Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/73429
DC Field | Value | Language |
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dc.contributor.author | Pérez López, Laura Del Carmen | en_US |
dc.contributor.author | Boronat Cortés, Mauro | en_US |
dc.contributor.author | Melián Limiñana, Carlos | en_US |
dc.contributor.author | Brito Casillas, Yeray | en_US |
dc.contributor.author | Wägner, Anna Maria Claudia | en_US |
dc.date.accessioned | 2020-06-22T11:42:14Z | - |
dc.date.available | 2020-06-22T11:42:14Z | - |
dc.date.issued | 2020 | en_US |
dc.identifier.issn | 0165-2176 | en_US |
dc.identifier.other | Scopus | - |
dc.identifier.uri | http://hdl.handle.net/10553/73429 | - |
dc.description.abstract | Background: In people, obesity and prediabetes mellitus might predispose to chronic kidney disease (CKD). Aims: To assess the association of overweight [Body condition score (BCS) >5] and glucose metabolism alterations, with established or potential markers of CKD. In addition, fructosamine and fasted blood glucose were compared as predictors of early abnormal glucose metabolism. Methods: 54 clinically healthy cats were included in a cross-sectional study comprising 25 neutered males and 29 (28 neutered) females aged 7.2 (5.5–9.4) years. Two potential markers of CKD, namely urinary free active transforming growth factor-β1-creatinine ratio and urinary retinol binding protein-creatinine ratio were measured along with other parameters to assess CKD. A receiver operating curve was used to identify the best sensitivity and specificity of fructosamine to identify cats with fasting glucose >6.5 mmol/L. Results: No association was found between BCS and markers of CKD. Fructosamine was greater in cats with fasting glucose >6.5 mmol/L compared to those with fasting glucose ≤6.5 mmol/L. A fructosamine concentration ≥250 µmol/L was able to detect cats with hyperglycemia with a sensitivity of 77% and a specificity of 65%. Furthermore, fructosamine was more strongly correlated with fasting glucose than albumin-corrected fructosamine (r = 0.43, p = 0.002 vs r = 0.32, p = 0.026). Cats with higher fructosamine had lower serum symmetric dimethylarginine concentrations. Conclusion: The present study does not suggest an effect of obesity on renal function in domestic cats. Clinical relevance: Fructosamine might be of value for the diagnosis of prediabetes mellitus in cats. | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | Veterinary Quarterly | en_US |
dc.source | Veterinary Quarterly [ISSN 0165-2176], v. 40 (1), p. 132-139, (Enero 2020) | en_US |
dc.subject | 310907 Patología | en_US |
dc.subject.other | Active Transforming Growth Factor-Β1 | en_US |
dc.subject.other | Cat | en_US |
dc.subject.other | Diabetes Mellitus | en_US |
dc.subject.other | Feline | en_US |
dc.subject.other | Fructosamine | en_US |
dc.subject.other | Metabolic Syndrome | en_US |
dc.subject.other | Nephropathy | en_US |
dc.subject.other | Obesity | en_US |
dc.subject.other | Retinol Biding Protein | en_US |
dc.subject.other | Symmetric Dimethyl Arginine | en_US |
dc.title | Kidney function and glucose metabolism in overweight and obese cats | en_US |
dc.type | info:eu-repo/semantics/Article | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1080/01652176.2020.1759844 | en_US |
dc.identifier.scopus | 85084489537 | - |
dc.contributor.authorscopusid | 57210211437 | - |
dc.contributor.authorscopusid | 7003952293 | - |
dc.contributor.authorscopusid | 55220360000 | - |
dc.contributor.authorscopusid | 56236021400 | - |
dc.contributor.authorscopusid | 7401456520 | - |
dc.identifier.eissn | 1875-5941 | - |
dc.description.lastpage | 139 | en_US |
dc.identifier.issue | 1 | - |
dc.description.firstpage | 132 | en_US |
dc.relation.volume | 40 | en_US |
dc.investigacion | Ciencias de la Salud | en_US |
dc.type2 | Artículo | en_US |
dc.utils.revision | Sí | en_US |
dc.date.coverdate | Enero 2020 | en_US |
dc.identifier.ulpgc | Sí | en_US |
dc.contributor.buulpgc | BU-MED | en_US |
dc.description.sjr | 0,937 | |
dc.description.jcr | 3,32 | |
dc.description.sjrq | Q1 | |
dc.description.jcrq | Q1 | |
dc.description.scie | SCIE | |
item.grantfulltext | none | - |
item.fulltext | Sin texto completo | - |
crisitem.author.dept | GIR IUIBS: Diabetes y endocrinología aplicada | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | GIR IUIBS: Diabetes y endocrinología aplicada | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Ciencias Médicas y Quirúrgicas | - |
crisitem.author.dept | GIR IUIBS: Diabetes y endocrinología aplicada | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos | - |
crisitem.author.dept | GIR IUIBS: Diabetes y endocrinología aplicada | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | GIR IUIBS: Diabetes y endocrinología aplicada | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Ciencias Médicas y Quirúrgicas | - |
crisitem.author.orcid | 0000-0003-0541-3675 | - |
crisitem.author.orcid | 0000-0001-8535-8543 | - |
crisitem.author.orcid | 0000-0002-1496-5706 | - |
crisitem.author.orcid | 0000-0002-0707-7444 | - |
crisitem.author.orcid | 0000-0002-7663-9308 | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.fullName | Pérez López, Laura Del Carmen | - |
crisitem.author.fullName | Boronat Cortés, Mauro | - |
crisitem.author.fullName | Melián Limiñana, Carlos | - |
crisitem.author.fullName | Brito Casillas, Yeray | - |
crisitem.author.fullName | Wägner, Anna Maria Claudia | - |
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