Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/52951
DC FieldValueLanguage
dc.contributor.authorVega Díaz, Nicanor Jesúsen_US
dc.contributor.authorGonzalez-Cabrera, Faynaen_US
dc.contributor.authorMarrero Robayna, Silvia Maríaen_US
dc.contributor.authorSantana Estupiñán, Raquelen_US
dc.contributor.authorGallego-Samper, Robertoen_US
dc.contributor.authorHenriquez Palop, Fernandoen_US
dc.contributor.authorPérez Borges, Patriciaen_US
dc.contributor.authorRodríguez-Pérez, José Carlosen_US
dc.contributor.otherRodriguez-Perez, J.C.-
dc.date.accessioned2019-02-04T14:28:21Z-
dc.date.available2019-02-04T14:28:21Z-
dc.date.issued2015en_US
dc.identifier.issn2077-0383en_US
dc.identifier.urihttp://hdl.handle.net/10553/52951-
dc.description.abstractBackground: In order to reduce the cardiovascular risk, morbidity and mortality of peritoneal dialysis (PD), a minimal level of small-solute clearances as well as a sodium and water balance are needed. The peritoneal dialysis solutions used in combination have reduced the complications and allow for a long-time function of the peritoneal membrane, and the preservation of residual renal function (RRF) in patients on peritoneal dialysis (PD) is crucial for the maintenance of life quality and long-term survival. This retrospective cohort study reviews our experience in automatic peritoneal dialysis (APD) patients, with end-stage renal disease (ESRD) secondary to diabetic nephropathy (DN) in comparison to non-diabetic nephropathy (NDN), using different PD solutions in combination. Design: Fifty-two patients, 29 diabetic and 23 non-diabetic, were included. The follow-up period was 24 months, thus serving as their own control. Results: The fraction of renal urea clearance (Kt) relative to distribution volume (V) (or total body water) (Kt/V), or creatinine clearance relative to the total Kt/V or creatinine clearance (CrCl) decreases according to loss of RRF. The loss of the slope of RRF is more pronounced in DN than in NDN patients, especially at baseline time interval to 12 months (loss of 0.29 mL/month vs. 0.13 mL/month, respectively), and is attenuated in the range from 12 to 24 months (loss of 0.13 mL/month vs. 0.09 mL/month, respectively). Diabetic patients also experienced a greater decrease in urine output compared to non-diabetic, starting from a higher baseline urine output. The net water balance was adequate in both groups during the follow up period. Regarding the balance sodium, no inter-group differences in sodium excretion over follow up period was observed. In addition, the removal of sodium in the urine output decreases with loss of renal function. The average concentration of glucose increase in the cycler in both groups (DN: baseline 1.44 +/- 0.22, 12 months 1.63 +/- 0.39, 24 months 1.73 +/- 0.47; NDN: baseline 1.59 +/- 0.40, 12 months 1.76 +/- 0.47, 24 months 1.80 +/- 0.46), in order to maintain the net water balance. The daytime dwell contribution, the fraction of day and the renal fraction of studies parameters provide sustained benefit in the follow-up time, above 30%. Conclusions: The wet day and residual renal function are determinants in the achievement of the objective dose of dialysis, as well as in the water and sodium balance. The cause of chronic kidney disease (CKD) does not seem to influence the cleansing effectiveness of the technique.en_US
dc.languageengen_US
dc.relation.ispartofJournal of Clinical Medicineen_US
dc.sourceJournal Of Clinical Medicine [ISSN 2077-0383], v. 4 (7), p. 1518-1535, (Julio 2015)en_US
dc.subject32 Ciencias médicasen_US
dc.subject3201 Ciencias clínicasen_US
dc.subject320506 Nefrologíaen_US
dc.subject.otherDiabetesen_US
dc.subject.otherAutomatic peritoneal dialysisen_US
dc.subject.otherAdequacyen_US
dc.subject.otherWater balanceen_US
dc.subject.otherSodium balanceen_US
dc.titleRenal Replacement Therapy: Purifying Efficiency of Automated Peritoneal Dialysis in Diabetic versus Non-Diabetic Patientsen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.3390/jcm4071518en_US
dc.identifier.isi000363144400010-
dcterms.isPartOfJournal Of Clinical Medicine-
dcterms.sourceJournal Of Clinical Medicine[ISSN 2077-0383],v. 4 (7), p. 1518-1535-
dc.description.lastpage1535en_US
dc.identifier.issue7-
dc.description.firstpage1518en_US
dc.relation.volume4en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.wosWOS:000363144400010-
dc.contributor.daisngid5807597-
dc.contributor.daisngid5539868-
dc.contributor.daisngid7027809-
dc.contributor.daisngid11934294-
dc.contributor.daisngid8151426-
dc.contributor.daisngid3952355-
dc.contributor.daisngid5812194-
dc.contributor.daisngid245684-
dc.description.notasThis article belongs to the Special Issue Diabetic Nephropathyen_US
dc.identifier.investigatorRIDC-1247-2010-
dc.description.numberofpages18en_US
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Vega-Diaz, N-
dc.contributor.wosstandardWOS:Gonzalez-Cabrera, F-
dc.contributor.wosstandardWOS:Marrero-Robayna, S-
dc.contributor.wosstandardWOS:Santana-Estupinan, R-
dc.contributor.wosstandardWOS:Gallego-Samper, R-
dc.contributor.wosstandardWOS:Henriquez-Palop, F-
dc.contributor.wosstandardWOS:Perez-Borges, P-
dc.contributor.wosstandardWOS:Rodriguez-Perez, JC-
dc.date.coverdateJulio 2015en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.scieSCIE-
item.grantfulltextopen-
item.fulltextCon texto completo-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.deptGIR IUIBS: Patología y Tecnología médica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.orcid0000-0003-0023-1063-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameVega Díaz, Nicanor Jesús-
crisitem.author.fullNameMarrero Robayna, Silvia María-
crisitem.author.fullNameSantana Estupiñán, Raquel-
crisitem.author.fullNameRodríguez Pérez,José Carlos-
Appears in Collections:Artículos
Adobe PDF (198,69 kB)
Show simple item record

WEB OF SCIENCETM
Citations

5
checked on Sep 29, 2024

Page view(s)

55
checked on Feb 3, 2024

Download(s)

9
checked on Feb 3, 2024

Google ScholarTM

Check

Altmetric


Share



Export metadata



Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.