Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/70949
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dc.contributor.authorMontull, Beatrizen_US
dc.contributor.authorMenéndez, Rosarioen_US
dc.contributor.authorTorres, Antonien_US
dc.contributor.authorReyes, Soledaden_US
dc.contributor.authorMéndez, Raúlen_US
dc.contributor.authorZalacaín, Rafaelen_US
dc.contributor.authorCapelastegui, Albertoen_US
dc.contributor.authorRajas, Olgaen_US
dc.contributor.authorBorderías, Luisen_US
dc.contributor.authorMartin-Villasclaras, Juanen_US
dc.contributor.authorBello, Salvadoren_US
dc.contributor.authorAlfageme, Inmaculadaen_US
dc.contributor.authorRodríguez de Castro, Felipe Carlos B.en_US
dc.contributor.authorRello, Jordien_US
dc.contributor.authorMolinos, Luisen_US
dc.contributor.authorRuiz-Manzano, Juanen_US
dc.contributor.authorAspa, Javieren_US
dc.contributor.editorYende, Sachin-
dc.date.accessioned2020-03-17T16:11:42Z-
dc.date.available2020-03-17T16:11:42Z-
dc.date.issued2016en_US
dc.identifier.issn1932-6203en_US
dc.identifier.urihttp://hdl.handle.net/10553/70949-
dc.description.abstractBackground: Severe sepsis, may be present on hospital arrival in approximately one-third of patients with community-acquired pneumonia (CAP). Objective: To determine the host characteristics and micro-organisms associated with severe sepsis in patients hospitalized with CAP. Results: We performed a prospective multicenter cohort study in 13 Spanish hospital, on 4070 hospitalized CAP patients, 1529 of whom (37.6%) presented with severe sepsis. Severe sepsis CAP was independently associated with older age (>65 years), alcohol abuse (OR, 1.31; 95% CI, 1.07-1.61), chronic obstructive pulmonary disease (COPD) (OR, 1.75; 95% CI, 1.50-2.04) and renal disease (OR, 1.57; 95% CI, 1.21-2.03), whereas prior antibiotic treatment was a protective factor (OR, 0.62; 95% CI, 0.52-0.73). Bacteremia (OR, 1.37; 95% CI, 1.05-1.79), S pneumoniae (OR, 1.59; 95% CI, 1.31-1.95) and mixed microbial etiology (OR, 1.65; 95% CI, 1.10-2.49) were associated with severe sepsis CAP. Conclusions: CAP patients with COPD, renal disease and alcohol abuse, as well as those with CAP due to S pneumonia or mixed micro-organisms are more likely to present to the hospital with severe sepsis.en_US
dc.languageengen_US
dc.relation.ispartofPLoS ONEen_US
dc.sourcePLoS ONE [ISSN 1932-6203], v. 11 (1), e0145929en_US
dc.subject3207 Patologíaen_US
dc.subject.otherSevere sepsisen_US
dc.titlePredictors of severe sepsis among patients hospitalized for community-acquired pneumoniaen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1371/journal.pone.0145929en_US
dc.identifier.pmid11-
dc.identifier.scopus2-s2.0-84954069531-
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dc.contributor.authorscopusidYende, Sachin-
dc.contributor.authorscopusidYende, Sachin-
dc.identifier.issue1-
dc.description.firstpagee0145929-
dc.relation.volume11-
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.utils.revisionen_US
dc.identifier.ulpgces
dc.description.sjr1,201
dc.description.jcr2,806
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.fulltextCon texto completo-
item.grantfulltextopen-
crisitem.author.deptPatología médica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptCiencias Médicas y Quirúrgicas-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameRodríguez De Castro, Felipe Carlos B.-
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