Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/70951
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dc.contributor.authorPolverino, E.en_US
dc.contributor.authorTorres, A.en_US
dc.contributor.authorMenendez, R.en_US
dc.contributor.authorCillóniz, C.en_US
dc.contributor.authorValles, JMen_US
dc.contributor.authorCapelastegui, Aen_US
dc.contributor.authorMarcos, MAen_US
dc.contributor.authorAlfageme, Ien_US
dc.contributor.authorZalacain, Ren_US
dc.contributor.authorAlmirall, Jen_US
dc.contributor.authorMolinos, Len_US
dc.contributor.authorBello, Sen_US
dc.contributor.authorRodríguez de Castro, Felipe Carlos B.en_US
dc.contributor.authorBlanquer, J.en_US
dc.contributor.authorDorado, Aen_US
dc.contributor.authorLlevat, Nen_US
dc.contributor.authorRello, Jen_US
dc.date.accessioned2020-03-17T16:27:42Z-
dc.date.available2020-03-17T16:27:42Z-
dc.date.issued2015en_US
dc.identifier.issn0040-6376en_US
dc.identifier.urihttp://hdl.handle.net/10553/70951-
dc.description.abstractIntroduction Healthcare-associated pneumonia (HCAP) is actually considered a subgroup of hospital-acquired pneumonia due to the reported high risk of multidrug-resistant pathogens in the USA. Therefore, current American Thoracic Society/ Infectious Diseases Society of America guidelines suggest a nosocomial antibiotic treatment for HCAP. Unfortunately, the scientific evidence supporting this is contradictory. Methods We conducted a prospective multicentre case-control study in Spain, comparing clinical presentation, outcomes and microbial aetiology of HCAP and community-acquired pneumonia (CAP) patients matched by age (±10 years), gender and period of admission (±10 weeks). Results 476 patients (238 cases, 238 controls) were recruited for 2 years from June 2008. HCAP cases showed significantly more comorbidities (including dysphagia), higher frequency of previous antibiotic use in the preceding month, higher pneumonia severity score and worse clinical status (Charslon and Barthel scores). While microbial aetiology did not differ between the two groups (HCAP and CAP: Streptococcus pneumoniae: 51% vs 55%; viruses: 22% vs 12%; Legionella: 4% vs 9%; Gram-negative bacilli: 5% vs 4%; Pseudomonas aeruginosa: 4% vs 1%), HCAP patients showed worse mortality rates (1-month: HCAP, 12%; CAP 5%; 1-year: HCAP, 24%; CAP, 9%), length of hospital stay (9 vs 7 days), 1-month treatment failure (5.5% vs 1.5%) and readmission rate (18% vs 11%) (p<0.05, each). Conclusions Despite a similar clinical presentation, HCAP was more severe due to patients' conditions (comorbidities) and showed worse clinical outcomes. Microbial aetiology of HCAP did not differ from CAP indicating that it is not related to increased mortality and in Spain most HCAP patients do not need nosocomial antibiotic coverage.en_US
dc.languagespaen_US
dc.relation.ispartofThoraxen_US
dc.sourceThorax [ISSN 0040-6376], v. 68 (11), p. 1007-14en_US
dc.subject320103 Microbiología clínicaen_US
dc.titleErratum: Microbial aetiology of healthcare associated pneumonia in Spain: A prospective, multicentre, case-control study (Thorax (2013) 68 (1007-1014))en_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1136/thoraxjnl-2013-203828en_US
dc.identifier.pmid68-
dc.identifier.scopus2-s2.0-84939215389-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.description.lastpage1014-
dc.identifier.issue7-
dc.description.firstpage708-
dc.relation.volume70-
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.description.observacionesCorrección a: Thorax. 2013 Nov;68(11):1007-14. doi: 10.1136/thoraxjnl-2013-203828.en_US
dc.utils.revisionNoen_US
dc.identifier.ulpgces
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptPatología médica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameRodríguez De Castro, Felipe Carlos B.-
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