Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/69956
Title: The Comprehensive Complication Index is Related to Frailty in Elderly Surgical Patients
Authors: Artiles-Armas, Manuel
Roque-Castellano, Cristina 
Conde-Martel, Alicia 
Marchena-Gómez, Joaquín 
UNESCO Clasification: 32 Ciencias médicas
Keywords: Comprehensive Complication Index
Elderly
Frailty
Post-Operative Outcome
Issue Date: 2019
Journal: Journal of Surgical Research 
Abstract: Background: Frailty has been proposed as an independent risk factor for predicting postsurgical outcomes in elderly surgical patients. The Comprehensive Complication Index (CCI) seems to be the most widely used grading of individual complications in many surgical fields. The objective of this study was to evaluate the association of frailty, measured by Canadian Study of Health and Aging–Clinical Frailty Scale (CSHA-CFS), with the CCI in the elderly surgical patient. Material and methods: A prospective cross-sectional study was carried out in 256 patients aged ≥70 y who underwent major gastrointestinal surgery. Sociodemographic characteristics, baseline disease, CSHA-CFS, and medical/surgical complication using the Comprehensive Comorbidity Index were evaluated. We hypothesized that frailty measured by CSHA-CFS and the CCI are associated. Results: Of 256 patients, 154 (60%) were men and 102 (40%) were women, with mean age of 76.1 y (SD ± 5.1). One-hundred and eighty-five patients (74%) underwent surgery for a malignant cause, and 97 patients (38%) had some degree of frailty. Mean CCI was 16.1 (SD ± 23.0). Postoperative mortality was 3%. Pondering the scale CCI 0-100, frailty correlated well with postoperative complications (P = 0.035). For patients who developed at least 1 complication, for each unit that the CSHA-CFS was raised, the CCI increased by 5.2 points (P = 0.002). The multivariate analysis showed that the CSHA-CFS was the only independent prognostic factor associated with postoperative CCI in this series. Conclusions: Frailty determined by CSHA-CFS is closely associated with the CCI, being a good predictor of postoperative complications in the elderly patient operated on by a major gastrointestinal procedure.
URI: http://hdl.handle.net/10553/69956
ISSN: 0022-4804
DOI: 10.1016/j.jss.2019.06.011
Source: Journal of Surgical Research [ISSN 0022-4804], v. 244, p. 218-224
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