Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/69884
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dc.contributor.authorKonieczna, J.en_US
dc.contributor.authorYañez, A.en_US
dc.contributor.authorMoñino, M.en_US
dc.contributor.authorBabio, N.en_US
dc.contributor.authorToledo, E.en_US
dc.contributor.authorMartínez-González, M. A.en_US
dc.contributor.authorSorlí, J. V.en_US
dc.contributor.authorSalas-Salvadó, J.en_US
dc.contributor.authorEstruch, R.en_US
dc.contributor.authorRos, E.en_US
dc.contributor.authorAlonso-Gómez, A.en_US
dc.contributor.authorSchröder, H.en_US
dc.contributor.authorLapetra, J.en_US
dc.contributor.authorSerra-Majem, Llen_US
dc.contributor.authorPintó, X.en_US
dc.contributor.authorGutiérrez-Bedmar, M.en_US
dc.contributor.authorDíaz-López, A.en_US
dc.contributor.authorGonzález, J. I.en_US
dc.contributor.authorFitó, M.en_US
dc.contributor.authorForga, L.en_US
dc.contributor.authorFiol, M.en_US
dc.contributor.authorRomaguera, D.en_US
dc.date.accessioned2020-02-05T12:51:00Z-
dc.date.accessioned2020-04-24T16:19:45Z-
dc.date.available2020-02-05T12:51:00Z-
dc.date.available2020-04-24T16:19:45Z-
dc.date.issued2020en_US
dc.identifier.issn0261-5614en_US
dc.identifier.otherScopus-
dc.identifier.urihttp://hdl.handle.net/10553/69884-
dc.description.abstractLittle is known about the impact of specific dietary patterns on the development of obesity phenotypes. We aimed to determine the association of longitudinal changes in adherence to the traditional Mediterranean diet (MedDiet) with the transition between different obesity phenotypes. Methods: Data of 5801 older men and women at high cardiovascular risk from PREDIMED trial were used. Adherence to MedDiet was measured with the validated 14p-Mediterranean Diet Adherence Screener (MEDAS). Using the simultaneous combination of metabolic health- and body size-related parameters participants were categorized into one of four phenotypes: metabolically healthy and abnormal obese (MHO and MAO), metabolically healthy and abnormal non-obese (MHNO and MANO). Cox regression models with yearly repeated measures during 5-year of follow-up were built with use of Markov chain assumption. Results: Each 2-point increase in MEDAS was associated with the following transitions: in MAO participants, with a 16% (95% CI 3–31%) greater likelihood of becoming MHO; in MHO participants with a 14% (3–23%) lower risk of becoming MAO; in MHNO participants with a 18% (5–30%) lower risk of becoming MHO. In MANO women, but not in men, MEDAS was associated with 20% (5–38%) greater likely of becoming MHNO (p for interaction by gender 0.014). No other significant associations were observed. Conclusions: Better adherence to the traditional MedDiet is associated with transitions to healthier phenotypes, promoting metabolic health improvement in MAO, MANO (only in women), and MHO, as well as protecting against obesity incidence in MHNO subjects.en_US
dc.languageengen_US
dc.relation.ispartofClinical Nutritionen_US
dc.sourceClinical Nutrition [ISSN 0261-5614], v. 39(3), p. 966-975, (Marzo 2020)en_US
dc.subject3206 Ciencias de la nutriciónen_US
dc.subject320610 Enfermedades de la nutriciónen_US
dc.subject.otherMediterranean Dieten_US
dc.subject.otherMetabolically Abnormal Non-Obeseen_US
dc.subject.otherMetabolically Healthy Obeseen_US
dc.subject.otherObesity Phenotypesen_US
dc.subject.otherThe Predimed Trialen_US
dc.subject.otherTransition Probabilitiesen_US
dc.titleLongitudinal changes in Mediterranean diet and transition between different obesity phenotypesen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.clnu.2019.04.002en_US
dc.identifier.scopus85064905093-
dc.contributor.authorscopusid57210305858-
dc.contributor.authorscopusid7005888909-
dc.contributor.authorscopusid14120071900-
dc.contributor.authorscopusid24279242400-
dc.contributor.authorscopusid7003562288-
dc.contributor.authorscopusid7004290629-
dc.contributor.authorscopusid7004605575-
dc.contributor.authorscopusid7003357665-
dc.contributor.authorscopusid7005989830-
dc.contributor.authorscopusid57202558933-
dc.contributor.authorscopusid7004308784-
dc.contributor.authorscopusid35280719100-
dc.contributor.authorscopusid6507771144-
dc.contributor.authorscopusid57202560799-
dc.contributor.authorscopusid57208932373-
dc.contributor.authorscopusid6506505275-
dc.contributor.authorscopusid55195487000-
dc.contributor.authorscopusid57192590236-
dc.contributor.authorscopusid57206229124-
dc.contributor.authorscopusid6603432597-
dc.contributor.authorscopusid7005315313-
dc.contributor.authorscopusid8161433300-
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.utils.revisionen_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr1,915
dc.description.jcr7,324
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR IUIBS: Nutrición-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.orcid0000-0002-9658-9061-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameSerra Majem, Luis-
Colección:Artículos
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