Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/53956
DC FieldValueLanguage
dc.contributor.authorCentol, I.en_US
dc.contributor.authorDeniz, A.en_US
dc.contributor.authorBenitez, L.en_US
dc.contributor.authorMarrero, I.en_US
dc.contributor.authorFanjul, L. F.en_US
dc.contributor.authorRuiz de Galarreta, C. M.en_US
dc.contributor.otherMarrero-Arencibia, Isabel-
dc.date.accessioned2019-02-04T18:59:48Z-
dc.date.available2019-02-04T18:59:48Z-
dc.date.issued1988en_US
dc.identifier.issn0158-5231en_US
dc.identifier.urihttp://hdl.handle.net/10553/45316-
dc.description.abstractTesticular cells from adult hypophysectomized rats were cultured for 10 or 12 days, and the effect of treatment with hCG (10 ng/ml) on testosterone and progesterone production and the activity of the Leydig cell enzyme, 3 beta-hydroxysteroid dehydrogenase, were studied. Regardless of hormone treatment, on 4th day in culture a decline in the steroidogenic activity of cultured cells could be observed. Treatment with hCG resulted in stimulation of steroidogenesis on days 6 to 10 in culture, as measured by testosterone and progesterone production. Hormone treatment stimulated or inhibited the enzyme activity depending on the presence or absence in the culture medium of 10(-6) M spironolactone, an inhibitor of 17 alpha-hydroxylase, or an anti-androgen, cyproterone acetate.en_US
dc.languageengen_US
dc.relation.ispartofBiochemistry Internationalen_US
dc.sourceBiochemistry International [ISSN 0158-5231], v. 16 (2), p. 311-322en_US
dc.subject32 Ciencias médicasen_US
dc.subject2403 Bioquímicaen_US
dc.subject.otherFunctional activityen_US
dc.subject.otherTesticular cellsen_US
dc.titleFunctional activity of rat testicular cells in cultureen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.scopus0023958465-
dc.identifier.isiA1988M411500015-
dcterms.isPartOfBiochemistry International-
dcterms.sourceBiochemistry International[ISSN 0158-5231],v. 16 (2), p. 311-322-
dc.contributor.authorscopusid6505759813-
dc.contributor.authorscopusid7004186223-
dc.contributor.authorscopusid7004409333-
dc.contributor.authorscopusid35936487800-
dc.contributor.authorscopusid7004158812-
dc.contributor.authorscopusid7003806034-
dc.description.lastpage322en_US
dc.identifier.issue2-
dc.description.firstpage311en_US
dc.relation.volume16en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.wosWOS:A1988M411500015-
dc.contributor.daisngid8461416-
dc.contributor.daisngid265045-
dc.contributor.daisngid555851-
dc.contributor.daisngid3844163-
dc.contributor.daisngid1127140-
dc.contributor.daisngid1664323-
dc.identifier.investigatorRIDQ-9437-2016-
dc.description.numberofpages12en_US
dc.utils.revisionen_US
dc.date.coverdateFebrero 1988en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR IUIBS: Bioquímica Farmacológica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología.-
crisitem.author.deptDepartamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología.-
crisitem.author.orcid0000-0003-3732-9929-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameMarrero Arencibia, María Isabel-
crisitem.author.fullNameFanjul Rodríguez, Luisa Fernanda-
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