Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/52510
DC Field | Value | Language |
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dc.contributor.author | Hernández Vega, Julia Natividad | en_US |
dc.contributor.author | Rodríguez Hernández, Ángel | en_US |
dc.contributor.author | Stear, M. J. | en_US |
dc.contributor.author | Conde-Felipe, M. | en_US |
dc.contributor.author | Rodríguez, E. | en_US |
dc.contributor.author | Piedrafita, D. | en_US |
dc.contributor.author | González, J. F. | en_US |
dc.date.accessioned | 2018-11-28T10:51:42Z | - |
dc.date.available | 2018-11-28T10:51:42Z | - |
dc.date.issued | 2016 | en_US |
dc.identifier.issn | 0304-4017 | en_US |
dc.identifier.uri | http://hdl.handle.net/10553/52510 | - |
dc.description.abstract | Haemonchus contortus (H. contortus) is a haematophagous parasite which causes important economic losses in small ruminants. On the island of Gran Canaria, two sheep breeds coexist which differ in their susceptibility to the infection with H. contortus; the resistant Canaria Hair Breed (CHB) sheep and the susceptible Canaria Sheep (CS) breed. The major target of resistance mechanisms in CHB sheep are directed to the adult parasite stage, reducing the worm burden, and decreased length and fecundity of surviving worms. Mucosal IgA (mIgA) has been shown to be an important regulator of immunity in Haemonchus and Teladorsagia infections; through correlations with larval stages where such mechanisms as antibody-dependent cell cytotoxicity and enzyme inhibition may mediate resistance. Here for the first time, we demonstrate a significant negative correlation between mIgA and adult worm length and fecundity only in the resistant CHB sheep. In contrast, and as reported in other sheep breeds, mIgA was only negatively correlated against the larval stage in the more susceptible CS breed. This study suggests mIgA may play a role in resistance to both larval and adult stages. | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | Veterinary Parasitology | en_US |
dc.source | Veterinary Parasitology[ISSN 0304-4017],v. 223, p. 153-158 | en_US |
dc.subject | 310907 Patología | en_US |
dc.subject | 240112 Parasitología animal | en_US |
dc.subject.other | Canaria hair breed | en_US |
dc.subject.other | Canaria sheep | en_US |
dc.subject.other | Haemonchus contortus | en_US |
dc.subject.other | Immunoglobulin-A | en_US |
dc.subject.other | Sheep-nematoda | en_US |
dc.subject.other | Worm-length | en_US |
dc.title | Potential role for mucosal IgA in modulating Haemonchus contortus adult worm infection in sheep | en_US |
dc.type | info:eu-repo/semantics/Article | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1016/j.vetpar.2016.04.022 | en_US |
dc.identifier.scopus | 84964492993 | - |
dc.identifier.isi | 000377317200027 | - |
dc.contributor.authorscopusid | 57188977277 | - |
dc.contributor.authorscopusid | 57207006439 | - |
dc.contributor.authorscopusid | 26643256100 | - |
dc.contributor.authorscopusid | 7006119516 | - |
dc.contributor.authorscopusid | 57188974191 | - |
dc.contributor.authorscopusid | 6506630827 | - |
dc.contributor.authorscopusid | 6602358369 | - |
dc.contributor.authorscopusid | 7404492965 | - |
dc.description.lastpage | 158 | en_US |
dc.description.firstpage | 153 | en_US |
dc.relation.volume | 223 | en_US |
dc.investigacion | Ciencias de la Salud | en_US |
dc.type2 | Artículo | en_US |
dc.contributor.daisngid | 5685596 | - |
dc.contributor.daisngid | 13912365 | - |
dc.contributor.daisngid | 171112 | - |
dc.contributor.daisngid | 33646546 | - |
dc.contributor.daisngid | 30819941 | - |
dc.contributor.daisngid | 595971 | - |
dc.contributor.daisngid | 1988579 | - |
dc.utils.revision | Sí | en_US |
dc.contributor.wosstandard | WOS:Hernandez, JN | - |
dc.contributor.wosstandard | WOS:Hernandez, A | - |
dc.contributor.wosstandard | WOS:Stear, MJ | - |
dc.contributor.wosstandard | WOS:Conde-Felip, M | - |
dc.contributor.wosstandard | WOS:Rodriguez, E | - |
dc.contributor.wosstandard | WOS:Piedrafita, D | - |
dc.contributor.wosstandard | WOS:Gonzalez, JF | - |
dc.date.coverdate | Junio 2016 | en_US |
dc.identifier.ulpgc | Sí | en_US |
dc.contributor.buulpgc | BU-VET | en_US |
dc.description.sjr | 1,173 | |
dc.description.jcr | 2,356 | |
dc.description.sjrq | Q1 | |
dc.description.jcrq | Q1 | |
dc.description.scie | SCIE | |
item.fulltext | Sin texto completo | - |
item.grantfulltext | none | - |
crisitem.author.dept | GIR IUSA-ONEHEALTH 4. Producción y Biotecnología Animal | - |
crisitem.author.dept | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.dept | GIR IUIBS: Medio Ambiente y Salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | GIR Parasitología, dermatologia y biopatologia veterinaria | - |
crisitem.author.dept | GIR IUSA-ONEHEALTH 4. Producción y Biotecnología Animal | - |
crisitem.author.dept | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.dept | Departamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos | - |
crisitem.author.dept | GIR IUSA-ONEHEALTH 4. Producción y Biotecnología Animal | - |
crisitem.author.dept | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.dept | Departamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos | - |
crisitem.author.orcid | 0000-0002-3843-2509 | - |
crisitem.author.orcid | 0000-0001-8282-2750 | - |
crisitem.author.orcid | 0000-0002-9174-9708 | - |
crisitem.author.orcid | 0000-0001-8692-990X | - |
crisitem.author.orcid | 0000-0001-7374-9256 | - |
crisitem.author.parentorg | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | Departamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos | - |
crisitem.author.parentorg | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.parentorg | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.fullName | Hernández Vega, Julia Natividad | - |
crisitem.author.fullName | Rodríguez Hernández,Ángel | - |
crisitem.author.fullName | Stear, Michael | - |
crisitem.author.fullName | Conde De Felipe,Magnolia María | - |
crisitem.author.fullName | Rodríguez Ponce, Eligia | - |
crisitem.author.fullName | Piedrafita ,David | - |
crisitem.author.fullName | González Pérez, Jorge Francisco | - |
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