Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/77716
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dc.contributor.authorGroch, K. R.en_US
dc.contributor.authorDiaz Delgado, Josueen_US
dc.contributor.authorSantos-Neto, E. B.en_US
dc.contributor.authorIkeda, J. M. P.en_US
dc.contributor.authorCarvalho, R. R.en_US
dc.contributor.authorOliveira, R. B.en_US
dc.contributor.authorGuari, E. B.en_US
dc.contributor.authorFlach, L.en_US
dc.contributor.authorSierra Pulpillo, Eva Maríaen_US
dc.contributor.authorAlves Godinho,Anaen_US
dc.contributor.authorFernández Rodríguez, Antonio Jesúsen_US
dc.contributor.authorKeid, L. B.en_US
dc.contributor.authorSoares, R. M.en_US
dc.contributor.authorKanamura, C. T.en_US
dc.contributor.authorFavero, C.en_US
dc.date.accessioned2021-02-12T11:21:03Z-
dc.date.available2021-02-12T11:21:03Z-
dc.date.issued2020en_US
dc.identifier.issn1544-2217en_US
dc.identifier.urihttp://hdl.handle.net/10553/77716-
dc.description.abstractCetacean morbillivirus (CeMV; Paramyxoviridae) is the most significant pathogen of cetaceans worldwide. The novel “multi-host” Guiana dolphin (Sotalia guianensis; GD)-CeMV strain is reported in South American waters and infects Guiana dolphins and southern right whales (Eubalaena australis). This study aimed to describe the pathologic findings, GD-CeMV viral antigen distribution and detection by RT-PCR (reverse transcriptase polymerase chain reaction), and infectious comorbidities in 29 Guiana dolphins that succumbed during an unusual mass-mortality event in Rio de Janeiro state, Brazil, between November 2017 and March 2018. The main gross findings were lack of ingesta, pulmonary edema, ascites, icterus, hepatic lipidosis, multicentric lymphadenomegaly, as well as pneumonia, polyserositis, and multiorgan vasculitis caused by Halocercus brasiliensis. Microscopically, the primary lesions were bronchointerstitial pneumonia and multicentric lymphoid depletion. The severity and extent of the lesions paralleled the distribution and intensity of morbilliviral antigen. For the first time in cetaceans, morbilliviral antigen was detected in salivary gland, optic nerve, heart, diaphragm, parietal and visceral epithelium of glomeruli, vulva, and thyroid gland. Viral antigen within circulating leukocytes suggested this as a mechanism of dissemination within the host. Comorbidities included disseminated toxoplasmosis, mycosis, ciliated protozoosis, and bacterial disease including brucellosis. These results provide strong evidence for GD-CeMV as the main cause of this unusual mass-mortality event.en_US
dc.languagespaen_US
dc.relation.ispartofVeterinary Pathologyen_US
dc.sourceVeterinary Pathology [E1544-2217], v. 57 (6), p. 845-857en_US
dc.subject3105 Peces y fauna silvestreen_US
dc.subject240119 Zoología marinaen_US
dc.subject310907 Patologíaen_US
dc.subject.otherGuiana dolphinen_US
dc.subject.otherParamyxoviridaeen_US
dc.subject.otherSotalia guianensien_US
dc.subject.otherToxoplasma gondiien_US
dc.subject.otherCetacean morbillivirusen_US
dc.subject.otherCiliated protozoaen_US
dc.subject.otherMarine mammal pathologyen_US
dc.subject.otherMycosisen_US
dc.titleThe Pathology of Cetacean Morbillivirus Infection and Comorbidities in Guiana Dolphins During an Unusual Mortality Event (Brazil, 2017-2018)en_US
dc.typeArticleen_US
dc.identifier.doi10.1177/0300985820954550en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.utils.revisionen_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-VETen_US
dc.description.sjr0,794
dc.description.jcr2,221
dc.description.sjrqQ1
dc.description.jcrqQ2
dc.description.scieSCIE
item.grantfulltextopen-
item.fulltextCon texto completo-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.deptGIR Histología y Patología Veterinaria-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.orcid0000-0003-1216-5446-
crisitem.author.orcid0000-0003-3749-8845-
crisitem.author.orcid0000-0001-5281-0521-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.fullNameDiaz Delgado, Josue-
crisitem.author.fullNameSierra Pulpillo, Eva María-
crisitem.author.fullNameAlves Godinho,Ana-
crisitem.author.fullNameFernández Rodríguez, Antonio Jesús-
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