Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/73501
DC FieldValueLanguage
dc.contributor.authorAlmirante, Benitoen_US
dc.contributor.authorGarnacho-Montero, Joseen_US
dc.contributor.authorMaseda, Emilioen_US
dc.contributor.authorJavier Candel, Franciscoen_US
dc.contributor.authorGrau, Santiagoen_US
dc.contributor.authorGuinea, Jesusen_US
dc.contributor.authorMoreno, Ignacioen_US
dc.contributor.authorMunoz, Patriciaen_US
dc.contributor.authorRuiz Santana, Sergioen_US
dc.date.accessioned2020-06-26T11:52:36Z-
dc.date.available2020-06-26T11:52:36Z-
dc.date.issued2017en_US
dc.identifier.issn0214-3429en_US
dc.identifier.otherWoS-
dc.identifier.urihttp://hdl.handle.net/10553/73501-
dc.description.abstractIntroduction. Invasive infections caused by Candida spp. in critically ill patients may significantly worsen their prognosis, so it is of great importance to establish an early detection and a suitable therapeutic strategy. The objective of this study was to define the differential role of echinocandins in treating certain critical patient profiles.Methodology. A scientific committee of 9 experts in infectious diseases, critical care, microbiology, and hospital pharmacy reviewed the existing evidence on the treatment of candidemia and invasive candidiasis in critically ill patients. After that, a questionnaire with 35 items was elaborated to be agreed by 26 specialists in the aforementioned disciplines using a modified Delphi method.Results. After two rounds of evaluation, a consensus was reached in terms of agreement in 66% of the items. Some of the consensuses achieved included: it is not necessary to adjust the dose of echinocandins during renal replacement therapy; the echinocandins are the empirical and/or directed treatment of choice for candidemia and invasive candidiasis associated with biofilms; these drugs may be used in the antifungal prophylaxis of high-risk liver transplantation. In the absence of additional clinical data, it should be noted that micafungin is the echinocandin with the most available scientific evidence.Conclusions. The experts consulted showed a high degree of agreement on some of the most controversial aspects regarding the management of candidemia and invasive candidiasis in critical patients, which could inform of practical recommendations for their treatment.en_US
dc.languageengen_US
dc.relation.ispartofRevista Espanola de Quimioterapiaen_US
dc.sourceRevista Espanola De Quimioterapia [ISSN 0214-3429], v. 30 (5), p. 355-367, (Octubre 2017)en_US
dc.subject320806 Quimioterapiaen_US
dc.subject.otherContinuous Venovenous Hemofiltrationen_US
dc.subject.otherLiver-Transplant Recipientsen_US
dc.subject.otherSevere Abdominal Conditionsen_US
dc.subject.otherEscmid-Asterisk Guidelineen_US
dc.subject.otherRenal Replacement Therapyen_US
dc.subject.otherIntensive-Care-Uniten_US
dc.subject.otherIcu Patientsen_US
dc.subject.otherPopulation Pharmacokineticsen_US
dc.subject.otherFungal-Infectionen_US
dc.subject.otherAdult Patientsen_US
dc.subject.otherCritical Patientsen_US
dc.subject.otherCandidemiaen_US
dc.subject.otherInvasive Candidiasisen_US
dc.subject.otherAntifungal Therapyen_US
dc.subject.otherEchinocandinsen_US
dc.titleCandidemia and invasive candidiasis approach in critically ill patients: role of the echinocandinsen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.scopus85038351142-
dc.identifier.isi000419125200008-
dc.contributor.authorscopusid7006275453-
dc.contributor.authorscopusid56266246000-
dc.contributor.authorscopusid6603190773-
dc.contributor.authorscopusid36773368900-
dc.contributor.authorscopusid7003696949-
dc.contributor.authorscopusid7005645840-
dc.contributor.authorscopusid57203079724-
dc.contributor.authorscopusid56204741800-
dc.contributor.authorscopusid55518542700-
dc.identifier.eissn1988-9518-
dc.description.lastpage367en_US
dc.identifier.issue5-
dc.description.firstpage355en_US
dc.relation.volume30en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.contributor.daisngid109387-
dc.contributor.daisngid248895-
dc.contributor.daisngid667921-
dc.contributor.daisngid29953915-
dc.contributor.daisngid153796-
dc.contributor.daisngid103917-
dc.contributor.daisngid1981988-
dc.contributor.daisngid7999-
dc.contributor.daisngid839958-
dc.description.numberofpages13en_US
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Almirante, B-
dc.contributor.wosstandardWOS:Garnacho-Montero, J-
dc.contributor.wosstandardWOS:Maseda, E-
dc.contributor.wosstandardWOS:Candel, FJ-
dc.contributor.wosstandardWOS:Grau, S-
dc.contributor.wosstandardWOS:Guinea, J-
dc.contributor.wosstandardWOS:Moreno, I-
dc.contributor.wosstandardWOS:Munoz, P-
dc.contributor.wosstandardWOS:Ruiz-Santana, S-
dc.date.coverdateEnero 2017en_US
dc.identifier.ulpgces
dc.description.sjr0,254
dc.description.jcr0,605
dc.description.sjrqQ3
dc.description.jcrqQ4
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGrupo de investigaciones infecciosas, nutricionales e inflamatorias en pacientes hospitalarios / Study Group on infectious, nutritional and inflammatory diseases in hospitalized patients-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0003-3927-3236-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameRuiz Santana, Sergio-
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