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Title: Microcrystalline cellulose as filler in polycaprolactone matrices
Authors: Alemán Domínguez, María Elena 
Ortega, Zaida 
Benítez, Antonio Nizardo 
Monzón, Mario 
Wang, Ling
Tammaddon, Maryam
Liu, Chaoz
UNESCO Clasification: 3312 Tecnología de materiales
3313 Tecnología e ingeniería mecánicas
Issue Date: 2019
Publisher: CRC Press (Taylor and Francis Group) 
Project: Biomaterials and Additive Manufacturing: Osteochondral Scaffold innovation applied to osteoarthritis 
Abstract: Polycaprolactone is a biomaterial widely used for tissue engineering applications. However, its hydrophobicity hinders cell attachment and proliferation on its surface. In this study microcrystalline cellulose has been proposed as a functional filler for polycaprolactone matrices expected to improve these properties. Composite material samples containing 0, 2, 5, 10 and 20% w/w of microcrystalline cellulose have been manufactured by compression molding and evaluated in terms of their mechanical properties, swelling behavior, water contact angle values and sheep mesenchymal cells viability. The results confirm that the presence of the additive is able to increase the swelling ability of the material (the samples containing 20% w/w of additive are able to absorb an amount of water 6 times higher than the value for polycaprolactone ones), the Young’s modulus (from 224±14 MPa for polycaprolactone to 388±30 MPa for the composites containing 20% of microcrystalline cellulose) and the bioaffinity of polycaprolactone based composite materials.
ISBN: 978-0-367-42272-1
Source: Industry 4.0 – Shaping The Future of The Digital World / Paulo Jorge da Silva Bartolo, Fernando Moreira da Silva, Shaden Jaradat, Helena Bartolo
Appears in Collections:Capítulo de libro
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