Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/70509
DC FieldValueLanguage
dc.contributor.authorSayón-Orea, Carmenen_US
dc.contributor.authorRazquin, Cristinaen_US
dc.contributor.authorBulló, Mónicaen_US
dc.contributor.authorCorella, Doloresen_US
dc.contributor.authorFitó, Montserraten_US
dc.contributor.authorRomaguera, Doraen_US
dc.contributor.authorVioque, Jesúsen_US
dc.contributor.authorAlonso-Gómez, Ángel M.en_US
dc.contributor.authorWärnberg, Juliaen_US
dc.contributor.authorMartínez, J. Alfredoen_US
dc.contributor.authorSerra Majem, Luisen_US
dc.contributor.authorEstruch, Ramónen_US
dc.contributor.authorTinahones, Francisco J.en_US
dc.contributor.authorLapetra, Joséen_US
dc.contributor.authorPintó, Xavieren_US
dc.contributor.authorTur, Josep A.en_US
dc.contributor.authorLópez-Miranda, Joséen_US
dc.contributor.authorBueno-Cavanillas, Auroraen_US
dc.contributor.authorDelgado-Rodríguez, Miguelen_US
dc.contributor.authorMatía-Martín, Pilaren_US
dc.contributor.authorDaimiel, Lidiaen_US
dc.contributor.authorSánchez, Vicente Martínen_US
dc.contributor.authorVidal, Josepen_US
dc.contributor.authorVázquez, Clotildeen_US
dc.contributor.authorRos, Emilioen_US
dc.contributor.authorRuiz-Canela, Miguelen_US
dc.contributor.authorSorlí, José V.en_US
dc.contributor.authorCastañer, Olgaen_US
dc.contributor.authorFiol, Miquelen_US
dc.contributor.authorNavarrete-Muñoz, Eva M.en_US
dc.contributor.authorArós, Fernandoen_US
dc.contributor.authorGómez-Gracia, Enriqueen_US
dc.contributor.authorZulet, M. Angelesen_US
dc.contributor.authorSánchez Villegas, Almudenaen_US
dc.contributor.authorCasas, Rosaen_US
dc.contributor.authorBernal-López, Rosaen_US
dc.contributor.authorSantos-Lozano, José M.en_US
dc.contributor.authorCorbella, Emilien_US
dc.contributor.authorBouzas, Cristinaen_US
dc.contributor.authorGarcía-Arellano, Anaen_US
dc.contributor.authorBasora, Josepen_US
dc.contributor.authorAsensio, Eva M.en_US
dc.contributor.authorSchröder, Helmuten_US
dc.contributor.authorMoñino, Manuelen_US
dc.contributor.authorGarcía De La Hera, Manolien_US
dc.contributor.authorTojal-Sierra, Lucasen_US
dc.contributor.authorToledo, Estefaníaen_US
dc.contributor.authorDíaz-López, Andrésen_US
dc.contributor.authorGoday, Alberten_US
dc.contributor.authorSalas-Salvadó, Jordien_US
dc.contributor.authorMartínez-González, Miguel A.en_US
dc.date.accessioned2020-02-26T13:03:30Z-
dc.date.available2020-02-26T13:03:30Z-
dc.date.issued2019en_US
dc.identifier.issn0098-7484en_US
dc.identifier.urihttp://hdl.handle.net/10553/70509-
dc.description.abstractImportance: High-quality dietary patterns may help prevent chronic disease, but limited data exist from randomized trials about the effects of nutritional and behavioral interventions on dietary changes. Objective: To assess the effect of a nutritional and physical activity education program on dietary quality. Design, Setting, and Participants: Preliminary exploratory interim analysis of an ongoing randomized trial. In 23 research centers in Spain, 6874 men and women aged 55 to 75 years with metabolic syndrome and no cardiovascular disease were enrolled in the trial between September 2013 and December 2016, with final data collection in March 2019. Interventions: Participants were randomized to an intervention group that encouraged an energy-reduced Mediterranean diet, promoted physical activity, and provided behavioral support (n = 3406) or to a control group that encouraged an energy-unrestricted Mediterranean diet (n = 3468). All participants received allotments of extra-virgin olive oil (1 L/mo) and nuts (125 g/mo) for free. Main Outcomes and Measures: The primary outcome was 12-month change in adherence based on the energy-reduced Mediterranean diet (er-MedDiet) score (range, 0-17; higher scores indicate greater adherence; minimal clinically important difference, 1 point). Results: Among 6874 randomized participants (mean [SD] age, 65.0 [4.9] years; 3406 [52%] men), 6583 (96%) completed the 12-month follow-up and were included in the main analysis. The mean (SD) er-MedDiet score was 8.5 (2.6) at baseline and 13.2 (2.7) at 12 months in the intervention group (increase, 4.7 [95% CI, 4.6-4.8]) and 8.6 (2.7) at baseline and 11.1 (2.8) at 12 months in the control group (increase, 2.5 [95% CI, 2.3-2.6]) (between-group difference, 2.2 [95% CI, 2.1-2.4]; P <.001). Conclusions and Relevance: In this preliminary analysis of an ongoing trial, an intervention that encouraged an energy-reduced Mediterranean diet and physical activity, compared with advice to follow an energy-unrestricted Mediterranean diet, resulted in a significantly greater increase in diet adherence after 12 months. Further evaluation of long-term cardiovascular effects is needed. Trial Registration: isrctn.com Identifier: ISRCTN89898870.en_US
dc.languageengen_US
dc.relationEfecto de la Dieta Mediterránea Hopocalórica y Promoción de la Actividad Física en Prevención Primaria Cardiovascular.Estudio Piloto Sobre Marcadores Intermedios.en_US
dc.relationSistema Inmune Inespecífico en Dorada (Sparus Aurata): Activación Del Sistema Interferón y Papel de la Actividad Bh4. Pi042004/153en_US
dc.relationNeuroprotección Por Bloqueo de la Capacidad de Transactivadora Nf-Kb y Factores Relacionados.en_US
dc.relationEfecto de Una Intervención Intensiva de Pérdida de Peso Con Dieta Mediterránea Hipocalórica, Actividad Física y Tratamiento Conductual Sobre la Prevención Primaria Cardiovascular: Ensayo Predimed-Plusen_US
dc.relation.ispartofJAMA - Journal of the American Medical Associationen_US
dc.sourceJAMA - Journal of the American Medical Association [ISSN 0098-7484], v. 322 (15), p. 1486-1499en_US
dc.subject3206 Ciencias de la nutriciónen_US
dc.titleEffect of a Nutritional and Behavioral Intervention on Energy-Reduced Mediterranean Diet Adherence among Patients with Metabolic Syndrome: Interim Analysis of the PREDIMED-Plus Randomized Clinical Trialen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1001/jama.2019.14630en_US
dc.identifier.pmid322-
dc.identifier.scopus2-s2.0-85073182441-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.description.lastpage1499en_US
dc.identifier.issue15-
dc.description.firstpage1486en_US
dc.relation.volume322en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.ulpgces
dc.description.sjr5,913
dc.description.jcr45,54
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.project.principalinvestigatorSerra Majem, Luis-
crisitem.project.principalinvestigatorReal Valcárcel, Fernando-
crisitem.project.principalinvestigatorCastro López-Tarruella, Enrique-
crisitem.project.principalinvestigatorSerra Majem, Luis-
crisitem.author.deptGIR IUIBS: Nutrición-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.deptGIR IUIBS: Nutrición-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.orcid0000-0002-9658-9061-
crisitem.author.orcid0000-0001-7733-9238-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameSerra Majem, Luis-
crisitem.author.fullNameSánchez Villegas,Almudena-
Appears in Collections:Artículos
Show simple item record

Google ScholarTM

Check

Altmetric


Share



Export metadata



Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.