Identificador persistente para citar o vincular este elemento:
http://hdl.handle.net/10553/70973
Campo DC | Valor | idioma |
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dc.contributor.author | Sanchez Quiroga, Mª Ángeles | en_US |
dc.contributor.author | Masa Jiménez, Juan Fernando | en_US |
dc.contributor.author | Mokhlesi, Babak | en_US |
dc.contributor.author | Benitez, Ivan | en_US |
dc.contributor.author | Gómez De Terreros, Francisco Javier | en_US |
dc.contributor.author | Romero, Auxiliadora | en_US |
dc.contributor.author | Caballero Eraso, Candela | en_US |
dc.contributor.author | Teran Santos, Joaquin | en_US |
dc.contributor.author | Alonso Álvarez, María Luz | en_US |
dc.contributor.author | Troncoso, Maria Fernanda | en_US |
dc.contributor.author | González, Monica | en_US |
dc.contributor.author | López Martin, Soledad | en_US |
dc.contributor.author | Marín, José María | en_US |
dc.contributor.author | Marti, Sergi | en_US |
dc.contributor.author | Díaz Cambriles, Trinidad | en_US |
dc.contributor.author | Chiner, Eusebi | en_US |
dc.contributor.author | Egea Santaolalla, Carlos | en_US |
dc.contributor.author | Barca, Javier | en_US |
dc.contributor.author | Vázquez Polo, Francisco José | en_US |
dc.contributor.author | Negrín Hernández, Miguel Ángel | en_US |
dc.contributor.author | Martel Escobar, María Carmen | en_US |
dc.contributor.author | Barbe, Ferran | en_US |
dc.contributor.author | Corral, Jaime | en_US |
dc.date.accessioned | 2020-03-18T19:22:16Z | - |
dc.date.available | 2020-03-18T19:22:16Z | - |
dc.date.issued | 2019 | en_US |
dc.identifier.issn | 0903-1936 | en_US |
dc.identifier.uri | http://hdl.handle.net/10553/70973 | - |
dc.description.abstract | Rationale: Obesity hypoventilation syndrome (OHS) is commonly treated with noninvasive ventilation (NIV) or CPAP. NIV is more complex and costly but provides ventilatory support. To date there have been no long-term or cost trials comparing these treatment modalities. Methods: We performed a large, randomized, multicenter, open-label controlled trial in Spain to compare the long-term effectiveness of NIV and CPAP using hospitalization days/year-patient as the primary end point. We carried out a simple cost analysis including effectiveness cost during 3 year of follow-up. We included the following cost groups: visits, adjustment of NIV, tests, medication, therapies and hospital resources utilization. A sensitivity analysis was conducted according to 3 different scenarios guided by the International Gross Domestic Product. Results: In total, 215 patients with untreated OHS and severe obstructive sleep apnea (OSA) were randomized to NIV or CPAP therapy and followed at least 3 years. The effectiveness was close between arms (mean difference NIV-CPAP: -0.19, 95% CI -1.13 to 0.75). The cost per patient/year was lower in the CPAP arm (1,898.2€; SD 1939.5) than the cost in the NIV arm (2,809.3€; SD 2901.6), mean difference -911.1€ (p <0.0001). The sensitivity analysis showed a minimum mean savings per patient/year with CPAP of -553.4€ (p <0.0001) and a maximum of -1,619.5€ (p<0.0001). Conclusions: In stable patients with OHS and severe OSA, despite NIV having a slight advantage in effectiveness, CPAP could be considered the first line of treatment due to its lower cost but, a case-by-case assessment is recommended to detect patients who would benefit from a switch to NIV. | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | European Respiratory Journal | en_US |
dc.source | European Respiratory Journal [ISSN 0903-1936], v. 54 (63), PA2013 | en_US |
dc.subject | 320508 Enfermedades pulmonares | en_US |
dc.subject.other | Apnoea | en_US |
dc.subject.other | Treatments | en_US |
dc.subject.other | RCT (Randomized Controlled Trial) | en_US |
dc.subject.other | Hypopnea | en_US |
dc.title | Long-term positive airway pressure therapy in obesity hypoventilation syndrome. Cost study | en_US |
dc.type | info:eu-repo/semantics/article | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1183/13993003.congress-2019.PA2013 | en_US |
dc.description.firstpage | PA2013 | - |
dc.investigacion | Ciencias de la Salud | en_US |
dc.type2 | Artículo | en_US |
dc.description.notas | ERS International Congress 2019 abstracts. | en_US |
dc.utils.revision | Sí | en_US |
dc.identifier.ulpgc | Sí | es |
dc.description.sjr | 3,398 | |
dc.description.jcr | 12,339 | |
dc.description.sjrq | Q1 | |
dc.description.jcrq | Q1 | |
dc.description.scie | SCIE | |
item.fulltext | Sin texto completo | - |
item.grantfulltext | none | - |
crisitem.author.dept | GIR TIDES- Técnicas estadísticas bayesianas y de decisión en la economía y empresa | - |
crisitem.author.dept | IU de Turismo y Desarrollo Económico Sostenible | - |
crisitem.author.dept | Departamento de Métodos Cuantitativos en Economía y Gestión | - |
crisitem.author.dept | GIR TIDES- Técnicas estadísticas bayesianas y de decisión en la economía y empresa | - |
crisitem.author.dept | IU de Turismo y Desarrollo Económico Sostenible | - |
crisitem.author.dept | Departamento de Métodos Cuantitativos en Economía y Gestión | - |
crisitem.author.dept | GIR TIDES- Técnicas estadísticas bayesianas y de decisión en la economía y empresa | - |
crisitem.author.dept | IU de Turismo y Desarrollo Económico Sostenible | - |
crisitem.author.dept | Departamento de Métodos Cuantitativos en Economía y Gestión | - |
crisitem.author.orcid | 0000-0002-0632-6138 | - |
crisitem.author.orcid | 0000-0002-7074-6268 | - |
crisitem.author.orcid | 0000-0002-7013-4747 | - |
crisitem.author.parentorg | IU de Turismo y Desarrollo Económico Sostenible | - |
crisitem.author.parentorg | IU de Turismo y Desarrollo Económico Sostenible | - |
crisitem.author.parentorg | IU de Turismo y Desarrollo Económico Sostenible | - |
crisitem.author.fullName | Vázquez Polo, Francisco José | - |
crisitem.author.fullName | Negrín Hernández, Miguel Ángel | - |
crisitem.author.fullName | Martel Escobar, María Carmen | - |
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