) undergo a large number of medical visits until the final diagnosis.
URI: http://hdl.handle.net/10553/106863
ISSN: 2296-2360
DOI: 10.3389/fped.2020.584278
Fuente: Frontiers in Pediatrics [ISSN 2296-2360], n. 8, 584278 (Octubre 2020)
Colección:Artículos
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