Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/69831
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dc.contributor.authorLópez, Sergioen_US
dc.contributor.authorVilar Guereño, José Manuelen_US
dc.contributor.authorSopena, Joaquín J.en_US
dc.contributor.authorDamià, Elenaen_US
dc.contributor.authorChicharro, Deborahen_US
dc.contributor.authorCarrillo, José M.en_US
dc.contributor.authorCuervo, Belénen_US
dc.contributor.authorRubio, Mónicaen_US
dc.date.accessioned2020-02-05T12:50:29Z-
dc.date.available2020-02-05T12:50:29Z-
dc.date.issued2019en_US
dc.identifier.issn1661-6596en_US
dc.identifier.otherScopus-
dc.identifier.urihttp://hdl.handle.net/10553/69831-
dc.description.abstractThe role of platelet-rich plasma (PRP) in promoting the healing of bone fractures has not yet been clearly stated. The aim of this prospective clinical study was to evaluate the effectiveness of plasma rich in growth factors (PRGF, a PRP derivate) in the treatment of naturally-occurring bone fractures in dogs. With this objective, sixty-five dogs with radius/ulna or tibia/fibula bone fractures were randomly divided into two groups (PRGF and saline solution (SS) groups) and checked at days 0, 7, 14, 21, 28, 35, 42, 49, 56, 60, 63, 70, 120, and 180. All the fractures were treated with an external skeletal fixation, and pain was controlled with Carprofen. Healing was evaluated by physical examination, limb function, radiography, and by a Likert-type owner satisfaction questionnaire. A faster fracture healing was observed in the PRGF group, with statistically significant differences with respect to the SS group. Swelling at the fracture site was significantly greater at day 14 and 28 in animals injected with PRGF, and more pain on palpation was found in the area at day 28. The injection of PRGF in acute bone fractures accelerates bone healing.en_US
dc.languageengen_US
dc.relation.ispartofInternational Journal of Molecular Sciencesen_US
dc.sourceInternational Journal of Molecular Sciences [ISSN 1661-6596], v. 20 (5), 1075en_US
dc.subject310907 Patologíaen_US
dc.subject321315 Traumatologíaen_US
dc.subject.otherBone Healingen_US
dc.subject.otherCarprofenen_US
dc.subject.otherDogen_US
dc.subject.otherFractureen_US
dc.subject.otherPRGFen_US
dc.titleAssessment of the efficacy of platelet-rich plasma in the treatment of traumatic canine fracturesen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.3390/ijms20051075en_US
dc.identifier.scopus85062392049-
dc.identifier.isi000462542300074-
dc.contributor.authorscopusid57202814771-
dc.contributor.authorscopusid7005533720-
dc.contributor.authorscopusid9534772600-
dc.contributor.authorscopusid57190564644-
dc.contributor.authorscopusid57202814470-
dc.contributor.authorscopusid37071989800-
dc.contributor.authorscopusid57194687048-
dc.contributor.authorscopusid9532488300-
dc.identifier.issue5-
dc.relation.volume20en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.contributor.daisngid2521996-
dc.contributor.daisngid913655-
dc.contributor.daisngid2284901-
dc.contributor.daisngid6343311-
dc.contributor.daisngid27576083-
dc.contributor.daisngid30324417-
dc.contributor.daisngid7071963-
dc.contributor.daisngid1882833-
dc.description.notasThis article belongs to the Special Issue Blood-Derived Products for Tissue Repair/Regenerationen_US
dc.description.numberofpages10en_US
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Lopez, S-
dc.contributor.wosstandardWOS:Vilar, JM-
dc.contributor.wosstandardWOS:Sopena, JJ-
dc.contributor.wosstandardWOS:Damia, E-
dc.contributor.wosstandardWOS:Chicharro, D-
dc.contributor.wosstandardWOS:Carrillo, JM-
dc.contributor.wosstandardWOS:Cuervo, B-
dc.contributor.wosstandardWOS:Rubio, M-
dc.date.coverdateMarzo 2019en_US
dc.identifier.ulpgces
dc.description.sjr1,317
dc.description.jcr4,556
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.fulltextCon texto completo-
item.grantfulltextopen-
crisitem.author.deptGIR IUIBS: Medicina Veterinaria e Investigación Terapéutica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.orcid0000-0002-2060-2274-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameVilar Guereño, José Manuel-
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