Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/6568
DC FieldValueLanguage
dc.contributor.authorGonzález-Alonso, J.-
dc.contributor.authorCalbet, JAL-
dc.contributor.authorNielsen, Bodil-
dc.contributor.otherCalbet, Jose A-
dc.date.accessioned2011-11-02T02:31:00Z-
dc.date.accessioned2018-03-08T13:12:01Z-
dc.date.available2011-11-02T13:45:07Z-
dc.date.available2018-03-08T13:12:01Z-
dc.date.issued1998-
dc.identifier.issn0022-3751-
dc.identifier.urihttp://hdl.handle.net/10553/6568-
dc.description.abstract1. The present study examined whether the blood flow to exercising muscles becomes reduced when cardiac output and systemic vascular conductance decline with dehydration during prolonged exercise in the heat. A secondary aim was to determine whether the upward drift in oxygen consumption (VO2) during prolonged exercise is confined to the active muscles. 2. Seven euhydrated, endurance-trained cyclists performed two bicycle exercise trials in the heat (35 C; 40-50 % relative humidity; 61 +/- 2 % of maximal VO2), separated by 1 week. During the first trial (dehydration trial, DE), they bicycled until volitional exhaustion (135 +/- 4 min, mean +/- s.e.m.), while developing progressive dehydration and hyperthermia (3.9 +/- 0.3 % body weight loss; 39.7 +/- 0.2 C oesophageal temperature, Toes). In the second trial (control trial), they bicycled for the same period of time while maintaining euhydration by ingesting fluids and stabilizing Toes at 38.2 +/- 0.1 C after 30 min exercise. 3. In both trials, cardiac output, leg blood flow (LBF), vascular conductance and VO2 were similar after 20 min exercise. During the 20 min-exhaustion period of DE, cardiac output, LBF and systemic vascular conductance declined significantly (8-14 %; P < 0.05) yet muscle vascular conductance was unaltered. In contrast, during the same period of control, all these cardiovascular variables tended to increase. After 135 +/- 4 min of DE, the 2.0 +/- 0.6 l min-1 lower blood flow to the exercising legs accounted for approximately two-thirds of the reduction in cardiac output. Blood flow to the skin also declined markedly as forearm blood flow was 39 +/- 8 % (P < 0.05) lower in DE vs. control after 135 +/- 4 min. 4. In both trials, whole body VO2 and leg VO2 increased in parallel and were similar throughout exercise. The reduced leg blood flow in DE was accompanied by an even greater increase in femoral arterial-venous O2 (a-vO2) difference. 5. It is concluded that blood flow to the exercising muscles declines significantly with dehydration, due to a lowering in perfusion pressure and systemic blood flow rather than increased vasoconstriction. Furthermore, the progressive increase in oxygen consumption during exercise is confined to the exercising skeletal muscles.es
dc.languageenges
dc.relation.ispartofJournal of Physiologyes-ES
dc.sourceJournal Of Physiology [ISSN 0022-3751],v. 513 (3), p. 895-905es
dc.subject241106 Fisiología del ejercicioes
dc.subject.otherHeates
dc.subject.otherBlood flowes
dc.subject.otherDehydrationes
dc.subject.otherExercisees
dc.titleMuscle blood flow is reduced with dehydration during prolonged exercise in humanses
dc.typeinfo:eu-repo/semantics/Articlees
dc.typeArticlees
dc.identifier.doi10.1111/j.1469-7793.1998.895ba.x
dc.identifier.scopus0032535322
dc.identifier.isi000078017800023-
dcterms.isPartOfJournal Of Physiology-London-
dcterms.sourceJournal Of Physiology-London[ISSN 0022-3751],v. 513 (3), p. 895-905-
dc.contributor.authorscopusid7004397216
dc.contributor.authorscopusid7004323423
dc.contributor.authorscopusid35596284500
dc.identifier.crisid-;475;--
dc.description.lastpage905-
dc.description.firstpage895-
dc.relation.volume513-
dc.investigacionCiencias de la Saludes
dc.rights.accessrightsinfo:eu-repo/semantics/openAccesses
dc.type2Artículoes
dc.identifier.wosWOS:000078017800023-
dc.contributor.daisngid9620399-
dc.contributor.daisngid90295-
dc.contributor.daisngid3221754-
dc.identifier.investigatorRIDH-6693-2015-
dc.date.coverdateDiciembre 1998
item.grantfulltextopen-
item.fulltextCon texto completo-
crisitem.author.deptDepartamento de Educación Física-
crisitem.author.deptRendimiento humano, ejercicio físico y salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.orcid0000-0002-9215-6234-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameLópez Calbet, José Antonio-
crisitem.author.departamentoEducación Física-
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