Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/105962
Title: Clinical presentation of acute Q fever in Spain: seasonal and geographical differences
Authors: Espejo, E.
Gil Díaz, Aída 
Oteo, J. A.
Castillo-Rueda, R.
García-Alvarez, L.
Santana Baez, S.
Bella, F.
UNESCO Clasification: 32 Ciencias médicas
3205 Medicina interna
Keywords: Coxiella burnetii
Geographical differences
Seasonal variation
Zoonosis
Issue Date: 2014
Journal: International Journal of Infectious Diseases 
Abstract: Objectives. The aims of this study were to improve our understanding of the clinical forms of presentation of acute Q fever in Spain and to determine any possible relationships with geographical and seasonal factors. Methods. This was a retrospective study of 183 cases of acute Q fever from three Spanish regions, Catalonia, Canary Islands, and La Rioja. Results. The main clinical form of presentation was hepatitis (49.2%), followed by isolate febrile syndrome (31.7%) and pneumonia (19.1%). The proportion of cases presenting as pneumonia was significantly higher in La Rioja (40.7%) than in Catalonia (18.3%) or the Canary Islands (12.9%) (p = 0.001). In Catalonia and the Canary Islands, most cases (52.1% and 57.6%, respectively) were diagnosed between March and June, whereas in La Rioja, most cases (51.8%) occurred between November and February. Overall, the proportion of cases presenting as pneumonia was significantly higher in the period from November to February (32.6%) than in the periods March–June (16.0%) and July–October (13.0%) (p = 0.01). Conclusions. Our results suggest the existence of seasonal differences in the presentation of acute Q fever in Spain, with a higher proportion of pneumonic forms in the colder months. Furthermore, we confirmed the existence of geographical differences, with a higher proportion of pneumonic forms in the region of La Rioja, in the north of the country.
URI: http://hdl.handle.net/10553/105962
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2014.06.016
Source: International Journal of Infectious Diseases [ISSN 1201-9712], v. 26, p.162-164 (Septiembre 2014)
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