Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/45982
Title: | Dose-related hemodynamic and renal effects of dopamine in septic shock | Authors: | de La Cal, M. A. Miravalles, E. Pascual, T. Esteban, A. Ruiz-Santana, S. |
UNESCO Clasification: | 32 Ciencias médicas 3205 Medicina interna |
Keywords: | Dopamine Septic shock |
Issue Date: | 1984 | Journal: | Critical Care Medicine | Abstract: | We studied hemodynamic and renal effects of increasing the dosage of dopamine (DP) by 5 micrograms/kg X min, in 7 patients with peritonitis and clinical findings of septic shock, all of whom were already receiving variable dosages of DP. Stroke index (SI) (p less than .01), except in 3 cases, and mean arterial pressure (p less than .01) were significantly elevated without significant increases in HR and systemic vascular resistance index (SVRI). Changes in mean pulmonary artery pressure (MPAP) and pulmonary wedge pressure (WP) were insignificant (less than 3 mm Hg). Renal response showed augmentation of diuresis (p less than .01), inulin clearance (Cin) (p less than .05), and fractional excretion of sodium (FENa) (p = .02) without significant changes in either paraminohypurate clearance (Cpha) or filtration fraction. There was no correlation between hemodynamic or renal changes and initial dosage of DP. We conclude that increasing the DP dosage in septic shock patients may be useful even when the patient is already receiving large doses. Increased natriuresis was not due to changes in plasma renal flow. | URI: | http://hdl.handle.net/10553/45982 | ISSN: | 0090-3493 | DOI: | 10.1097/00003246-198401000-00006 | Source: | Critical Care Medicine [ISSN 0090-3493],v. 12, p. 22-25 |
Appears in Collections: | Artículos |
SCOPUSTM
Citations
23
checked on May 12, 2024
Page view(s)
53
checked on Dec 16, 2023
Google ScholarTM
Check
Altmetric
Share
Export metadata
Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.