Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/73429
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dc.contributor.authorPérez López, Laura Del Carmenen_US
dc.contributor.authorBoronat Cortés, Mauroen_US
dc.contributor.authorMelián Limiñana, Carlosen_US
dc.contributor.authorBrito Casillas, Yerayen_US
dc.contributor.authorWägner, Anna Maria Claudiaen_US
dc.date.accessioned2020-06-22T11:42:14Z-
dc.date.available2020-06-22T11:42:14Z-
dc.date.issued2020en_US
dc.identifier.issn0165-2176en_US
dc.identifier.otherScopus-
dc.identifier.urihttp://hdl.handle.net/10553/73429-
dc.description.abstractBackground: In people, obesity and prediabetes mellitus might predispose to chronic kidney disease (CKD). Aims: To assess the association of overweight [Body condition score (BCS) >5] and glucose metabolism alterations, with established or potential markers of CKD. In addition, fructosamine and fasted blood glucose were compared as predictors of early abnormal glucose metabolism. Methods: 54 clinically healthy cats were included in a cross-sectional study comprising 25 neutered males and 29 (28 neutered) females aged 7.2 (5.5–9.4) years. Two potential markers of CKD, namely urinary free active transforming growth factor-β1-creatinine ratio and urinary retinol binding protein-creatinine ratio were measured along with other parameters to assess CKD. A receiver operating curve was used to identify the best sensitivity and specificity of fructosamine to identify cats with fasting glucose >6.5 mmol/L. Results: No association was found between BCS and markers of CKD. Fructosamine was greater in cats with fasting glucose >6.5 mmol/L compared to those with fasting glucose ≤6.5 mmol/L. A fructosamine concentration ≥250 µmol/L was able to detect cats with hyperglycemia with a sensitivity of 77% and a specificity of 65%. Furthermore, fructosamine was more strongly correlated with fasting glucose than albumin-corrected fructosamine (r = 0.43, p = 0.002 vs r = 0.32, p = 0.026). Cats with higher fructosamine had lower serum symmetric dimethylarginine concentrations. Conclusion: The present study does not suggest an effect of obesity on renal function in domestic cats. Clinical relevance: Fructosamine might be of value for the diagnosis of prediabetes mellitus in cats.en_US
dc.languageengen_US
dc.relation.ispartofVeterinary Quarterlyen_US
dc.sourceVeterinary Quarterly [ISSN 0165-2176], v. 40 (1), p. 132-139, (Enero 2020)en_US
dc.subject310907 Patologíaen_US
dc.subject.otherActive Transforming Growth Factor-Β1en_US
dc.subject.otherCaten_US
dc.subject.otherDiabetes Mellitusen_US
dc.subject.otherFelineen_US
dc.subject.otherFructosamineen_US
dc.subject.otherMetabolic Syndromeen_US
dc.subject.otherNephropathyen_US
dc.subject.otherObesityen_US
dc.subject.otherRetinol Biding Proteinen_US
dc.subject.otherSymmetric Dimethyl Arginineen_US
dc.titleKidney function and glucose metabolism in overweight and obese catsen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1080/01652176.2020.1759844en_US
dc.identifier.scopus85084489537-
dc.contributor.authorscopusid57210211437-
dc.contributor.authorscopusid7003952293-
dc.contributor.authorscopusid55220360000-
dc.contributor.authorscopusid56236021400-
dc.contributor.authorscopusid7401456520-
dc.identifier.eissn1875-5941-
dc.description.lastpage139en_US
dc.identifier.issue1-
dc.description.firstpage132en_US
dc.relation.volume40en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.utils.revisionen_US
dc.date.coverdateEnero 2020en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr0,937
dc.description.jcr3,32
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR IUIBS: Diabetes y endocrinología aplicada-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptGIR IUIBS: Diabetes y endocrinología aplicada-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.deptGIR IUIBS: Diabetes y endocrinología aplicada-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.deptGIR IUIBS: Diabetes y endocrinología aplicada-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptGIR IUIBS: Diabetes y endocrinología aplicada-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0003-0541-3675-
crisitem.author.orcid0000-0001-8535-8543-
crisitem.author.orcid0000-0002-1496-5706-
crisitem.author.orcid0000-0002-0707-7444-
crisitem.author.orcid0000-0002-7663-9308-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNamePérez López,Laura Del Carmen-
crisitem.author.fullNameBoronat Cortés, Mauro-
crisitem.author.fullNameMelián Limiñana, Carlos-
crisitem.author.fullNameBrito Casillas, Yeray-
crisitem.author.fullNameWägner, Anna Maria Claudia-
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