Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/52300
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dc.contributor.authorGonzález-Reimers, E.en_US
dc.contributor.authorArnay-de-la-Rosa, M.en_US
dc.contributor.authorVelasco Vázquez, Francisco Javieren_US
dc.contributor.authorAlemán-Valls, R.en_US
dc.contributor.authorDurán-Castellón, M. C.en_US
dc.contributor.authorDe la Vega-Prieto, M. J.en_US
dc.contributor.authorGalindo-Martín, L.en_US
dc.contributor.authorSantolaria-Fernández, F.en_US
dc.date.accessioned2018-11-25T19:08:16Z-
dc.date.available2018-11-25T19:08:16Z-
dc.date.issued2002en_US
dc.identifier.issn0946-2104en_US
dc.identifier.urihttp://hdl.handle.net/10553/52300-
dc.description.abstractThis study was performed in order to analyze the relative and combined effects of ethanol and protein deficiency on bone strontium, and the relation of bone strontium with bone calcium and magnesium, serum osteocalcin and some of the hormones which govern divalent ions metabolism as PTH, corticosterone and testosterone. Methods: Forty adult male Sprague Dawley rats were divided into 4 groups of 10 animals each and fed (following a pair-feeding process) the Lieber-DeCarli liquid rat control diet (18% protein), an isocaloric, 36% ethanol-containing diet, an isocaloric, 2% protein-containing diet and an isocaloric diet containing 2% protein and 36% ethanol, respectively. Eight weeks later, after sacrifice with lethal doses of ketamine, blood was obtained by direct cardiac puncture and centrifuged, in order to determine, by radioimmunoassay, osteocalcin, PTH, testosterone and corticosterone. We also removed the first and second lumbar vertebrae to determine by atomic absorption flame absorptiometry bone content of calcium, magnesium and strontium. Results: Bone strontium was lower in the ethanol-fed animals and higher in the 2% protein-fed animals, only ethanol exerting an independent effect, a negative interaction existing between the 2 factors. Bone strontium was directly related with bone calcium (r = 0.44), and inversely with serum albumin (r = -0.36, p < 0.05). Ethanol and protein deficiency may alter bone strontium content in the Lieber-de Carli rat model.en_US
dc.languageengen_US
dc.publisher0946-2104
dc.relation.ispartofTrace Elements and Electrocytesen_US
dc.sourceTrace Elements and Electrolytes[ISSN 0946-2104],v. 19, p. 165-168en_US
dc.subject32 Ciencias médicasen_US
dc.subject.otherNo disponible.en_US
dc.titleEffects of ethanol and low-protein diet on bone strontium and its relation with divalent ions' metabolismen_US
dc.typeinfo:eu-repo/semantics/articlees
dc.typeArticlees
dc.identifier.scopus0036080847-
dc.contributor.authorscopusid7004694989-
dc.contributor.authorscopusid6602716669-
dc.contributor.authorscopusid8108100300-
dc.contributor.authorscopusid6504136040-
dc.contributor.authorscopusid6507489002-
dc.contributor.authorscopusid6506267411-
dc.contributor.authorscopusid6602769410-
dc.contributor.authorscopusid6701348569-
dc.description.lastpage168-
dc.description.firstpage165-
dc.relation.volume19-
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.ulpgces
dc.description.scieSCIE
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptGIR Colonización de territorios insulares y continentales entre sociedades precapitalistas-
crisitem.author.orcid0000-0003-0339-3500-
crisitem.author.parentorgDepartamento de Ciencias Históricas-
crisitem.author.fullNameVelazco Vázquez,Francisco Javier-
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