Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/53478
Campo DC Valoridioma
dc.contributor.authorTorrecillas Burriel,Silviaen_US
dc.contributor.authorMontero, Danielen_US
dc.contributor.authorJose Caballero, Mariaen_US
dc.contributor.authorPittman, Karin A.en_US
dc.contributor.authorCustodio, Marcoen_US
dc.contributor.authorCampo, Auroraen_US
dc.contributor.authorSweetman, Johnen_US
dc.contributor.authorIzquierdo, Marisolen_US
dc.contributor.otherTorrecillas, Silvia-
dc.contributor.otherCaballero, Maria Jose-
dc.contributor.otherCustodio, Marco-
dc.contributor.otherMontero, Daniel-
dc.contributor.otherIzquierdo, Marisol-
dc.date.accessioned2019-02-04T16:50:11Z-
dc.date.available2019-02-04T16:50:11Z-
dc.date.issued2015en_US
dc.identifier.issn1664-3224en_US
dc.identifier.urihttp://hdl.handle.net/10553/53478-
dc.description.abstractThe main objective of this study was to assess the effects of 4 g kg−1 dietary mannan oligosaccharides (MOS) inclusion in soybean oil (SBO)- and fish oil (FO)-based diets on the gut health and skin mucosa mucus production of European sea bass juveniles after 8 weeks of feeding. Dietary MOS, regardless of the oil source, promoted growth. The intestinal somatic index was not affected, however dietary SBO reduced the intestinal fold length, while dietary MOS increased it. The dietary oil source fed produced changes on the posterior intestine fatty acid profiles irrespective of MOS dietary supplementation. SBO down-regulated the gene expression of TCRβ, COX2, IL-1β, TNFα, IL-8, IL-6, IL-10, TGFβ, and Ig and up-regulated MHCII. MOS supplementation up-regulated the expression of MHCI, CD4, COX2, TNFα, and Ig when included in FO-based diets. However, there was a minor up-regulating effect on these genes when MOS was supplemented in the SBO-based diet. Both dietary oil sources and MOS affected mean mucous cell areas within the posterior gut, however the addition of MOS to a SBO diet increased the mucous cell size over the values shown in FO fed fish. Dietary SBO also trends to reduce mucous cell density in the anterior gut relative to FO, suggesting a lower overall mucosal secretion. There are no effects of dietary oil or MOS in the skin mucosal patterns. Complete replacement of FO by SBO, modified the gut fatty acid profile, altered posterior gut-associated immune system (GALT)-related gene expression and gut mucous cells patterns, induced shorter intestinal folds and tended to reduce European sea bass growth. However, when combined with MOS, the harmful effects of SBO appear to be partially balanced by moderating the down-regulation of certain GALT-related genes involved in the functioning of gut mucous barrier and increasing posterior gut mucous cell diffusion rates, thus helping to preserve immune homeostasis. This denotes the importance of a balanced dietary n–3/n–6 ratio for an appropriate GALT-immune response against MOS in European sea bass juveniles.en_US
dc.languageengen_US
dc.relation.ispartofFrontiers in Immunologyen_US
dc.sourceFrontiers In Immunology [ISSN 1664-3224], v. 6, 397en_US
dc.subject2510 Oceanografíaen_US
dc.subject.otherFatty-Acid-Composition
dc.subject.otherSalmon Salmo-Salar
dc.subject.otherSalvelinus-Alpinus L.
dc.subject.otherIntestinal Epithelial-Cells
dc.subject.otherTurbot Scophthalmus-Maximus
dc.subject.otherTrout Oncorhynchus-Mykiss
dc.subject.otherVegetable Lipid Sources
dc.subject.otherSeabream Sparus-Aurata
dc.subject.otherBrush-Border Membrane
dc.subject.otherTumor-Necrosis-Factor
dc.titleDietary mannan oligosaccharides: counteracting the side effects of soybean meal oil inclusion on european sea bass (Dicentrarchus labrax) gut health and skin mucosa mucus production?en_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.3389/fimmu.2015.00397
dc.identifier.scopus84938541648-
dc.identifier.isi000359469500001-
dcterms.isPartOfFrontiers In Immunology-
dcterms.sourceFrontiers In Immunology[ISSN 1664-3224],v. 6-
dc.contributor.authorscopusid21733894700-
dc.contributor.authorscopusid35605929400-
dc.contributor.authorscopusid7102935199-
dc.contributor.authorscopusid8948324400-
dc.contributor.authorscopusid57196586420-
dc.contributor.authorscopusid56754908900-
dc.contributor.authorscopusid34882169900-
dc.contributor.authorscopusid7103111891-
dc.identifier.issue397-
dc.relation.volume6-
dc.investigacionCienciasen_US
dc.type2Artículoen_US
dc.identifier.wosWOS:000359469500001-
dc.contributor.daisngid1545065-
dc.contributor.daisngid233847-
dc.contributor.daisngid436538-
dc.contributor.daisngid131253-
dc.contributor.daisngid8868207-
dc.contributor.daisngid7627798-
dc.contributor.daisngid685263-
dc.contributor.daisngid31444473
dc.contributor.daisngid1047053-
dc.identifier.investigatorRIDF-5378-2016-
dc.identifier.investigatorRIDJ-6599-2017-
dc.identifier.investigatorRIDC-8372-2017-
dc.identifier.investigatorRIDO-7108-2015-
dc.identifier.investigatorRIDNo ID-
dc.contributor.wosstandardWOS:Torrecillas, S
dc.contributor.wosstandardWOS:Montero, D
dc.contributor.wosstandardWOS:Caballero, MJ
dc.contributor.wosstandardWOS:Pittman, KA
dc.contributor.wosstandardWOS:Custodio, M
dc.contributor.wosstandardWOS:Campo, A
dc.contributor.wosstandardWOS:Sweetman, J
dc.contributor.wosstandardWOS:Izquierdo, M
dc.date.coverdateAgosto 2015
dc.identifier.ulpgces
dc.description.sjr2,818
dc.description.jcr5,695
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.grantfulltextopen-
item.fulltextCon texto completo-
crisitem.author.deptGIR Grupo de Investigación en Acuicultura-
crisitem.author.deptIU de Investigación en Acuicultura Sostenible y Ec-
crisitem.author.deptGIR Grupo de Investigación en Acuicultura-
crisitem.author.deptIU de Investigación en Acuicultura Sostenible y Ec-
crisitem.author.deptDepartamento de Biología-
crisitem.author.deptGIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina)-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.deptGIR Grupo de Investigación en Acuicultura-
crisitem.author.deptIU de Investigación en Acuicultura Sostenible y Ec-
crisitem.author.deptDepartamento de Biología-
crisitem.author.orcid0000-0002-4358-2157-
crisitem.author.orcid0000-0002-2575-0997-
crisitem.author.orcid0000-0003-4297-210X-
crisitem.author.parentorgIU de Investigación en Acuicultura Sostenible y Ec-
crisitem.author.parentorgIU de Investigación en Acuicultura Sostenible y Ec-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Investigación en Acuicultura Sostenible y Ec-
crisitem.author.fullNameTorrecillas Burriel,Silvia-
crisitem.author.fullNameMontero Vítores, Daniel-
crisitem.author.fullNameCaballero Cansino, María José-
crisitem.author.fullNameIzquierdo López, María Soledad-
Colección:Artículos
miniatura
pdf
Adobe PDF (2,24 MB)
Vista resumida

Citas SCOPUSTM   

53
actualizado el 24-mar-2024

Citas de WEB OF SCIENCETM
Citations

49
actualizado el 25-feb-2024

Visitas

83
actualizado el 03-feb-2024

Descargas

88
actualizado el 03-feb-2024

Google ScholarTM

Verifica

Altmetric


Comparte



Exporta metadatos



Los elementos en ULPGC accedaCRIS están protegidos por derechos de autor con todos los derechos reservados, a menos que se indique lo contrario.