Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/69321
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dc.contributor.authorAlemán-Domínguez, M. E.en_US
dc.contributor.authorOrtega, Z.en_US
dc.contributor.authorBenitez, A. N.en_US
dc.contributor.authorMonzón, Marioen_US
dc.contributor.authorGarzon, L., Ven_US
dc.contributor.authorAjami, Saraen_US
dc.contributor.authorLiu, Chaozongen_US
dc.date.accessioned2020-01-24T10:30:40Z-
dc.date.available2020-01-24T10:30:40Z-
dc.date.issued2018en_US
dc.identifier.issn2096-5524en_US
dc.identifier.otherWoS-
dc.identifier.urihttp://hdl.handle.net/10553/69321-
dc.description.abstractPolycaprolactone-carboxymethyl cellulose composites have been obtained and used to print porous structures by material extrusion. The materials used contained 0, 2 and 5% w/w of the carboxymethyl cellulose additive. These structures have been analyzed in terms of their morphology (including the evaluation of their porosity), mechanical properties under compression load and cell affinity. Cell affinity has been evaluated by culturing sheep mesenchymal stem cells and analyzing their viability by the Alamar Blue (R) assay at days 1, 3, 6 and 8. The results show that composites samples have similar values of porosity and apparent density than pure polycaprolactone ones. However, samples containing 5% w/w of carboxymethyl cellulose have micropores on the filaments due to a hindered deposition process. This characteristic affects the mechanical properties of the structures, so these ones have a mean compression modulus significantly lower than pure polycaprolactone scaffolds. However, the samples containing 2% w/w of carboxymethyl cellulose show no significant difference with the pure polycaprolactone ones in terms of their mechanical properties. Moreover, the presence of 2% w/w of additive improves cell proliferation on the surface of the porous structures. As complementary information, the flow properties of the composite materials were studied and the power law equations at 210 degrees C obtained, as this temperature was the 3D printing temperature. These equations can be useful for simulation and designing purposes of other manufacturing processes.en_US
dc.languageengen_US
dc.relation.ispartofBio-design and manufacturingen_US
dc.sourceBio-Design And Manufacturing[ISSN 2096-5524],v. 1 (4), p. 245-253en_US
dc.subject3303 ingeniería y tecnología químicasen_US
dc.subject.otherFiber-Deposited Scaffoldsen_US
dc.subject.otherMechanical-Propertiesen_US
dc.subject.otherIn-Vitroen_US
dc.subject.otherBiomaterialsen_US
dc.subject.otherBehavioren_US
dc.subject.otherHydroxyapatiteen_US
dc.subject.otherArchitectureen_US
dc.subject.otherFabricationen_US
dc.subject.otherFlowen_US
dc.titlePolycaprolactone-carboxymethyl cellulose composites for manufacturing porous scaffolds by material extrusionen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1007/s42242-018-0024-z
dc.identifier.scopus85062724136
dc.identifier.isi000452718500004-
dc.contributor.authorscopusid56097219900
dc.contributor.authorscopusid36241994700
dc.contributor.authorscopusid57210096811
dc.contributor.authorscopusid7003371153
dc.contributor.authorscopusid57207692052
dc.contributor.authorscopusid57188743870
dc.contributor.authorscopusid57188879979
dc.identifier.eissn2522-8552-
dc.description.lastpage253-
dc.identifier.issue4-
dc.description.firstpage245-
dc.relation.volume1-
dc.investigacionIngeniería y Arquitecturaen_US
dc.type2Artículoen_US
dc.contributor.daisngid8698575
dc.contributor.daisngid2273115
dc.contributor.daisngid579452
dc.contributor.daisngid1363424
dc.contributor.daisngid24433207
dc.contributor.daisngid11749117
dc.contributor.daisngid29692247
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Aleman-Dominguez, ME
dc.contributor.wosstandardWOS:Ortega, Z
dc.contributor.wosstandardWOS:Benitez, AN
dc.contributor.wosstandardWOS:Monzon, M
dc.contributor.wosstandardWOS:Garzon, LV
dc.contributor.wosstandardWOS:Ajami, S
dc.contributor.wosstandardWOS:Liu, CZ
dc.date.coverdateDiciembre 2018
dc.identifier.ulpgces
dc.description.esciESCI
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR Fabricación integrada y avanzada-
crisitem.author.deptDepartamento de Ingeniería de Procesos-
crisitem.author.deptGIR Fabricación integrada y avanzada-
crisitem.author.deptDepartamento de Ingeniería de Procesos-
crisitem.author.deptGIR Fabricación integrada y avanzada-
crisitem.author.deptDepartamento de Ingeniería Mecánica-
crisitem.author.orcid0000-0002-2254-9905-
crisitem.author.orcid0000-0002-7112-1067-
crisitem.author.orcid0000-0001-5711-6395-
crisitem.author.orcid0000-0003-2736-7905-
crisitem.author.parentorgDepartamento de Ingeniería Mecánica-
crisitem.author.parentorgDepartamento de Ingeniería Mecánica-
crisitem.author.parentorgDepartamento de Ingeniería Mecánica-
crisitem.author.fullNameAlemán Domínguez, María Elena-
crisitem.author.fullNameOrtega Medina, Zaida Cristina-
crisitem.author.fullNameBenítez Vega, Antonio Nizardo-
crisitem.author.fullNameMonzón Verona, Mario Domingo-
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