Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/52607
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dc.contributor.authorNegrín-Báez, Daviniaen_US
dc.contributor.authorNavarro, Anaen_US
dc.contributor.authorRodríguez-Ramilo, Silvia T.en_US
dc.contributor.authorAfonso, Juan M.en_US
dc.contributor.authorZamorano, María J.en_US
dc.contributor.otherZamorano, Maria Jesus
dc.date.accessioned2018-12-04T17:22:12Z-
dc.date.available2018-12-04T17:22:12Z-
dc.date.issued2016en_US
dc.identifier.issn1436-2228en_US
dc.identifier.urihttp://hdl.handle.net/10553/52607-
dc.description.abstractMorphological abnormalities, especially skeletal deformities, are some of the most important problems affecting gilthead seabream (Sparus aurata L.) aquaculture industry. In this study, a QTL analysis for LSK complex deformity in gilthead seabream is reported. LSK complex is a severe deformity consisting of a consecutive repetition of three vertebral deformities: lordosis, scoliosis, and kyphosis. Seventy-eight offspring from six breeders from a mass-spawning were analyzed: five full-sibling families, three maternal, and two paternal half-sibling families. They had shown a significant association with the LSK complex prevalence in a previous segregation analysis. Fish were genotyped using a set of multiplex PCRs (ReMsa1-13), which includes 106 microsatellite markers. Two methods were used to perform the QTL analysis: a linear regression with the GridQTL software and a linear mixed model with the Qxpak software. A total of 18 QTL were identified. Four of them (QTLSK3, 6, 12, and 14), located in LG5, 8, 17, and 20, respectively, were the most solid ones. These QTL were significant at genome level and showed an extremely large effect (>35 %) with both methods. Markers close to the identified QTL showed a strong association with phenotype. Two of these molecular markers (DId-03-T and Bt-14-F) were considered as potential linked-to-this-deformity markers. The detection of these QTL supposes a critical step in the implementation of marker-assisted selection in this species, which could decrease the incidence of this deformity and other related deformities. The identification of these QTL also represents a major step towards the study of the etiology of skeletal deformities in this species.en_US
dc.languageengen_US
dc.relation.ispartofMarine Biotechnologyen_US
dc.sourceMarine Biotechnology[ISSN 1436-2228],v. 18, p. 98-106en_US
dc.subject251092 Acuicultura marinaen_US
dc.subject310907 Patologíaen_US
dc.subject310902 Genéticaen_US
dc.subject.otherGenetic improvementen_US
dc.subject.otherKyphosisen_US
dc.subject.otherLordosisen_US
dc.subject.otherMASen_US
dc.subject.otherQTLen_US
dc.subject.otherScoliosisen_US
dc.titleIdentification of Quantitative Trait Loci Associated with the Skeletal Deformity LSK complex in Gilthead Seabream (Sparus aurata L.)en_US
dc.typeinfo:eu-repo/semantics/Articlees
dc.typeArticlees
dc.identifier.doi10.1007/s10126-015-9671-7
dc.identifier.scopus84953363011
dc.identifier.isi000378136600008
dcterms.isPartOfMarine Biotechnology
dcterms.sourceMarine Biotechnology[ISSN 1436-2228],v. 18 (1), p. 98-106
dc.contributor.authorscopusid55644309600
dc.contributor.authorscopusid57212839113
dc.contributor.authorscopusid13612121000
dc.contributor.authorscopusid6507927559
dc.contributor.authorscopusid57201126472
dc.contributor.authorscopusid6701451831
dc.description.lastpage106-
dc.identifier.issue1-
dc.description.firstpage98-
dc.relation.volume18-
dc.investigacionCienciasen_US
dc.type2Artículoen_US
dc.identifier.wosWOS:000378136600008
dc.contributor.daisngid4127459
dc.contributor.daisngid2095438
dc.contributor.daisngid1606444
dc.contributor.daisngid1136306
dc.contributor.daisngid1009633
dc.identifier.investigatorRIDM-5052-2018
dc.contributor.wosstandardWOS:Negrin-Baez, D
dc.contributor.wosstandardWOS:Navarro, A
dc.contributor.wosstandardWOS:Rodriguez-Ramilo, ST
dc.contributor.wosstandardWOS:Afonso, JM
dc.contributor.wosstandardWOS:Zamorano, MJ
dc.date.coverdateFebrero 2016
dc.identifier.ulpgces
dc.description.sjr0,993
dc.description.jcr2,748
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR Grupo de Investigación en Acuicultura-
crisitem.author.deptIU de Investigación en Acuicultura Sostenible y Ec-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.deptGIR Grupo de Investigación en Acuicultura-
crisitem.author.deptIU de Investigación en Acuicultura Sostenible y Ec-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.orcid0000-0003-1569-9152-
crisitem.author.parentorgIU de Investigación en Acuicultura Sostenible y Ec-
crisitem.author.parentorgIU de Investigación en Acuicultura Sostenible y Ec-
crisitem.author.fullNameAfonso López, Juan Manuel-
crisitem.author.fullNameZamorano Serrano, María Jesús-
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