Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/71332
Título: Metastatic pulmonary carcinoma in a long-finned pilot whale (Globicephala melas)
Autores/as: Suarez Santana, Cristian Manuel 
Fernández Maldonado, Carolina
Díaz-Delgado, Josué 
Arbelo Hernández, Manuel Antonio 
Suárez-Bonnet, A. 
Espinosa de los Monteros y Zayas, Antonio 
Sierra Pulpillo, Eva María 
Fernández Rodríguez, Antonio Jesús 
Clasificación UNESCO: 310907 Patología
3109 Ciencias veterinarias
Fecha de publicación: 2016
Resumen: We describe gross, histopathological and immunohistochemical features of a pulmonary carcinoma with disseminated metastases in a long-finned pilot whale (LFPW). An adult, female LFPW stranded alive in the south cost of Spain (36°05'49.5"N, -5°26'33.0"W; Algeciras, Andalucía) in 2011. The animal died shortly after. On necropsy examination multiple pulmonary nodules and generalized thoracic lymphadenomegaly were noted. Histologically, the pulmonary parenchyma, mediastinal and pulmonary associated lymph nodes, and the right adrenal gland cortex were invaded by a multifocally coalescing, poorly demarcated, unencapsulated, moderately cellular and highly infiltrative neoplasm. It was composed of disorganized acini, tubules and variably sized and dilated intercommunicating glands lined by neoplastic epithelial cells. Immunohistochemically neoplastic cells were AE1/AE3and vimentin positive. Vasculogenic mimicry and epithelial immunophenotype suggestive of mesenchymal transition were also noticed. Based on above findings a metastatic pulmonary carcinoma was determined. Primary pulmonary neoplasia has been rarely identified in cetaceans with only two descriptions of primary pulmonary squamous cell carcinoma (SCC) in an Amazon River dolphin (Inia geoffrensis) and in a bottlenose dolphin (Tursiops truncatus), hemangiomas in bottlenose dolphin, common dolphin (Delphinus delphis) and beluga whales (Delphinapterus leucas), fibromas in blue whale (Balaenoptera musculus) and fin whale (Balaenoptera physalus), and a chondroma and lipoma in a beluga whale. This is the first report of a pulmonary carcinoma in a LFPW.
URI: http://hdl.handle.net/10553/71332
Fuente: 30th Annual Conference of the European Cetacean Society. Madeira, Portugal, 14-16 March 2016 / Luís Freitas; Cláudia Ribeiro (ed.), p. 215
Colección:Actas de congresos
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