Identificador persistente para citar o vincular este elemento:
http://hdl.handle.net/10553/71004
Campo DC | Valor | idioma |
---|---|---|
dc.contributor.author | Calbet, José A. | en_US |
dc.contributor.author | Martín Rodríguez, Saúl | en_US |
dc.contributor.author | Martín Rincón, Marcos | en_US |
dc.contributor.author | Morales Álamo, David | en_US |
dc.date.accessioned | 2020-03-21T06:06:01Z | - |
dc.date.accessioned | 2020-04-24T15:11:08Z | - |
dc.date.available | 2020-03-21T06:06:01Z | - |
dc.date.available | 2020-04-24T15:11:08Z | - |
dc.date.issued | 2020 | en_US |
dc.identifier.issn | 2213-2317 | en_US |
dc.identifier.other | Scopus | - |
dc.identifier.other | WoS | - |
dc.identifier.uri | http://hdl.handle.net/10553/71004 | - |
dc.description.abstract | During exercise, muscle ATP demand increases with intensity, and at the highest power output, ATP consumption may increase more than 100-fold above the resting level. The rate of mitochondrial ATP production during exercise depends on the availability of O2, carbon substrates, reducing equivalents, ADP, Pi, free creatine, and Ca2+. It may also be modulated by acidosis, nitric oxide and reactive oxygen and nitrogen species (RONS). During fatiguing and repeated sprint exercise, RONS production may cause oxidative stress and damage to cellular structures and may reduce mitochondrial efficiency. Human studies indicate that the relatively low mitochondrial respiratory rates observed during sprint exercise are not due to lack of O2, or insufficient provision of Ca2+, reduced equivalents or carbon substrates, being a suboptimal stimulation by ADP the most plausible explanation. Recent in vitro studies with isolated skeletal muscle mitochondria, studied in conditions mimicking different exercise intensities, indicate that ROS production during aerobic exercise amounts to 1-2 orders of magnitude lower than previously thought. In this review, we will focus on the mechanisms regulating mitochondrial respiration, particularly during high-intensity exercise. We will analyze the factors that limit mitochondrial respiration and those that determine mitochondrial efficiency during exercise. Lastly, the differences in mitochondrial respiration between men and women will be addressed. | en_US |
dc.language | eng | en_US |
dc.relation | Viabilidad y Sostenibilidad Del Adelgazamiento Mediante Tratamiento Intensificado en Pacientes Con Sobrepeso U Obesidad: Mecanismos Neuroendocrinos y Moleculares | en_US |
dc.relation | Identificacion E Integracion de Nuevos Factores Moleculares, Fisiologicos y Bioelectricos Determinantes Del Rendimiento en El Ejercicio de Sprint | en_US |
dc.relation | Desarrollo y Caracterización Molecular de Un Nuevo Modelo de Precondicionamiento Remoto | en_US |
dc.relation | Estudio Longitudinal de Los Efectos de Una Modificación Intensiva Del Estilo de Vida en la Composición Corporal E Indicadores Bioquímicos y Moleculares de Salud en Pacientes Con Sobrepeso y Obesidad: Aplicación Para la Evaluación Fisiológica de Rutas y Sistemas de Monitorización Del Esfuerzo | en_US |
dc.relation.ispartof | Redox Biology | en_US |
dc.source | Redox Biology [ISSN 2213-2317], v. 35, 101478, (Agosto 2020) | en_US |
dc.subject | 2411 Fisiología humana | en_US |
dc.subject | 241106 Fisiología del ejercicio | en_US |
dc.subject.other | Fatigue | en_US |
dc.subject.other | High-Intensity Exercise | en_US |
dc.subject.other | Mitochondrial Respiration | en_US |
dc.subject.other | Oxidative Stress | en_US |
dc.subject.other | Sprint Performance | en_US |
dc.title | An integrative approach to the regulation of mitochondrial respiration during exercise: Focus on high-intensity exercise | en_US |
dc.type | info:eu-repo/semantics/article | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1016/j.redox.2020.101478 | en_US |
dc.identifier.scopus | 85081271807 | - |
dc.identifier.isi | 000542035900014 | - |
dc.contributor.authorscopusid | 7004323423 | - |
dc.contributor.authorscopusid | 56335855800 | - |
dc.contributor.authorscopusid | 56841673800 | - |
dc.contributor.authorscopusid | 35148038500 | - |
dc.relation.volume | 35 | en_US |
dc.investigacion | Ciencias de la Salud | en_US |
dc.type2 | Artículo | en_US |
dc.contributor.daisngid | 30470612 | - |
dc.contributor.daisngid | 40100983 | - |
dc.contributor.daisngid | 31994237 | - |
dc.contributor.daisngid | 32399023 | - |
dc.description.numberofpages | 10 | en_US |
dc.utils.revision | Sí | en_US |
dc.contributor.wosstandard | WOS:Calbet, JAL | - |
dc.contributor.wosstandard | WOS:Martin-Rodriguez, S | - |
dc.contributor.wosstandard | WOS:Martin-Rincon, M | - |
dc.contributor.wosstandard | WOS:Morales-Alamo, D | - |
dc.date.coverdate | Agosto 2020 | en_US |
dc.identifier.ulpgc | Sí | en_US |
dc.contributor.buulpgc | BU-FIS | en_US |
dc.description.sjr | 2,059 | |
dc.description.jcr | 11,799 | |
dc.description.sjrq | Q1 | |
dc.description.jcrq | Q1 | |
dc.description.scie | SCIE | |
item.fulltext | Con texto completo | - |
item.grantfulltext | open | - |
crisitem.project.principalinvestigator | López Calbet, José Antonio | - |
crisitem.project.principalinvestigator | López Calbet, José Antonio | - |
crisitem.project.principalinvestigator | Dorado García, Cecilia | - |
crisitem.project.principalinvestigator | López Calbet, José Antonio | - |
crisitem.author.dept | GIR IUIBS: Rendimiento humano, ejercicio físico y salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Educación Física | - |
crisitem.author.dept | GIR IUIBS: Rendimiento humano, ejercicio físico y salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | GIR IUIBS: Rendimiento humano, ejercicio físico y salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Educación Física | - |
crisitem.author.dept | GIR IUIBS: Rendimiento humano, ejercicio físico y salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Educación Física | - |
crisitem.author.orcid | 0000-0002-9215-6234 | - |
crisitem.author.orcid | 0000-0003-2423-5309 | - |
crisitem.author.orcid | 0000-0002-3685-2331 | - |
crisitem.author.orcid | 0000-0001-8463-397X | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.fullName | López Calbet, José Antonio | - |
crisitem.author.fullName | Martín Rodríguez, Saúl | - |
crisitem.author.fullName | Martín Rincón, Marcos | - |
crisitem.author.fullName | Morales Álamo, David | - |
Colección: | Artículos |
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