Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/53431
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Torres-Peralta, Rafael | en_US |
dc.contributor.author | Guadalupe Grau, Amelia | en_US |
dc.contributor.author | Rodríguez-García, Lorena | en_US |
dc.contributor.author | Morales Alamo, David | en_US |
dc.contributor.author | Ponce-González, Jesús Gustavo | en_US |
dc.contributor.author | Pérez-Suarez, Ismael | en_US |
dc.contributor.author | Santana Rodríguez, Alfredo | en_US |
dc.contributor.author | López Calbet, José Antonio | en_US |
dc.contributor.other | Ponce Gonzalez, Jesus Gustavo | - |
dc.contributor.other | Morales-Alamo, David | - |
dc.contributor.other | Guadalupe-Grau, Amelia | - |
dc.contributor.other | Sanchez de Torres-Peralta, Rafael | - |
dc.date.accessioned | 2019-02-04T16:37:18Z | - |
dc.date.available | 2019-02-04T16:37:18Z | - |
dc.date.issued | 2016 | en_US |
dc.identifier.issn | 1746-1391 | en_US |
dc.identifier.uri | http://hdl.handle.net/10553/52526 | - |
dc.description.abstract | Objectives: This study was designed to investigate the association of gender, fibre type composition, and anaerobic performance with the basal skeletal muscle signalling cascades regulating muscle phenotype. Design: Muscle biopsies were obtained from 25 men and 10 women all young and healthy. Methods. Protein phosphorylation of Thr172AMPKα, Ser221ACCβ, Thr286CaMKII as well as total protein abundance of PGC-1α, SIRT1, and CnA were measured by Western blot and anaerobic performance by the Wingate test. Results: Percent type I myosin heavy chain (MHC I) was lower in men (37.1 ± 10.4 vs. 58.5 ± 12.5, P <.01). Total, free testosterone and free androgen index were higher in men (11.5, 36.6 and 40.6 fold, respectively, P <.01). AMPKα phosphorylation was 2.2-fold higher in men compared to women (P <.01). Total Ser221ACCβ and Thr286CaMKII fractional phosphorylation tended to be higher in men (P =.1). PGC1-α and SIRT1 total protein expression was similar in men and women, whereas CnA tended to be higher in men (P =.1). Basal AMPKα phosphorylation was linearly related to the percentage of MHC I in men (r = 0.56; P <.01), but not in women. No association was observed between anaerobic performance and basal phosphorylations in men and women, analysed separately. Conclusion: In summary, skeletal muscle basal AMPKα phosphorylation is higher in men compared to women, with no apparent effect on anaerobic performance. | en_US |
dc.language | eng | en_US |
dc.publisher | 1746-1391 | - |
dc.relation.ispartof | European Journal of Sport Science | en_US |
dc.source | European Journal of Sport Science [ISSN 1746-1391], v. 16 (4), p. 455-464 | en_US |
dc.subject | 241106 Fisiología del ejercicio | en_US |
dc.subject | 2411 Fisiología humana | en_US |
dc.subject.other | AMPK | - |
dc.subject.other | Anaerobic performance | - |
dc.subject.other | Gender | - |
dc.subject.other | Muscle phenotype | - |
dc.subject.other | Muscle signalling | - |
dc.title | Greater basal skeletal muscle AMPKα phosphorylation in men than in women: Associations with anaerobic performance | en_US |
dc.type | info:eu-repo/semantics/Article | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1080/17461391.2015.1063701 | en_US |
dc.identifier.isi | 000379773800009 | - |
dcterms.isPartOf | European Journal Of Sport Science | - |
dcterms.source | European Journal Of Sport Science[ISSN 1746-1391],v. 16 (4), p. 455-464 | - |
dc.description.lastpage | 464 | en_US |
dc.identifier.issue | 4 | - |
dc.description.firstpage | 455 | en_US |
dc.relation.volume | 16 | en_US |
dc.investigacion | Ciencias de la Salud | - |
dc.type2 | Artículo | en_US |
dc.identifier.wos | WOS:000379773800009 | - |
dc.contributor.daisngid | 861361 | - |
dc.contributor.daisngid | 2486534 | - |
dc.contributor.daisngid | 4392482 | - |
dc.contributor.daisngid | 1232764 | - |
dc.contributor.daisngid | 1264657 | - |
dc.contributor.daisngid | 7526316 | - |
dc.contributor.daisngid | 2738067 | - |
dc.contributor.daisngid | 1230811 | - |
dc.contributor.daisngid | 31470516 | - |
dc.contributor.daisngid | 9556190 | - |
dc.identifier.investigatorRID | H-9500-2015 | - |
dc.identifier.investigatorRID | D-2683-2009 | - |
dc.identifier.investigatorRID | H-4961-2016 | - |
dc.identifier.investigatorRID | H-8647-2016 | - |
dc.contributor.wosstandard | WOS:Guadalupe-Grau, A | - |
dc.contributor.wosstandard | WOS:Rodriguez-Garcia, L | - |
dc.contributor.wosstandard | WOS:Torres-Peralta, R | - |
dc.contributor.wosstandard | WOS:Morales-Alamo, D | - |
dc.contributor.wosstandard | WOS:Ponce-Gonzalez, JG | - |
dc.contributor.wosstandard | WOS:Perez-Suarez, I | - |
dc.contributor.wosstandard | WOS:Santana, A | - |
dc.contributor.wosstandard | WOS:Al Calbet, J | - |
dc.date.coverdate | 2016 | en_US |
dc.identifier.ulpgc | Sí | es |
dc.description.sjr | 1,128 | |
dc.description.jcr | 2,69 | |
dc.description.sjrq | Q1 | |
dc.description.jcrq | Q1 | |
dc.description.scie | SCIE | |
item.fulltext | Sin texto completo | - |
item.grantfulltext | none | - |
crisitem.author.dept | GIR IUIBS: Rendimiento humano, ejercicio físico y salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | GIR IUIBS: Rendimiento humano, ejercicio físico y salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | GIR IUIBS: Rendimiento humano, ejercicio físico y salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | GIR IUIBS: Rendimiento humano, ejercicio físico y salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Educación Física | - |
crisitem.author.dept | GIR IUIBS: Rendimiento humano, ejercicio físico y salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Ciencias Clínicas | - |
crisitem.author.dept | GIR IUIBS: Rendimiento humano, ejercicio físico y salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Educación Física | - |
crisitem.author.orcid | 0000-0002-0848-4260 | - |
crisitem.author.orcid | 0000-0002-0848-4260 | - |
crisitem.author.orcid | 0000-0001-8463-397X | - |
crisitem.author.orcid | 000-0002-1075-9948 | - |
crisitem.author.orcid | 0000-0002-9215-6234 | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.fullName | Sanchez De Torres Peralta,Rafael | - |
crisitem.author.fullName | Guadalupe Grau,Amelia | - |
crisitem.author.fullName | Sanchez De Torres Peralta,Rafael | - |
crisitem.author.fullName | Morales Álamo, David | - |
crisitem.author.fullName | Santana Rodríguez, Alfredo | - |
crisitem.author.fullName | López Calbet, José Antonio | - |
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