Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/55753
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dc.contributor.authorGalaz, Zoltanen_US
dc.contributor.authorMekyska, Jirien_US
dc.contributor.authorZvoncak, Vojtechen_US
dc.contributor.authorMucha, Janen_US
dc.contributor.authorKiska, Tomasen_US
dc.contributor.authorSmekal, Zdeneken_US
dc.contributor.authorEliasova, Ilonaen_US
dc.contributor.authorMrackova, Martinaen_US
dc.contributor.authorKostalova, Milenaen_US
dc.contributor.authorRektorova, Irenaen_US
dc.contributor.authorFaundez-Zanuy, Marcosen_US
dc.contributor.authorAlonso Hernández, Jesús Bernardinoen_US
dc.contributor.authorGomez-Vilda, Pedroen_US
dc.date.accessioned2019-06-10T21:44:51Z-
dc.date.available2019-06-10T21:44:51Z-
dc.date.issued2018en_US
dc.identifier.issn2076-3417en_US
dc.identifier.otherWoS-
dc.identifier.urihttp://hdl.handle.net/10553/55753-
dc.description.abstractHypokinetic dysarthria, which is associated with Parkinson's disease (PD), affects several speech dimensions, including phonation. Although the scientific community has dealt with a quantitative analysis of phonation in PD patients, a complex research revealing probable relations between phonatory features and progress of PD is missing. Therefore, the aim of this study is to explore these relations and model them mathematically to be able to estimate progress of PD during a two-year follow-up. We enrolled 51 PD patients who were assessed by three commonly used clinical scales. In addition, we quantified eight possible phonatory disorders in five vowels. To identify the relationship between baseline phonatory features and changes in clinical scores, we performed a partial correlation analysis. Finally, we trained XGBoost models to predict the changes in clinical scores during a two-year follow-up. For two years, the patients' voices became more aperiodic with increased microperturbations of frequency and amplitude. Next, the XGBoost models were able to predict changes in clinical scores with an error in range 11-26%. Although we identified some significant correlations between changes in phonatory features and clinical scores, they are less interpretable. This study suggests that it is possible to predict the progress of PD based on the acoustic analysis of phonation. Moreover, it recommends utilizing the sustained vowel /i/ instead of /a/.en_US
dc.languageengen_US
dc.relation.ispartofApplied Sciences (Basel)en_US
dc.sourceApplied Sciences (Basel) [ISSN 2076-3417], v. 8 (12), 2339, (2018)en_US
dc.subject3307 Tecnología electrónicaen_US
dc.subject.otherPhonationen_US
dc.subject.otherAcoustic analysisen_US
dc.subject.otherFollow-up studyen_US
dc.subject.otherHypokinetic dysarthriaen_US
dc.subject.otherParkinson’s diseaseen_US
dc.titleChanges in phonation and their relations with progress of Parkinson's diseaseen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.3390/app8122339en_US
dc.identifier.scopus85057112571-
dc.identifier.isi000455145000007-
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dc.contributor.authorscopusid56888706700-
dc.contributor.authorscopusid35746344400-
dc.contributor.authorscopusid57201027097-
dc.contributor.authorscopusid57201029686-
dc.contributor.authorscopusid57192544834-
dc.contributor.authorscopusid36855362600-
dc.contributor.authorscopusid55524322100-
dc.contributor.authorscopusid24598046000-
dc.contributor.authorscopusid15044536700-
dc.contributor.authorscopusid6603054591-
dc.contributor.authorscopusid6701452104-
dc.contributor.authorscopusid57195466969-
dc.contributor.authorscopusid6507800333-
dc.identifier.issue12-
dc.relation.volume8en_US
dc.investigacionIngeniería y Arquitecturaen_US
dc.type2Artículoen_US
dc.contributor.daisngid3828823-
dc.contributor.daisngid1102140-
dc.contributor.daisngid9955641-
dc.contributor.daisngid223658-
dc.contributor.daisngid7689834-
dc.contributor.daisngid355338-
dc.contributor.daisngid2834636-
dc.contributor.daisngid2427358-
dc.contributor.daisngid1551952-
dc.contributor.daisngid157722-
dc.contributor.daisngid259157-
dc.contributor.daisngid29084685-
dc.contributor.daisngid30347157-
dc.description.notasThis article belongs to the Special Issue Selected Papers from the 2018 41st International Conference on Telecommunications and Signal Processing (TSP)en_US
dc.description.numberofpages18en_US
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Galaz, Z-
dc.contributor.wosstandardWOS:Mekyska, J-
dc.contributor.wosstandardWOS:Zvoncak, V-
dc.contributor.wosstandardWOS:Mucha, J-
dc.contributor.wosstandardWOS:Kiska, T-
dc.contributor.wosstandardWOS:Smekal, Z-
dc.contributor.wosstandardWOS:Eliasova, I-
dc.contributor.wosstandardWOS:Mrackova, M-
dc.contributor.wosstandardWOS:Kostalova, M-
dc.contributor.wosstandardWOS:Rektorova, I-
dc.contributor.wosstandardWOS:Faundez-Zanuy, M-
dc.contributor.wosstandardWOS:Alonso-Hernandez, JB-
dc.contributor.wosstandardWOS:Gomez-Vilda, P-
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-TELen_US
dc.description.sjr0,379
dc.description.jcr2,217
dc.description.sjrqQ1
dc.description.jcrqQ2
dc.description.scieSCIE
item.fulltextCon texto completo-
item.grantfulltextopen-
crisitem.author.deptGIR IDeTIC: División de Procesado Digital de Señales-
crisitem.author.deptIU para el Desarrollo Tecnológico y la Innovación-
crisitem.author.deptDepartamento de Señales y Comunicaciones-
crisitem.author.orcid0000-0002-7866-585X-
crisitem.author.parentorgIU para el Desarrollo Tecnológico y la Innovación-
crisitem.author.fullNameAlonso Hernández, Jesús Bernardino-
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